Results 101 to 110 of about 4,325,962 (256)

Influência do sistema adenosinérgico nas respostas comportamentais de ansiedade, tolerância e reforço positivo induzidas pelo etanol em camundongos [PDF]

open access: yes, 2006
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia.Um número crescente de evidências tem apontado para o neuromodulador adenosina como um importante mediador de várias
Batista, Luciano da Conceição
core  

Altered expression of adenosine A1 receptor in the paraventricular thalamus and its role in the regulation of sleep

open access: yes陆军军医大学学报
Objective‍ ‍To explore the expression profile of adenosine A1 receptor in the paraventricular thalamic nucleus (PVT) in wakefulness/sleep state and its role in regulating sleep.
ZHU Yifeng, WANG Na, HU Junya
doaj   +1 more source

Anti-platelet therapy: ADP receptor antagonists. [PDF]

open access: yes, 2011
The P2Y(12) receptor on platelets with which ADP interacts has an important role in promoting platelet function and thereby platelet involvement in both haemostasis and thrombosis.
Heptinstall, S   +3 more
core   +1 more source

A3 Adenosine Receptors Modulate Hypoxia-inducible Factor-1a Expression in Human A375 Melanoma Cells

open access: yesNeoplasia: An International Journal for Oncology Research, 2005
Hypoxia-inducible factor-1 (HIF-1) is a key regulator of genes crucial to many aspects of cancer biology. The purine nucleoside, adenosine, accumulates within many tissues under hypoxic conditions, including that of tumors. Because the levels of both HIF-
Stefania Merighi   +8 more
doaj   +1 more source

Clinical significance of adenosine receptor agonists

open access: yes, 2020
Adenosine is a ubiquitous extracellular signaling molecule with essential functions in human physiology. Adenosine receptors have a widespread expression and extensive effects across different organs.
Adigun, Muhammed Oladimeji
core  

ADENOSINE RECEPTORS IN RESPIRATORY DISORDERS AS CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND MALIGNANT PLEURAL MESOTHELIOMA [PDF]

open access: yes, 2012
Adenosine is a purine nucleoside that is commonly expressed in the body and involved in a wide range of physiological processes. The effects of adenosine are mediated through specific G-protein coupled cell surface receptors, named A1, A2A, A2B and A3 ...
Targa, Martina
core  

Purines as potential morphogens during embryonic development [PDF]

open access: yes, 2012
Components of purinergic signalling are expressed in the early embryo raising the possibility that ATP, ADP and adenosine may contribute to the mechanisms of embryonic development.
Dale, Nicholas   +3 more
core   +1 more source

Degranulation of rat omental mast cells by A1 receptor agonists in vitro

open access: yesMediators of Inflammation, 1996
The haemodynamic effects of adenosine are thought to result in part from a release of mast cell amines via A3 receptor stimulation. To investigate the nature of the receptors involved in adenosine-induced mast cell degranulation in the rat isolated ...
A. M. Northover, B. J. Northover
doaj   +1 more source

Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

open access: yesJournal of Experimental Medicine, 2007
The study of T regulatory cells (T reg cells) has been limited by the lack of specific surface markers and an inability to define mechanisms of suppression.
S. Deaglio   +12 more
semanticscholar   +1 more source

A1 adenosine receptor evoked Ca2+ signals in astrocytes

open access: yesCurrent Directions in Biomedical Engineering
In addition to neurons, glial cells make up the nervous system. These glial cells are divided into macroglial cells - including astrocytes - and microglial cells.
Kienleitner Filip, Lenk Kerstin
doaj   +1 more source

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