Data_Sheet_2_Prognostic Value of Serum Exosomal AHCY Expression in Hepatitis B-Induced Liver Cirrhosis.PDF [PDF]
, 2021 Objective: We aimed to investigate serum exosomal adenosylhomocysteinase (AHCY) expression in hepatitis B-induced liver cirrhosis (HBV-LC) patients and to determine the prognostic value of serum exosomal AHCY.Methods: We collected serum samples from 100 ...
Hongmei Wang (190581) +5 more
core +1 more source
CBS, PHGDH and PSAT1 interactive gene network. [PDF]
, 2016 The differentially expressed genes CBS, PHGDH and PSAT1 interactive network generated automatically using the STRING database (STRING software 9.1) is shown here.
Indira Hewlett (329203) +6 more
core +1 more source
Table_1_Prognostic Value of Serum Exosomal AHCY Expression in Hepatitis B-Induced Liver Cirrhosis.XLSX [PDF]
, 2021 Objective: We aimed to investigate serum exosomal adenosylhomocysteinase (AHCY) expression in hepatitis B-induced liver cirrhosis (HBV-LC) patients and to determine the prognostic value of serum exosomal AHCY.Methods: We collected serum samples from 100 ...
Hongmei Wang (190581) +5 more
core +1 more source
Association network analysis identifies enzymatic components of gut microbiota that significantly differ between colorectal cancer patients and healthy controls [PDF]
PeerJ, 2019 The human gut microbiota plays a major role in maintaining human health and was recently recognized as a promising target for disease prevention and treatment.
Dongmei Ai +4 more
doaj +2 more sources
The mechanism of action of S-adenosylhomocysteinase.
Journal of Biological Chemistry, 1979 S-Adenosylhomocysteinase catalyzes the reversible hydrolysis of S-adenosyl-L-homocysteine (AdoHcy) to adenosine and L-homocysteine without added cofactors. A mechanism is proposed which involves oxidation of the 3'-hydroxyl group of AdoHcy by enzyme-bound NAD+.
J L, Palmer, R H, Abeles
openaire +2 more sources
337 Targeting metabolic and epigenetic programs to re-sensitize glioblastoma to chemotherapy
Journal of Clinical and Translational Science, 2023 OBJECTIVES/GOALS: Treatment options for glioblastoma (GBM) are limited. Prognosis remains dismal, with an 18 month on average survival rate following diagnosis due to treatment resistance and disease recurrence. The goal of this project is to investigate
Emma Rowland +5 more
doaj +1 more source
Characterization of Timed Changes in Hepatic Copper Concentrations, Methionine Metabolism, Gene Expression, and Global DNA Methylation in the Jackson Toxic Milk Mouse Model of Wilson Disease [PDF]
, 2014 BACKGROUND: Wilson disease (WD) is characterized by hepatic copper accumulation with progressive liver damage to cirrhosis. This study aimed to characterize the toxic milk mouse from The Jackson Laboratory (Bar Harbor, ME, USA) (tx-j) mouse model of WD ...
Le, Anh +19 more
core +1 more source
Frontiers in Plant Science, 2021 Somatic embryogenesis is the process by which bipolar structures with no vascular connection with the surrounding tissue are formed from a single or a group of vegetative cells, and in conifers it can be divided into five different steps: initiation ...
Ander Castander-Olarieta +9 more
doaj +1 more source
Interactions of (−)-ilimaquinone with methylation enzymes: implications for vesicular-mediated secretion [PDF]
, 1999 BackgroundThe marine sponge metabolite (−)-ilimaquinone has antimicrobial, anti-HIV, anti-inflammatory and antimitotic activities, inhibits the cytotoxicity of ricin and diptheria toxin, and selectively fragments the Golgi apparatus.
Snapper, Marc L +3 more
core +1 more source
Discovery of AHCY as an Off-Target of Doxorubicin by Integrative Analysis of Photoaffinity Labeling Chemoproteomics and Untargeted Metabolomics [PDF]
, 2022 Target identification is critically important for understanding the mechanism of action of drugs. Here, we reported a new strategy for deconvolution of drug targets (or off-targets) with photoaffinity labeling chemoproteomics in combination with ...
Yanan Du (635727) +6 more
core +3 more sources