Stimulation of Human Adenovirus Infection Modulated by Emerging Micropollutants
Abstract Contaminants of emergent concern (CECs), such as pharmaceuticals and microplastics, are increasingly found in aquatic environments, yet their interactions with viral pathogens remain underexplored. This study evaluated the effects of antibiotics, antidepressants, microfibers, and nanoplastics on human adenovirus type 5 (HAdV ...
Catielen Paula Pavi +4 more
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Human adenovirus infections: update and consideration of mechanisms of viral persistence [PDF]
Purpose of review To provide an update on recent studies of human adenoviral (HAdV) infections and to explore the mechanisms of viral persistence and the role of persistent infection in disseminated disease in immunocompromised patients.
Jay R, Radke, James L, Cook
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Adenovirus infection reverses the antiviral state induced by human interferon [PDF]
HeLa cells treated with human lymphoblastoid interferon do not synthesize poliovirus proteins. The antiviral state against poliovirus is reversed if cells are previously infected with adenovirus type 5. A late gene product seems to be involved in this reversion, since no effect is observed at early stages of infection or in the presence of aphidicolin.
Feduchi, Elena, Carrasco, Luis
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Hemagglutination-Inhibition Antibody Responses in Human Adenovirus Infections
SummaryPaired sera from 36 children naturally infected with adenovirus types 1, 2, 3, or 5 and from 27 adults naturally infected with adenovirus types 4 or 7 were studied for homotypic and heterotypic hem-agglutination-inhibition (HI) antibodies and for complement-fixing (CF) antibody. Homotypic HI responses were observed in most instances. Heterotypic
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Data on the expression of cellular lncRNAs in human adenovirus infected cells
Expression of cellular long non-coding RNAs (lncRNAs) in human primary lung fibroblasts (IMR-90) during the course of adenovirus type 2 (Ad2) infection was studied by strand-specific whole transcriptome sequencing. In total, 645 cellular lncRNAs were expressed at a significant level and 398 of them were changed more than 2-fold.
Chen M, Zhao H, Lind SB, Pettersson U
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Attempts to Infect Rhesus Monkeys with Human Type 4 Adenovirus
SummaryIn searching for an animal model for human adenovirus studies we have attempted to infect rhesus monkeys with a human type 4 adenovirus. The results were inconclusive but we have some evidence to suggest that infection and replication might have occurred in several animals. Communicability among cagemates was not demonstrated.
F A, Pedreira +4 more
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Molecular epidemiology of human adenovirus infections in Denmark, 2011–2016
Human adenoviruses (HAdVs) can cause respiratory tract infections, conjunctivitis, diarrhoea and outbreaks have been reported. However, little is known about the disease burden and the molecular epidemiology of HAdV.To retrospectively perform a molecular characterization of HAdV positive samples received at Statens Serum Institut during the period 2011-
Barnadas, Céline +3 more
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Persistent Infection of Human Cells (HeLa) with Adenovirus Type 12.
SummaryThe establishment of an adeno-virus type 12 cell carrier system is described. Characteristics of the carrier cultures include an initial dependence on inhibitor or antibody in human serum, an enhanced rate of growth after the fifth day as compared to uninfected cells, a relatively high percentage of infected cells, but a low percentage of ...
G J, VANHOOSIER +3 more
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Lactoferricin enables adenovirus infection of human skeletal muscle cells
Abstract Although adenoviruses (AdVs) possess advantageous features as vectors, several challenges remain. These include a high prevalence of neutralizing antibodies against certain AdV types and the inability to efficiently transduce CAR-deficient cells and tissues.
Danskog, Katarina +6 more
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Epidemiological characteristics of human adenovirus infections in China, 2020–2023
To better understand the epidemiological characteristics of human adenovirus (HAdV) infections in China during and after the coronavirus disease 2019 (COVID-19) pandemic, respiratory specimens were collected from 17,562 enrolled patients with acute respiratory infections (ARIs) in 14 sentinel surveillance provinces during 2020-2023.
Chongyang Li +26 more
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