Results 201 to 210 of about 4,325,962 (256)

Adenosine and ATP Receptors in the Brain

Current Topics in Medicinal Chemistry, 2011
There is a widespread presence of both adenosine (P1) and P2 nucleotide receptors in the brain on both neurones and glial cells. Adenosine receptors play a major role in presynaptic neuromodulation, while P2X receptors are involved in fast synaptic transmission and synaptic plasticity. P2Y receptors largely mediate presynaptic activities.
Burnstock, Geoffrey, Fredholm, Bertil B., Verkhratsky, Alexei; id_orcid 0000-0003-2592-9898   +2 more
openaire   +3 more sources

Adenosine and ATP Receptors

2007
Adenosine and ATP, via P1 and P2 receptors respectively, can modulate pain transmission under physiological, inflammatory, and neuropathic pain conditions. Such influences reflect peripheral and central actions and effects on neurons as well as other cell types.
openaire   +2 more sources

International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors.

Pharmacological Reviews, 2001
Four adenosine receptors have been cloned and characterized from several mammalian species. The receptors are named adenosine A(1), A(2A), A(2B), and A(3).
B. Fredholm, A. IJzerman, K. Jacobson, K. Klotz, J. Linden   +4 more
semanticscholar   +1 more source

An adenosine receptor for olfaction

Science Signaling, 2017
Extracellular processing of ATP in the fish olfactory epithelium produces adenosine that is perceived by olfactory neurons.
openaire   +2 more sources

Adenosine Receptors in Health and Disease

2011
The adenosine receptors A(1), A(2A), A(2B), and A(3) are important and ubiquitous mediators of cellular signaling, which play vital roles in protecting tissues and organs from damage. In particular, adenosine triggers tissue protection and repair by different receptor-mediated mechanisms, including an increase of oxygen supply/demand ratio ...
GESSI, Stefania, MERIGHI, Stefania, VARANI, Katia, BOREA, Pier Andrea   +3 more
openaire   +3 more sources

Adenosine Receptors on Human Lymphocytes

1986
Evidence is accumulating that adenosine functions as an important immunoregulatory autacoid (1,2). Adenosine inhibits the mitotic response of human lymphocytes (3,4), lymphocyte-mediated cytolysis (5), superoxide anion generation by neutrophils (6), platelet aggregation (7) and mediator release from human basophils (8-10). The nucleoside has been shown
MARONE, GIANNI, R. PETRACCA, S. VIGORITA, M. PLAUT   +3 more
openaire   +4 more sources

Adenosine, adenosine receptors and glaucoma: An updated overview

Biochimica et Biophysica Acta (BBA) - General Subjects, 2013
Glaucoma, a leading cause of blindness worldwide, is an optic neuropathy commonly associated with elevated intraocular pressure (IOP). The major goals of glaucoma treatments are to lower IOP and protect retinal ganglion cells. It has been revealed recently that adenosine and adenosine receptors (ARs) have important roles in IOP modulation and ...
Yisheng, Zhong, Zijian, Yang, Wei-Chieh, Huang, Xunda, Luo   +3 more
openaire   +2 more sources

[Adenosine and adenosine receptors in the kidney].

Nihon rinsho. Japanese journal of clinical medicine, 1993
In the kidney, adenosine plays important regulatory roles, including renal blood flow, glomerular filtration rate, renin secretion, tubuloglomerular feedback, tubular reabsorption of sodium and water, sympathetic neurotransmitter release, and erythropoietin secretion.
S, Umemura, Y, Toya, K, Takeda, M, Kihara, T, Iwamoto, S, Yamaguchi, S, Kobayashi   +6 more
openaire   +1 more source

Adenosine receptors

Neuropharmacology, 1995
T M, Palmer, G L, Stiles
openaire   +2 more sources

Delineating the conformational landscape of the adenosine A2A receptor during G protein coupling

Cell, 2021
Duy Tran, Adnan Sljoka, Akio Kitao
exaly