Results 41 to 50 of about 84,347 (233)

Simultaneous stimulation of GABA and beta adrenergic receptors stabilizes isotypes of activated adenylyl cyclase heterocomplex

BMC Cell Biology, 2004
Background We investigated how the synthesis of cAMP, stimulated by isoproterenol acting through β-adrenoreceptors and Gs, is strongly amplified by simultaneous incubation with baclofen.
Robichon Alain, Tinette Sylvette, Courtial Cédric, Pelletier Franck   +3 more
doaj   +1 more source

Facilitated G protein coupling to adenylyl cyclase as a mechanism of antidepressant action.

, 1995
Facilitated G protein coupling to adenylyl cyclase as a mechanism of antidepressant ...
Jiang. Chen (8000519)
core   +5 more sources

CAP1 binds and activates adenylyl cyclase in mammalian cells

, 2021
CAP1 (Cyclase-Associated Protein 1) is highly conserved in evolution. Originally identified in yeast as a bifunctional protein involved in Ras-adenylyl cyclase and F-actin dynamics regulation, the adenylyl cyclase component seems to be lost in mammalian ...
Pizzoni, Alejandro (author), Altschuler, Daniel L. (author), Naim, Nyla (author), Korkhov, Volodymyr (author), Qi, Chao (author), Zhang, Xuefeng (author), Hong, Kyoungja (author)   +6 more
core   +1 more source

The effect of tubulin in the regulation of adenylyl cyclase.

, 1991
The effect of tubulin in the regulation of adenylyl ...
Kun. Yan (7963124)
core   +3 more sources

Interactions Between Insulin and Adenylyl Cyclase Signalling [PDF]

, 1993
Hepatocytes immortalised by transfection with SV40 viral DNA have been well studied with respect to marker protein expression and the effects of immortalisation on cell phenotype.
Livingstone, Callum
core   +6 more sources

CO(2) acts as a signalling molecule in populations of the fungal pathogen Candida albicans. [PDF]

, 2010
When colonising host-niches or non-animated medical devices, individual cells of the fungal pathogen Candida albicans expand into significant biomasses. Here we show that within such biomasses, fungal metabolically generated CO(2) acts as a communication
Topal Hüsnü, Maccallum, Donna M., Hall, Rebecca, Fritz A. Mühlschlegel, Gow, Neil A R, Hall, Rebecca A., Rebecca A Hall, Bloor, JW, Bloor James W., Neil A. R. Gow, Steegborn Clemens, James W, Bloor, James W., Muehlschlegel, Fritz A, Rebecca A. Hall, Buck, Jochen, Hall, RA, Wang Yue, Gow, Neil A. R., Hüsnü Topal, Hall Rebecca A., Buck Jochen, Fritz A Mühlschlegel, Eaton Rebecca, Wang, Yue, Donna M. Maccallum, Mühlschlegel Fritz A., MacCallum, Donna M, De Sordi, Luisa, Levin Lonny R., Gary K Robinson, Jochen Buck, Maccallum, DM, James W. Bloor, Steegborn, Clemens, Neil A R Gow, Topal, Husnu, Mühlschlegel, Fritz A, MacCallum Donna M., Eaton, R, De Sordi, L, Levin, LR, Gary K. Robinson, Steegborn, C, Rebecca Eaton, Luisa De Sordi, Mühlschlegel, FA, Clemens Steegborn, Robinson, GK, Lonny R Levin, Mühlschlegel, Fritz A., De Sordi Luisa, Wang, Y, Levin, Lonny R., Gow Neil A. R., Donna M Maccallum, Levin, Lonny R, Topal, Huesnue, Topal, H, Robinson, Gary K, Gow, NA, Lonny R. Levin, Eaton, Rebecca, James W Bloor, Hall, Rebecca; id_orcid, Bloor, James W, Robinson Gary K., Buck, J, Yue Wang, Robinson, Gary K., Robinson G.K., de Sordi L., MacCallum D.M., Wang Y., Bloor J.W., Topal H., Steegborn C., Mühlschlegel F.A., Levin L.R., Gow N.A.R., Eaton R., Buck J., Hall R.A.   +82 more
core   +1 more source

Rhodopsin-cyclases for photocontrol of cGMP/cAMP and 2.3 Å structure of the adenylyl cyclase domain

Nature Communications, 2018
Cyclic AMP and cGMP orchestrate a variety of cellular responses. Here, authors characterize the cGMP producing rhodopsin-guanylyl cyclase from C. anguillulae and derived adenylyl cyclase by a biochemical and structural approach which demonstrates the ...
Ulrike Scheib, Matthias Broser, Oana M. Constantin, Shang Yang, Shiqiang Gao, Shatanik Mukherjee, Katja Stehfest, Georg Nagel, Christine E. Gee, Peter Hegemann   +9 more
doaj   +1 more source

Reduced activity of adenylyl cyclase 1 attenuates morphine induced hyperalgesia and inflammatory pain in mice

Frontiers in Pharmacology, 2022
Opioid tolerance, opioid-induced hyperalgesia during repeated opioid administration, and chronic pain are associated with upregulation of adenylyl cyclase activity.
Kayla Johnson, Alexis Doucette, Alexis Edwards, Aleeya Verdi, Ryan McFarland, Shelby Hulke, Amanda Fowler, Val J. Watts, Amanda H. Klein   +8 more
doaj   +1 more source

l-DOPA-induced dyskinesia in hemiparkinsonian rats is associated with up-regulation of adenylyl cyclase type V/VI and increased GABA release in the substantia nigra reticulata

Neurobiology of Disease, 2011
l-DOPA treatment induces abnormal involuntary movements (AIMs) in Parkinson's patients and experimental animals. We examined the relationship between the development of AIMs (dyskinesia) and changes in [3H]-GABA release and cAMP signaling in ...
Claudia Rangel-Barajas, Isaac Silva, Luz María Lopéz-Santiago, Jorge Aceves, David Erlij, Benjamín Florán   +5 more
doaj   +1 more source

Pulmonary granulocyte influx and impaired alveolar macrophage adenylyl cyclase responsiveness in developing respiratory distress

Mediators of Inflammation, 1993
Alveolar macrophages have recently been postulated as being involved in the aetiology of adult respiratory distress syndrome (ARDS). To evaluate their role, basal cyclic AMP levels and responsiveness of adenylyl cyclase alveolar macrophages were ...
J. G. C. van Amsterdam, R. M. J. L. van der Heijde, H. P. Grotjohan, F. D. Beusenberg   +3 more
doaj   +1 more source