Leaf apoplastic proteome composition in UV-B treated Arabidopsis thaliana mutants impaired in extracellular glutathione degradation [PDF]
In plants, environmental perturbations often result in oxidative reactions in the apoplastic space, which are counteracted for by enzymatic and non-enzymatic antioxidative systems, including ascorbate and glutathione. The occurrence of the latter and its
Arrigoni, Giorgio +2 more
core +1 more source
Folate Network Genetic Variation, Plasma Homocysteine, and Global Genomic Methylation Content: A Genetic Association Study [PDF]
Background: Sequence variants in genes functioning in folate-mediated one-carbon metabolism are hypothesized to lead to changes in levels of homocysteine and DNA methylation, which, in turn, are associated with risk of cardiovascular disease.
Baccarelli, Andrea +11 more
core +1 more source
A Strain Capable of Reducing Aflatoxin B1: Identification, Optimization of Removal Conditions and Transcriptomic Analysis of Degradation Pathways [PDF]
In this study, a strain of Wickerhamiella versatilis capable of degrading aflatoxin B1 (AFB1) was obtained. The removal conditions of AFB1 by this strain were optimized and important physiological and metabolic processes were elucidated using ...
WANG Lihui, PEI Yangyang, CHEN Xiaoru, ZHAO Huan, LIU Shuliang, HU Kaidi, ZHAO Ning, LI Qin, LI Jianlong
doaj +1 more source
LC-MS proteomics analysis of the iInsulin/IGF-1-deficient Caenorhabditis elegans daf-2(e1370) mutant reveals extensive restructuring of intermediary metabolism [PDF]
The insulin/IGF-1 receptor is a major known determinant of dauer formation, stress resistance, longevity, and metabolism in Caenorhabditis elegans. In the past, whole-genome transcript profiling was used extensively to study differential gene expression ...
Braeckman, Bart +7 more
core +2 more sources
The mechanism of action of S-adenosylhomocysteinase.
S-Adenosylhomocysteinase catalyzes the reversible hydrolysis of S-adenosyl-L-homocysteine (AdoHcy) to adenosine and L-homocysteine without added cofactors. A mechanism is proposed which involves oxidation of the 3'-hydroxyl group of AdoHcy by enzyme-bound NAD+.
J L, Palmer, R H, Abeles
openaire +2 more sources
Fermentative N-Methylanthranilate Production by Engineered Corynebacterium glutamicum
The N-functionalized amino acid N-methylanthranilate is an important precursor for bioactive compounds such as anticancer acridone alkaloids, the antinociceptive alkaloid O-isopropyl N-methylanthranilate, the flavor compound O-methyl-N-methylanthranilate,
Tatjana Walter +9 more
doaj +1 more source
Functions of S-nitrosylation in plant hormone networks [PDF]
In plants, a wide frame of physiological processes are regulated in liaison by both, nitric oxide (NO) and hormones. Such overlapping roles raise the question of how the cross-talk between NO and hormones trigger common physiological responses.
Casalongue, Claudia +3 more
core +2 more sources
Harvest index, a parameter conditioning responsiveness of wheat plants to elevated CO2 [PDF]
The expansion of the world’s population requires the development of high production agriculture. For this purpose, it is essential to identify target points conditioning crop responsiveness to predicted [CO2].
Aranjuelo, I. +6 more
core +1 more source
RN181 suppresses hepatocellular carcinoma growth by inhibition of the ERK/MAPK pathway. [PDF]
UNLABELLED: The activation of oncogenes and the inactivation of tumor suppressor genes by mutations or chronic hepatitis virus infections play key roles in the pathogenesis of hepatocellular carcinoma (HCC).
Brophy +36 more
core +1 more source
Chemical modification of arginine residues of rat liver S-adenosylhomocysteinase.
Rat liver S-adenosylhomocysteinase (EC 3.3.1.1) is inactivated by phenylglyoxal following pseudo-first order kinetics. The dependence of the apparent first order rate constant for inactivation on the phenylglyoxal concentration shows that the inactivation is second order in reagent. This fact together with the reversibility of inactivation upon removal
Y, Takata, M, Fujioka
openaire +2 more sources

