Circumventing antivector immunity: potential use of nonhuman adenoviral vectors [PDF]
, 2014 Adenoviruses are efficient gene delivery vectors based on their ability to transduce a wide variety of cell types and drive high-level transient transgene expression. While there have been advances in modifying human adenoviral (HAdV) vectors to increase
Beard C.W. +30 more
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Sakarya Tıp Dergisi, 2019 ÖZET Amaç: Rotavirüs ve enterik adenovirüsler, çocukluk çağında gastroenteritlere bağlı hastaneye yatışların çoğunluğundan sorumludur. Rotavirüs ve enterik adenovirüs gastroenteritlerinin bölgemizdeki epidemiyolojisini araştırmak için hastanemize ...
Gürkan Muratdağı, Özlem Kirişci
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The Revolving Door of Adenovirus Cell Entry: Not All Pathways Are Equal
Pharmaceutics, 2021 Adenoviruses represent exceptional candidates for wide-ranging therapeutic applications, from vectors for gene therapy to oncolytics for cancer treatments.
Davor Nestić +5 more
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Assessment of a novel, capsid-modified adenovirus with an improved vascular gene transfer profile [PDF]
, 2013 <p>Background: Cardiovascular disorders, including coronary artery bypass graft failure and in-stent restenosis remain significant opportunities for the advancement of novel therapeutics that target neointimal hyperplasia, a characteristic of both ...
AA Soyombo +47 more
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Revista do Instituto de Medicina Tropical de São Paulo, 1992 The obtainment of monoclonal antibodies for adenovirus species 4(Ad4) is described.The specificities of selected monoclonal antibodies were determined by means of viral neutralization test in cell culture, immunofluorescence and Enzyme-Linked ...
Terezinha Maria de Paiva +6 more
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Frontiers in Medicine, 2022 BackgroundViral causes of acute respiratory distress syndrome (ARDS) are mostly limited to influenza. However, adenovirus has been emerging as a cause of ARDS with a high mortality rate and described in adults are rare.MethodsWe conducted a prospective ...
Zhan Wu +10 more
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High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles. [PDF]
, 1992 The Boltzmann transport equation is commonly considered to be the best semi-classical description of carrier transport in semiconductors, providing precise information about the distribution of carriers with respect to time (one dimension), location ...
Birnstiel, Max L. +5 more
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No more helper adenovirus: production of gutless adenovirus (GLAd) free of adenovirus and replication-competent adenovirus (RCA) contaminants [PDF]
Experimental & Molecular Medicine, 2019 AbstractGene therapy is emerging as an effective treatment option for various inherited genetic diseases. Gutless adenovirus (GLAd), also known as helper-dependent adenovirus (HDAd), has many notable characteristics as a gene delivery vector for this particular type of gene therapy, including broad tropism, high infectivity, a large transgene cargo ...
Hyun Jung Junn +5 more
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Improved induction of anti-melanoma T cells by adenovirus-5/3 fiber modification to target human DCs [PDF]
, 2018 To mount a strong anti-tumor immune response, non T cell inflamed (cold) tumors may require combination treatment encompassing vaccine strategies preceding checkpoint inhibition.
Chondronasiou, Dafni +9 more
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Carbohydrate receptor-mediated gene transfer to human T leukaemic cells [PDF]
, 1994 The mucin-type carbohydrate Tn cryptantigen (GalNAcα1-O-Ser/Thr, where GalNAc is N-acetyl-D-galactosamine) is expressed in many carcinomas, in haemopoietic disorders including the Tn syndrome, and on human immunodeficiency virus (HIV) coat glycoproteins,
Berger, Eric G. +8 more
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