Results 81 to 90 of about 17,343 (255)

ATP Hysteresis in Tripartite Synapses [PDF]

open access: yesarXiv, 2009
Recent experimental studies strongly suggest the influence of glial purinergic transmission in the modulation of synaptic dynamics. By releasing adenosine triphosphate (ATP), which accumulates as adenosine, astrocytes tonically suppressed synaptic transmission. The delayed multi-step feedback of the glial adenosine with the neuron suggest the existence
arxiv  

Interpolated inverse discrete wavelet transforms in additive and non-additive spectral background correction [PDF]

open access: yesarXiv, 2023
We demonstrate the applicability of using interpolated inverse discrete wavelet transforms as a general tool for modeling additive or multiplicative background or error signals in spectra. Additionally, we propose an unsupervised way of estimating the optimal wavelet basis along with the model parameters.
arxiv  

Tissue levels of iron, copper, zinc and magnesium in iron deficient rats [PDF]

open access: yes, 2016
The effects of iron deficiency on the levels of iron, copper, zinc and magnesium in the brain, liver, kidney, heart and lungs of albino rats (Rattus novergicus) was investigated.
Oladiji, T.A.
core   +2 more sources

Decoding the role of large heat shock proteins in the progression of neuroinflammation‐mediated neurodegenerative disorders

open access: yesNeuroprotection, Volume 3, Issue 1, Page 48-62, March 2025.
This article summarizes the complex role of heat shock proteins (HSPs) in neurodegenerative disease progression. Several brain regions such as the hippocampus, cortex, basal ganglia, and brain stem are affected in diverse neurodegenerative diseases, including Alzheimer's, Parkinson's, Huntington's, and multiple sclerosis.
Shailendra K. Saxena   +6 more
wiley   +1 more source

Direct Growth Graphene on Cu Nanoparticles by Chemical Vapor Deposition as Surface-Enhanced Raman Scattering Substrate for Label-Free Detection of Adenosine [PDF]

open access: yesarXiv, 2015
We present a graphene/Cu nanoparticle hybrids (G/CuNPs) system as a surface-enhanced Raman scattering (SERS) substrate for adenosine detection. The Cu nanoparticles wrapped around a monolayer graphene shell were directly synthesized on flat quartz by chemical vapor deposition in a mixture of methane and hydrogen.
arxiv  

The Role of 8-Oxoguanine DNA Glycosylase-1 in Inflammation [PDF]

open access: yes, 2014
Many, if not all, environmental pollutants/chemicals and infectious agents increase intracellular levels of reactive oxygen species (ROS) at the site of exposure.
Andreoli   +27 more
core   +2 more sources

Alphavirus nsP2: A Multifunctional Regulator of Viral Replication and Promising Target for Anti‐Alphavirus Therapies

open access: yesReviews in Medical Virology, Volume 35, Issue 2, March 2025.
ABSTRACT Alphaviruses are re‐emerging vector‐born pathogens that cause arthralgia or encephalitic diseases on a global scale. While a vaccine against chikungunya virus was recently approved, no vaccines currently exist for other alphaviruses, nor are there antiviral drugs for the treatment of alphavirus infections. Alphaviruses have positive‐strand RNA
Sainan Wang   +2 more
wiley   +1 more source

Computational Study of Molecular Mechanisms of Caffeine Actions [PDF]

open access: yesarXiv, 2015
Caffeine (CAF) is one of the most widely and regularly consumed biologically active substances. We use computer simulation approach to the study of CAF activity by searching for its possible complexes with biopolymer fragments. The principal CAF target at physiologically important concentrations refers to adenosine receptors.
arxiv  

A comparison of an ATPase from the archaebacterium Halobacterium saccharovorum with the F1 moiety from the Escherichia coli ATP Synthase [PDF]

open access: yes
A purified ATPase associated with membranes from Halobacterium saccharovorum was compared with the F sub 1 moiety from the Escherichia coli ATP Synthase.
Hochstein, Lawrence I.   +1 more
core   +1 more source

DNLA Delayed the Appearance of Learning and Memory Impairment of APP/PS1 Mice: Involvement of mTOR/TFEB/v‐ATPase Signaling Pathway

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 3, March 2025.
The article unraveled that preventive administration of DNLA may delay the impairment of learning and memory in APP/PS1 mice. The molecular mechanism may be related to promoting the mTOR‐TFEB‐v‐ATPase pathway. ABSTRACT Introduction Alzheimer's disease (AD) is a progressive neurodegenerative disorder with cognitive impairment that currently is incurable.
Yajuan Wu   +6 more
wiley   +1 more source

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