Results 191 to 200 of about 4,325,962 (256)

Translational Experimental Basis of Indirect Adenosine Receptor Agonist Stimulation for Bone Regeneration: A Review. [PDF]

open access: yesInt J Mol Sci
Ehlen QT   +7 more
europepmc   +1 more source

2-Aryladenine Derivatives as a Potent Scaffold for Adenosine Receptor Antagonists: The 6-Morpholino Derivatives. [PDF]

open access: yesMolecules
Areias F   +10 more
europepmc   +1 more source

Adenosine and adenosine receptors in colorectal cancer

International Immunopharmacology, 2020
CD39 (nucleoside triphosphate diphosphohydrolase) and Ecto-5-nucleotidase (CD73) have been recognized as important factors mediating various pathological and physiological responses in the tumor microenvironment. Elevated expression of CD73 and CD39 is correlated with the over-production of adenosine in the tumor region.
Farnaz, Hajizadeh   +7 more
openaire   +2 more sources

Adenosine and Adenosine Receptors

American Journal of Respiratory Cell and Molecular Biology, 1990
In the last decade, there has been renewed interest in extracellular signaling by adenosine and adenine nucleotides. The potent cardiovascular effects of these agents were originally described by Drury and Szent-Gy6rgyi in 1929 (1). This report was followed by a flurry of interest in the use of adenosine as an antihypertensive agent, which subsided ...
openaire   +3 more sources

Adenosine receptor subtypes

Trends in Pharmacological Sciences, 1993
The numerous and widespread effects of adenosine provide both an opportunity for the development of novel therapeutic agents acting via adenosine receptors and the challenge of achieving selectivity of action. The feasibility of achieving selectivity is enhanced if receptor subtypes can be identified.
M G, Collis, S M, Hourani
openaire   +2 more sources

Adenosine receptors and their modulators

Pharmaceutica Acta Helvetiae, 1993
The identification and characterization of adenosine receptors and the development of potent, receptor subtype-selective agonists and antagonists has been an active area of research for the past 20 years. Major recent advances in the field have been the cloning of several adenosine receptor subtypes of different species, including the discovery of a ...
C E, Müller, T, Scior
openaire   +2 more sources

Adenosine receptors and their ligands

Naunyn-Schmiedeberg's Archives of Pharmacology, 2000
The regulatory actions of adenosine are mediated via four subtypes of G protein-coupled receptors distinguished as A1, A2A, A2B and A3 receptors. Their presence on basically every cell makes them an interesting target for the pharmacological intervention in many pathophysiological situations.
openaire   +2 more sources

Adenosine receptors

2002
Abstract Adenosine is not a neurotransmitter but rather a paracrine neuromodulator. This obviously does not mean that adenosine is not biologically important—it just means that we must think differently about its role compared to, for example, dopamine or noradrenaline.
openaire   +2 more sources

Adenosine Receptors and Inflammation

2009
Extracellular adenosine is produced in a coordinated manner from cells following cellular challenge or tissue injury. Once produced, it serves as an autocrine- and paracrine-signaling molecule through its interactions with seven-membrane-spanning G-protein-coupled adenosine receptors.
Michael R, Blackburn   +3 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy