Results 221 to 230 of about 2,801,899 (401)

Caffeine Mitigates Adenosine-Mediated Angiogenic Properties of Choroidal Endothelial Cells Through Antagonism of A₁ Adenosine Receptor and PI3K-AKT Axis. [PDF]

Cells
Park S, Song YS, Feng X, Sorenson CM, Sheibani N.   +4 more
europepmc   +1 more source

Adenosine receptor signalling in Alzheimer's disease. [PDF]

Purinergic Signal, 2022
Trinh PNH, Baltos JA, Hellyer SD, May LT, Gregory KJ.   +4 more
europepmc   +1 more source

Allosteric interactions between agonists and antagonists within the adenosine A2A receptor-dopamine D2 receptor heterotetramer

Proceedings of the National Academy of Sciences of the United States of America, 2015
J. Bonaventura, Gemma Navarro, Verònica Casadó-Anguera, Karima Azdad, W. Rea, E. Moreno, Marc Brugarolas, J. Mallol, E. Canela, C. Lluis, Antonio Cortés, N. Volkow, S. Schiffmann, S. Ferré, V. Casadó   +14 more
semanticscholar   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

Tumor-Associated Glycan Exploits Adenosine Receptor 2A Signaling to Facilitate Immune Evasion. [PDF]

Adv Sci (Weinh)
Cheng JY, Tsai HH, Hung JT, Hung TH, Lin CC, Lee CW, Lo ZC, Huang JR, Chiou SP, Huang Y, Chen SH, Yeh CN, Yu J, Yu AL.   +13 more
europepmc   +1 more source

Anxiolytic properties of A1 adenosine receptor PAMs

, 2016
Fabrizio Vincenzi, Pier Andrea Borea, Katia Varani   +2 more
openalex   +1 more source

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source

Structure-based discovery of positive allosteric modulators of the A₁ adenosine receptor. [PDF]

Proc Natl Acad Sci U S A
Nguyen ATN, Panel N, Vo DD, Thai BS, Chia LY, Lu CS, Hellyer SD, Langiu M, Jörg M, Gregory KJ, Kihlberg J, White PJ, Scammells PJ, Christopoulos A, Carlsson J, May LT.   +15 more
europepmc   +1 more source

Cardiac myocyte-secreted cAMP exerts paracrine action via adenosine receptor activation.

Journal of Clinical Investigation, 2014
Y. Sassi, A. Ahles, Dong-Jiunn Jeffery Truong, Younis Baqi, Sang-Yong Lee, B. Husse, J. Hulot, A. Foinquinos, T. Thum, C. Müller, A. Dendorfer, B. Laggerbauer, S. Engelhardt   +12 more
semanticscholar   +1 more source

Magnetically‐Induced Suppression of Oxidative Stress Prevents Venous Thrombosis

Advanced Science, EarlyView.
Venous thromboembolism (VTE) remains a leading cause of cardiovascular mortality. This study demonstrates that static magnetic fields (SMF) offer a novel non‐pharmacological intervention against VTE by mitigating endothelial oxidative stress. Mechanistically, SMF elevates intracellular Ca2+, boosts ATP production, and suppresses NOX4‐mediated ROS ...
Nana Zhang, Yirong An, Shiran Tao, Shenao Qu, Minge Wu, Guantong Fang, Ziqing Chen, Weilun Song, Haoze Leng, Rongqian Wu, Yi Lyu, Xiaoli Liu, Dinghui Dong   +12 more
wiley   +1 more source