Results 241 to 250 of about 350,006 (309)

2-Aryladenine Derivatives as a Potent Scaffold for Adenosine Receptor Antagonists: The 6-Morpholino Derivatives. [PDF]

Molecules
Areias F, Correia C, Rocha A, Teixeira S, Castro M, Brea J, Hu H, Carlsson J, Loza MI, Proença MF, Carvalho MA.   +10 more
europepmc   +1 more source

Failure of CGS15943A to block the hypotensive action of agonists acting at the adenosine A₃ receptor [PDF]

, 1994
M.V. Patel, Michael J. Sheehan, Peter Strong   +2 more
openalex   +1 more source

Inhibition of AMPKα Pathway by Podocyte GOLM1 Exacerbates Diabetic Nephrology in Mice

Advanced Science, EarlyView.
Podocyte Golgi membrane protein 1 interacts with epidermal growth factor receptor to inhibit peroxisome proliferator activated receptor γ, and then inactivates adenosine monophosphate activated protein kinase α pathway, which facilitates diabetes‐related inflammation, oxidative damage, apoptosis, and renal dysfunction.
Peng Xu, Kaiqiang Li, Huasong Liu, Aibo Xu, Zhewei Zhang, Yimin Yang, Xiaobo Lai, Ke Hao, Kui Fang, Zeyu Lai, Xiping Ou, Yuqun Cai, Zhen Wang, Keda Lu, Wanli Jiang   +14 more
wiley   +1 more source

Lipid Trolling to Optimize A₃ Adenosine Receptor-Positive Allosteric Modulators (PAMs). [PDF]

J Med Chem
Pradhan B, Pavan M, Fisher CL, Salmaso V, Wan TC, Keyes RF, Rollison N, Suresh RR, Kumar TS, Gao ZG, Smith BC, Auchampach JA, Jacobson KA.   +12 more
europepmc   +1 more source

Effects of Repeated Administration of KW-3902, a Novel Adenosine A1-Receptor Antagonist, on Its Pharmacological Actions

, 1993
Hideaki Kusaka, Akira Karasawa
openalex   +1 more source

Metabolic Programming Drives Protective and Inflammatory Monocyte Fates in Viral Encephalitis

Advanced Science, EarlyView.
Bone marrow monocytes infiltrate the West Nile virus‐infected brain and differentiate into HIF1‐α⁺ monocyte‐derived cells (MCs) that diverge into protective, antigen‐presenting or inflammatory, iNOS⁺ MCs with distinct metabolic programs and functions.
Claire L. Wishart, Alanna G. Spiteri, Jian Tan, Laurence Macia, Nicholas J. C. King   +4 more
wiley   +1 more source

A1 adenosine receptors of bovine brain couple to guanine nucleotide-binding proteins Gi1, Gi2, and Go.

, 1991
R Munshi, Iok-Hou Pang, Paul C. Sternweis, Joel Linden   +3 more
openalex   +1 more source

Engineering Neutrophil Vesicles for Synergistic Protection against Ischemia/Reperfusion Injury after Lung Transplant

Advanced Science, EarlyView.
Engineered neutrophil‐derived vesicles (SOD2‐Fer‐1@CVs) co‐delivering antioxidant and ferroptosis‐inhibitory agents enable inflammation‐targeted, ROS‐responsive therapy for ischemia–reperfusion injury in lung transplantation. Synergizing with ex vivo lung perfusion, this strategy alleviates oxidative stress and inflammation, restores vascular integrity,
Hao‐Xiang Yuan, Yu‐Yun Ye, Pu Shen, Jie Zhang, Qian‐Fang Meng, Ying Chen, Xin Xu, Xuan‐Lin Zhang, Lang Rao, Zhi‐Jin Fan, Jian‐Xing He   +10 more
wiley   +1 more source

Species difference in the G protein selectivity of the human and bovine A1-adenosine receptor.

, 1994
Ralf Jockers, Maurine E. Linder, M. Hohenegger, Christian Nanoff, Benjamin Bertin, A. Donny Strosberg, Stéfano Marullo, Michael Freissmuth   +7 more
openalex   +1 more source

Inductive‐Associative Meta‐learning Pipeline with Human Cognitive Patterns for Unseen Drug‐Target Interaction Prediction

Advanced Science, EarlyView.
Predicting unseen drug‐target interactions is challenging. BioBridge presents an Inductive‐Associative pipeline inspired by scientists' workflow. It combines transferable binding principles, learned via multi‐level encoders and adversarial training, with insights from weakly related references through meta‐learning.
Xiaoqing Lian, Tianxu Lv, Jie Zhu, Shiyun Nie, Hang Fan, Guosheng Wu, Yunjun Ge, Hong Xu, Xiaoting Wang, Lihua Li, Xiangxiang Zeng, Xiang Pan   +11 more
wiley   +1 more source