Results 1 to 10 of about 314,751 (339)
Cytokine Responses to Adenovirus and Adenovirus Vectors
Viruses, 2022 The expression of cytokines and chemokines in response to adenovirus infection is tightly regulated by the innate immune system. Cytokine-mediated toxicity and cytokine storm are known clinical phenomena observed following naturally disseminated ...
Svetlana Atasheva +1 more
doaj +3 more sources
Adenovirus Biology, Recombinant Adenovirus, and Adenovirus Usage in Gene Therapy [PDF]
Viruses, 2021 Gene therapy is currently in the public spotlight. Several gene therapy products, including oncolytic virus (OV), which predominantly replicates in and kills cancer cells, and COVID-19 vaccines have recently been commercialized. Recombinant adenoviruses,
Maki Watanabe +3 more
doaj +3 more sources
Pediatrics In Review, 2010 Of the 53 different human adenovirus (HAdV) serotypes belonging to species A-G, a significant number are associated with acute respiratory, gastrointestinal and ocular infections. Replication-defective HAdV-5-based vectors also continue to play a significant role in gene transfer trials and in vaccine delivery efforts in the clinic.
Jason G, Smith +3 more
openaire +4 more sources
, 1966 Adenovirus encodes for the pVII protein, which interacts and modulates virus DNA structure in the infected cells. The pVII protein is synthesized as the precursor protein and undergoes proteolytic processing by viral proteinase Avp, leading to release of
Inturi, Raviteja +2 more
core +11 more sources
Frontiers in Pediatrics, 2021 Objectives: To identify the differences of clinical characteristics and outcomes of severe pneumonia in children under 5 years old with and without adenovirus infection.Methods: A retrospective cohort study was conducted in three pediatric hospitals in ...
Lingling Zheng +8 more
doaj +1 more source
Pandemic influenza virus 2009 H1N1 and adenovirus in a high risk population of young adults: epidemiology, comparison of clinical presentations, and coinfection. [PDF]
PLoS ONE, 2014 BACKGROUND: In 2009, pandemic H1N1 influenza virus (2009 H1N1) emerged worldwide, causing morbidity and mortality that disproportionately affected young adults.
Heather C Yun +5 more
doaj +1 more source
A novel psittacine adenovirus identified during an outbreak of avian chlamydiosis and human psittacosis: zoonosis associated with virus-bacterium coinfection in birds. [PDF]
PLoS Neglected Tropical Diseases, 2014 Chlamydophila psittaci is found worldwide, but is particularly common among psittacine birds in tropical and subtropical regions. While investigating a human psittacosis outbreak that was associated with avian chlamydiosis in Hong Kong, we identified a ...
Kelvin K W To +14 more
doaj +1 more source
Adenovirus Core Proteins: Structure and Function
Viruses, 2021 Adenoviruses have served as a model for investigating viral-cell interactions and discovering different cellular processes, such as RNA splicing and DNA replication.
Shermila Kulanayake, Suresh K. Tikoo
doaj +1 more source
Altering the Ad5 packaging domain affects the maturation of the Ad particles. [PDF]
PLoS ONE, 2011 We have previously described a new family of mutant adenoviruses carrying different combinations of attB/attP sequences from bacteriophage PhiC31 flanking the Ad5 packaging domain.
Raul Alba +5 more
doaj +1 more source
Successful Treatment of Severe Adenoviral ARDS Using Cidofovir in a Case with Cerebral Palsy
Journal of Pediatric Emergency and Intensive Care Medicine, 2021 Adenovirus is a non-enveloped, double-stranded DNA virus that can cause infections in the upper and lower respiratory tract, conjunctiva, and gastrointestinal tract. Adenovirus infections are usually mild but may cause mortality and morbidity, especially
Emrah Gün +7 more
doaj +1 more source