Results 61 to 70 of about 36,489 (201)

Cell signalling in Paracoccidioides Brasiliensis [PDF]

, 2006
Paracocidioides brasiliensis (P. brasiliensis or Pb) is the etiological agent of paracocidioidomycosis which is the most prevalent systemic mycosis in South America.
Chen, Daliang
core  

6‐Nitrodopamine as a Novel Mediator of Prostatic Smooth Muscle Function in Mouse and Human

Andrology, EarlyView.
ABSTRACT Background Epithelium‐derived catecholamines contribute to local regulation of genitourinary smooth muscle function, but the role of the endogenous 6‐nitrodopamine (6‐ND) in the prostate remains unknown. Objectives To determine whether 6‐ND is produced by mouse and human prostate and its role in smooth muscle regulation.
Alline Araujo Curiel, Fabio Henrique da Silva, Jéssica Mariana Dias, Luise Gabriela Santos Pereira, Douglas Rafael Martins Dias, Amanda Bueno Olivotti, André Almeida Schenka, Valéria Barbosa de Souza, Masato Tsutsui, Fabiola Zakia Monica, Edson Antunes, Gilberto De Nucci, Mariana G. de Oliveira   +12 more
wiley   +1 more source

Pulmonary granulocyte influx and impaired alveolar macrophage adenylyl cyclase responsiveness in developing respiratory distress

Mediators of Inflammation, 1993
Alveolar macrophages have recently been postulated as being involved in the aetiology of adult respiratory distress syndrome (ARDS). To evaluate their role, basal cyclic AMP levels and responsiveness of adenylyl cyclase alveolar macrophages were ...
J. G. C. van Amsterdam, R. M. J. L. van der Heijde, H. P. Grotjohan, F. D. Beusenberg   +3 more
doaj   +1 more source

The role of mislocalized phototransduction in photoreceptor cell death of retinitis pigmentosa.

PLoS ONE, 2012
Most of inherited retinal diseases such as retinitis pigmentosa (RP) cause photoreceptor cell death resulting in blindness. RP is a large family of diseases in which the photoreceptor cell death can be caused by a number of pathways.
Takeshi Nakao, Motokazu Tsujikawa, Shoji Notomi, Yasuhiro Ikeda, Kohji Nishida   +4 more
doaj   +1 more source

Intracellular cAMP Signaling Pathway via G_s Protein-Coupled Receptor Activation in Rat Primary Cultured Trigeminal Ganglion Cells

Biomedicines, 2023
G protein-coupled receptors in trigeminal ganglion (TG) neurons are often associated with sensory mechanisms, including nociception. We have previously reported the expression of P2Y12 receptors, which are Gi protein-coupled receptors, in TG cells ...
Yuki Kunioku, Maki Kimura, Takehito Ouchi, Kenichi Fukuda, Yoshiyuki Shibukawa   +4 more
doaj   +1 more source

Isoform-dependent activation of adenylyl cyclase by proteolysis [PDF]

, 1997
Recent findings have suggested that the cellular proteolytic system plays a major role in the regulation of various intra- and extra-cellular signaling.
Jun-ichi Kawabe, Naoki Oka, Toya, Yoshiyuki, Yoshihiro Ishikawa, Ebina, Toshiaki, Carsten Schwencke, Kawabe, Jun-ichi, Oka, Naoki, Schwencke, Carsten, Ishikawa, Yoshihiro, Toshiaki Ebina, Yoshiyuki Toya   +11 more
core   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Cyclic AMP signalling in pancreatic islets [PDF]

, 2010
Cyclic 3'5'AMP (cAMP) is an important physiological amplifier of glucose-induced insulin secretion by the pancreatic islet β-cell, where it is formed by the activity of adenylyl cyclases, which are stimulated by glucose, through elevation in ...
Nigel J. Pyne, Pyne, Nigel J., Brian Furman, Wee Kiat Ong, Furman, Brian L., Ong, Wee Kiat, Ong, W.K., Furman, Brian   +7 more
core   +2 more sources

Effects of chlorogenic acid on carbachol-induced contraction of mouse urinary bladder

Journal of Pharmacological Sciences, 2018
Chlorogenic acid (CGA) is a polyphenol found in coffee and medicinal herbs such as Lonicera japonica. In this study, the effect of CGA-induced relaxation on carbachol (CCh)-induced contraction of mouse urinary bladder was investigated. CGA (30–300 μg/ml)
Takeharu Kaneda, Noriyasu Sasaki, Norimoto Urakawa, Kazumasa Shimizu   +3 more
doaj   +1 more source

Effets d'un traitement chronique par la morphine sur le protéome des cellules de neuroblastome humain SH-SY5Y [PDF]

, 2007
Afin de mieux comprendre les adaptations cellulaires induites suite à une prise chronique de morphine, une stratégie de type protéomique différentielle combinant les techniques d'électrophorèse et de spectrométrie de masse a été entreprise dans des ...
Mouledous, Lionel
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