Results 81 to 90 of about 134,365 (335)
Regulation of prokaryotic adenylyl cyclases by CO2 [PDF]
Biochemical Journal, 2006 The Slr1991 adenylyl cyclase of the model prokaroyte Synechocystis PCC 6803 was stimulated 2-fold at 20 mM total Ci (inorganic carbon) at pH 7.5 through an increase in kcat. A dose response demonstrated an EC50 of 52.7 mM total Ci at pH 6.5. Slr1991 adenylyl cyclase was activated by CO2, but not by HCO3−.
Hammer, A. +2 more
openaire +5 more sources
Andrology, EarlyView.Abstract Background and objectives Epididymal transit renders key competence to mammalian spermatozoa for fertilizing eggs. Generally, the two paralogs of glycogen synthase kinase 3, GSK3α and GSK3β, functionally overlap except in testis and sperm. We showed that GSK3α is essential for epididymal sperm maturation and fertilization.
Mustfa Kabi +5 more
wiley +1 more source
ADENYLYL CYCLASE ASSAYS TO MEASURE MACROPHAGE CHEMOTACTIC PROTEIN-1 RECEPTOR FUNCTION
Iranian Journal of Allergy, Asthma and Immunology, 2000 Adenylyl cyclase is a membrane-bound enzyme that catalyzes the conversion of ATP to cAMP. The inhibition of adenylyl cyclase was carried out by measuring the ability of the macrophage chemotactic protein-1 to inhibit the torskolin-induced enzyme activity.
Durdi Qujeq +1 more
doaj
Frontiers in Pharmacology, 2022 Opioid tolerance, opioid-induced hyperalgesia during repeated opioid administration, and chronic pain are associated with upregulation of adenylyl cyclase activity.
Kayla Johnson +8 more
doaj +1 more source
Luteinizing hormone receptor knockout mouse: What has it taught us?
Andrology, EarlyView.Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley +1 more source
Place learning overrides innate behaviors in Drosophila [PDF]
, 2018 Animals in a natural environment confront many sensory cues. Some of these cues bias behavioral decisions independent of experience, and action selection can reveal a stimulus–response (S–R) connection.
Baggett, Vincent +5 more
core +2 more sources
British Journal of Pharmacology, EarlyView.Background and Purpose The pattern recognition receptors, formyl peptide receptors, FPR1 and FPR2, are G protein‐coupled receptors that recognize many different pathogen‐ and host‐derived ligands. While FPR1 conveys pro‐inflammatory signals, FPR2 is linked with pro‐resolving outcomes.
Denise Pajonczyk +5 more
wiley +1 more source
The role of mislocalized phototransduction in photoreceptor cell death of retinitis pigmentosa.
PLoS ONE, 2012 Most of inherited retinal diseases such as retinitis pigmentosa (RP) cause photoreceptor cell death resulting in blindness. RP is a large family of diseases in which the photoreceptor cell death can be caused by a number of pathways.
Takeshi Nakao +4 more
doaj +1 more source
Opioid receptors in cardiovascular function
British Journal of Pharmacology, EarlyView.Opioid receptors are G protein‐coupled receptors expressed by various cells in the heart, including myocytes and nerve fibres, and play a crucial role in modulating cardiac function. These receptors influence neural transmission, heart rate and myocyte contractility, offering cardioprotection.
Venkatesh Katari +4 more
wiley +1 more source
Mediators of Inflammation, 1993 Alveolar macrophages have recently been postulated as being involved in the aetiology of adult respiratory distress syndrome (ARDS). To evaluate their role, basal cyclic AMP levels and responsiveness of adenylyl cyclase alveolar macrophages were ...
J. G. C. van Amsterdam +3 more
doaj +1 more source