Results 141 to 150 of about 2,006 (160)
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Biochimica Et Biophysica Acta - General Subjects, 1979
Abstract A fraction of adenosine bound to the cyclic AMP-adenosine binding protein/ S-adenosylhomocysteinase from mouse liver is almost instantaneously converted to adenine. The conversion ratio, defined ad the concentration of adenine divided by the sum of the concentrations of adenine and adenosine, and the sequestration of adenosine, determined as
Per Magne Ueland
exaly +3 more sources
Abstract A fraction of adenosine bound to the cyclic AMP-adenosine binding protein/ S-adenosylhomocysteinase from mouse liver is almost instantaneously converted to adenine. The conversion ratio, defined ad the concentration of adenine divided by the sum of the concentrations of adenine and adenosine, and the sequestration of adenosine, determined as
Per Magne Ueland
exaly +3 more sources
The Centrality of S-Adenosylhomocysteinase in the Regulation of the Biological Utilization of S-Adenosylmethionine [PDF]
, 1986 S-Adenosylhomocysteine (AdoHcy), first isolated as one of the products of transmethylation reactions from S-adenosylmethionine (AdoMet) (Cantoni & Scarano, 1954) has been shown to be a competitive inhibitor of all methyltransferases. This was first shown by Gibson et al.
Giulio L. Cantoni
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Kinetic Properties of Human Erythrocyte Adenosylhomocysteinase [PDF]
, 1986 SALERNO, Costantino +3 more
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Adenosylhomocysteinase from Yellow Lupin Seeds
European Journal of Biochemistry, 1977Adenosylhomocysteinase from yellow lupin seeds (Lupinus luteus) has been purified to homogeneity.Active enzyme, Mr= 110 000, consists of two probably identical subunits with Mr= 55 000 as judged by gel filtration and dodecyl sulphate/polyacrylamide gel electrophoresis in the presence of 2‐mercaptoethanol.
A, Guranowski, J, Pawelkiewicz
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Biology of Reproduction, 2023
Abstract Adenosylhomocysteinase (AHCY), a key enzyme in the methionine cycle, is essential for the development of embryos and the maintenance of mouse embryonic stem cells (mESCs). However, the precise underlying mechanism of Ahcy in regulating pluripotency remains unclear.
Qi, Jiang +8 more
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Abstract Adenosylhomocysteinase (AHCY), a key enzyme in the methionine cycle, is essential for the development of embryos and the maintenance of mouse embryonic stem cells (mESCs). However, the precise underlying mechanism of Ahcy in regulating pluripotency remains unclear.
Qi, Jiang +8 more
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Journal of Microbiology, 2020
Hepatitis C virus (HCV) life cycle is highly dependent on cellular proteins for viral propagation. In order to identify the cellular factors involved in HCV propagation, we previously performed a protein microarray assay using the HCV nonstructural 5A (NS5A) protein as a probe.
Yun-Sook, Lim +5 more
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Hepatitis C virus (HCV) life cycle is highly dependent on cellular proteins for viral propagation. In order to identify the cellular factors involved in HCV propagation, we previously performed a protein microarray assay using the HCV nonstructural 5A (NS5A) protein as a probe.
Yun-Sook, Lim +5 more
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Biochemistry, 1981
Plant (Lupinus luteus) S-adenosylhomocysteinase, an alpha 2 dimer, forms a 1:2 enzyme-adenosine complex. The binding sites for adenosine are not equivalent. Binding of the first molecule of adenosine is fast (k greater than 7 x 10(5) M-1 s-1), whereas the second molecule of adenosine binds in a slow process with a half-life of 5 min. Adenosine in the 1:
H, Jakubowski, A, Guranowski
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Plant (Lupinus luteus) S-adenosylhomocysteinase, an alpha 2 dimer, forms a 1:2 enzyme-adenosine complex. The binding sites for adenosine are not equivalent. Binding of the first molecule of adenosine is fast (k greater than 7 x 10(5) M-1 s-1), whereas the second molecule of adenosine binds in a slow process with a half-life of 5 min. Adenosine in the 1:
H, Jakubowski, A, Guranowski
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Nucleosides and Nucleotides, 1982
Abstract 9-β-D-Arabinofuranosyldeazaadenines [1-deaza-araA (4a) and 3-deaza-araA (4b)] were prepared from 6-chloro-β-D-ribofuranosyl-1- (6a) and -3-deazapurine (6b), respectively. Synthesis of 2′-deoxy-1-deaza-adenosine (5a) from 1-deazaadenosine (6c) is also described.
Tomokazu Sugawara +3 more
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Abstract 9-β-D-Arabinofuranosyldeazaadenines [1-deaza-araA (4a) and 3-deaza-araA (4b)] were prepared from 6-chloro-β-D-ribofuranosyl-1- (6a) and -3-deazapurine (6b), respectively. Synthesis of 2′-deoxy-1-deaza-adenosine (5a) from 1-deazaadenosine (6c) is also described.
Tomokazu Sugawara +3 more
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