Results 171 to 180 of about 2,608,509 (268)

Impact of the adenosine receptor A2BR expressed on myeloid cells on immune regulation during pregnancy. [PDF]

Eur J Immunol
Dietz S, Hebel J, Rühle J, Huff A, Eltzschig HK, Lajqi T, Poets CF, Gille C, Köstlin-Gille N.   +8 more
europepmc   +1 more source

Lactate Metabolic Reprogramming Mediated by CircRNA–LDHA Complex Facilitates Innate Immune Evasion of Liver Cancer

Advanced Science, EarlyView.
CircSMPD4 physically combines with lactate dehydrogenase A (LDHA) and reduces its acetylation level via SIRT2‐dependent deacetylation, thereby inhibiting chaperone‐mediated autophagy‐lysosome degradation of LDHA. Upregulating LDHA leads to increasing lactate production and extracellular export, which in turn suppresses natural killer cell cytotoxicity ...
Hao Shen, Boqiang Liu, Jing He, Weijun Zhao, Weiqi Li, Lingfeng Ma, Lidan Hou, Yi Wang, Chenqi Jin, Yushun Chang, Jie Lin, Jia Zhao, Binghan Jin, Yuanshi Tian, Xiujun Cai, Liang Shi, Yifan Wang   +16 more
wiley   +1 more source

Novel Quinazoline Derivatives as Highly Effective A2A Adenosine Receptor Antagonists. [PDF]

Molecules
Laversin A, Dufossez R, Bolteau R, Duroux R, Ravez S, Hernandez-Tapia S, Fossart M, Coevoet M, Liberelle M, Yous S, Lebègue N, Melnyk P.   +11 more
europepmc   +1 more source

Thermosensory TRPV Heterotetramers Drive Seasonal Polyphenism: Molecular Basis of CcIav/CcNan‐PKCα‐AKH/AKHR Signaling in Pear Psyllid Morph Transition

Advanced Science, EarlyView.
At 2 5 °C, thermal activation initiates: i) CcIav/CcNan heterotetramer assembly → Ca2⁺ influx; ii) CcPKCα phosphorylation → AKH signaling potentiation; iii) CcAKH1 binding to membrane‐localized CcAKHR → energy mobilization (lipid catabolism/glycogenolysis) and vitellogenin transport via follicular patency; iv) Oocyte maturation → summer‐form nymph ...
Jianying Li, Zhixian Zhang, Yilin Wang, Yue Yang, Jiarui Wang, Xueyi Ruan, Songdou Zhang   +6 more
wiley   +1 more source

Cryo-EM structures of adenosine receptor A₃AR bound to selective agonists. [PDF]

Nat Commun
Cai H, Guo S, Xu Y, Sun J, Li J, Xia Z, Jiang Y, Xie X, Xu HE.   +8 more
europepmc   +1 more source

2-Thioether 5‘-O-(1-Thiotriphosphate)adenosine Derivatives as New Insulin Secretagogues Acting through P2Y-Receptors

, 1999
Bilha Fischer, Ana Chulkin, José L. Boyer, Kendall T. Harden, Fernand‐Pierre Gendron, Adrien R. Beaudoin, J Chapal, Dominique Hillaire‐Buys, Pierre Petit   +8 more
openalex   +1 more source

Cordycepin induces apoptosis in human bladder cancer cells via activation of A3 adenosine receptors [PDF]

, 2017
Hong-Li Cao, Zijin Liu, Chang Zheng
openalex   +1 more source

TNEA Regulates Hippocampal Oscillation by Improving Inhibitory Synaptic Plasticity to Ameliorates Cognitive Impairment in Alzheimer's Disease

Advanced Science, EarlyView.
TNEA improves cognition in 5xFAD mice by modulating parvalbumin‐positive interneurons in hippocampal CA1. TNEA enhances gamma oscillations during rest and theta power during novel object recognition, restoring excitation/inhibition balance. These findings support TNEA as a minimally invasive therapy for Alzheimer's disease.
Zhongzhao Guo, Hong Ni, Yu Lu, Zhengyu Cui, Yixing Wang, Zilu Zhu, Xinyu Wei, Chenyi Xia, Ming Xu, Lixia Du, Yufang Yang, Shi Shu, Ke Wang, Zhifei Wang, Chunlei Shan, Deheng Wang   +15 more
wiley   +1 more source

Adenosine Receptor 3 in Liver Cancer: Expression Variability, Epigenetic Modulation, and Enhanced Histone Deacetylase Inhibitor Effects. [PDF]

Gastro Hep Adv
Kaldjob-Heinrich L, Nuciforo S, Lemke S, Stahl A, Czemmel S, Babaei S, Blukacz L, Meier MA, Zhang Y, Schürch CM, Gonzalez-Menendez I, Woelffing P, Malek NP, Scheble V, Nahnsen S, Claassen M, Templin M, Bösmüller H, Heim MH, Dauch D, Bitzer M.   +20 more
europepmc   +1 more source

Selective regulation of nuclear orphan receptors 4A by adenosine receptor subtypes in human mast cells [PDF]

, 2010
Li Zhang, Catherine Paine, Ramiro Dip
openalex   +1 more source