Results 51 to 60 of about 36,489 (201)
Molecular cloning of the human type VIII adenylyl cyclase [PDF]
, 1994 A cDNA coding for a human type VIII adenylyl cyclase has been isolated from human newborn brain-stem tissue. This cDNA is 6,005 bp long and encodes for a protein of 1251 amino acids, exhibiting the two sets of six transmembrane spanning regions and the ...
Alena Danisova +15 more
core +1 more source
The regulation of the cAMP signalling pathway in the human pathogenic fungus Paracoccidioides brasiliensis [PDF]
, 2008 Paracoccidioides brasiliensis (Pb) is the causative agent of the disease Paracoccioidomycosis (PCM), which is one of the most prevalent systemic mycoses in Latin Amercia (Borges-Walmsley et al., 2002). P.
Janganan, Thamarai kannan
core
CAP1 binds and activates adenylyl cyclase in mammalian cells
, 2021 CAP1 (Cyclase-Associated Protein 1) is highly conserved in evolution. Originally identified in yeast as a bifunctional protein involved in Ras-adenylyl cyclase and F-actin dynamics regulation, the adenylyl cyclase component seems to be lost in mammalian ...
Pizzoni, Alejandro (author) +6 more
core +1 more source
ADENYLYL CYCLASE ASSAYS TO MEASURE MACROPHAGE CHEMOTACTIC PROTEIN-1 RECEPTOR FUNCTION
Iranian Journal of Allergy, Asthma and Immunology, 2000 Adenylyl cyclase is a membrane-bound enzyme that catalyzes the conversion of ATP to cAMP. The inhibition of adenylyl cyclase was carried out by measuring the ability of the macrophage chemotactic protein-1 to inhibit the torskolin-induced enzyme activity.
Durdi Qujeq +1 more
doaj
PLoS Pathogens, 2022 There is a growing appreciation for the idea that bacterial utilization of host-derived lipids, including cholesterol, supports Mycobacterium tuberculosis (Mtb) pathogenesis.
Kaley M Wilburn +10 more
doaj +1 more source
Regulation of adenylyl and quanylyl cyclase in Dictyostelium discoideum [PDF]
, 1998 This thesis presents a number of studies of the molecular components that form the core of signal transduction in the social amoeba Dictyostelium discoideum. ...
Valkema, Romkje, Valkema, Romkje,
core
Requirement of Drosophila NF1 for activation of adenylyl cyclase by PACAP38-like neuropeptides
, 1997 The human neurofibromatosis type 1 (NF1) tumor suppressor protein functions as a Ras-specific guanosine triphosphatase-activating protein, but the identity of Ras- mediated pathways modulated by NF1 remains unknown.
Hui-fu Guo +9 more
core +1 more source
Identification of Novel Interacting Proteins of FUZ and GPR161
PROTEOMICS, EarlyView.ABSTRACT Protein–protein interactions are central to the dynamic regulation of signaling pathways and provide critical insight into the cellular mechanisms underlying human disease. Our previous study demonstrated biochemical and genetic interactions between FUZ and GPR161 in sonic hedgehog signaling during spinal neural tube development. In this study,
Gabriella Salazar +3 more
wiley +1 more source
Characterization of signalling cross-talk between the EP2 and FP receptors in endometrial epithelial cells [PDF]
, 2009 Uterine fibroids are benign tumors that arise from the smooth-muscle uterine cells (myometrium) and are the most common uterine disorder occurring in as many as 30% of women over 35 years of age. Despite their frequent occurrence, the etiology of uterine
Abera, Aron Berhanie
core +1 more source
Sensory Neuroscience, EarlyView.Glaucoma is increasingly understood as a neurodegenerative disorder shaped by sleep and circadian physiology, not intraocular pressure alone. Sleep loss and obstructive sleep apnea suppress BDNF–TrkB neurotrophic signaling, impair sleep‐dependent glymphatic clearance, and trigger microglial neuroinflammation and vascular insult at the optic nerve head,
Karyme M. Alemán‐Villa +5 more
wiley +1 more source