Identification of Inhibitors and Drug Targets for Human Adenovirus Infections
Adenoviruses can cause infections in people of all ages at all seasons of the year. Adenovirus infections cause mild to severe illnesses. Children, immunocompromised patients, or those with existing respiratory or cardiac disease are at higher risk ...
Minli Liu +4 more
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Deaths Associated with Human Adenovirus-14p1 Infections, Europe, 2009–2010
Human adenovirus (HAdV) serotype 14 is rarely identified. However, an emerging variant, termed HAdV-14p1, recently has been described in the United States in association with outbreaks of acute respiratory disease with high rates of illness and death. We
Michael J. Carr +10 more
doaj +3 more sources
Antibody to human adenovirus early antigens during acute adenovirus infections [PDF]
The antibody (Ab) response to human adenovirus (AV) early antigens (EA) in acute AV infections was studied by the immunoperoxidase antibody technique for determining virus-specific immunoglobulin G (IPA-IgG). AV-EA-Ab appeared about 5 days after the onset of clinical symptoms, reached a peak 15 to 30 days later, and declined in titer after a few months.
G, Gerna +4 more
openaire +2 more sources
Current status of human adenovirus infection in China
Abstract Background Outbreaks of severe, acute hepatitis among children have recently attracted global attention. The pathogen causing the outbreak remains unknown, but there is growing evidence that it may be associated with human adenovirus (HAdV). Data sources A review of
Mao, Nai-Ying +3 more
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Association of Adenovirus Infection with Human Obesity [PDF]
AbstractDHURANDHAR, NIKHIL V, PUSHPA R KULKARNI, SHARAD M AJINKYA, ABHAYA A SHERIKAR, RICHARD L ATKINSON. Association of adenovirus infection with human obesity.We previously reported that chickens infected with the avian adenovirus SMAM‐1 developed a unique syndrome characterized by excessive intra‐abdominal fat deposition accompanied by paradoxically
N V, Dhurandhar +4 more
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Humanized Mice Reproduce Acute and Persistent Human Adenovirus Infection [PDF]
Severe human adenovirus (HAdV) infections are an increasing threat for immunosuppressed individuals, particularly those who have received stem cell transplants. It has been previously hypothesized that severe infections might be due to reactivation of a persistent infection, but this hypothesis has been difficult to test owing to the lack of a ...
Estefanía, Rodríguez +9 more
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Productive infection of cultured human lymphoid cells by adenovirus [PDF]
We investigated infection of cultures from established human B- and T-cell lines by adenoviruses. Infection by adenovirus type 2 or 5 was productive by the criteria of viral DNA replication, RNA synthesis, immunofluorescent staining of viral proteins, and assembly of biologically active virions.
D, Lavery +3 more
openaire +2 more sources
KIR3DS1 directs NK cell–mediated protection against human adenovirus infections
KIR3DS1 + NK cells execute enhanced killing of adenovirus-infected cells, providing protection against severe infection in immunocompromised hosts.
Johannes M. Jung +27 more
openaire +4 more sources
Incidence of viral respiratory infections in a prospective cohort of outpatient and hospitalized children aged ≤5 years and its associated cost in Buenos Aires, Argentina [PDF]
Background: Although information about the incidence of viral respiratory illnesses and their associated cost can help health officials explore the value of interventions, data are limited from middle-income countries.
Azziz Baumgartner, Eduardo +6 more
core +1 more source
Adenovirus replication and host innate response in primary human airway epithelial cells
Background: Adenovirus infections are very common in children and sometimes fatal. Immune responses and hypercytokinemia are related to disease severity in patients with adenovirus infection.
Tzu-I Yang +7 more
doaj +1 more source

