Results 41 to 50 of about 33,547 (160)
Biomedicines, 2023 G protein-coupled receptors in trigeminal ganglion (TG) neurons are often associated with sensory mechanisms, including nociception. We have previously reported the expression of P2Y12 receptors, which are Gi protein-coupled receptors, in TG cells ...
Yuki Kunioku +4 more
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Effects of chlorogenic acid on carbachol-induced contraction of mouse urinary bladder
Journal of Pharmacological Sciences, 2018 Chlorogenic acid (CGA) is a polyphenol found in coffee and medicinal herbs such as Lonicera japonica. In this study, the effect of CGA-induced relaxation on carbachol (CCh)-induced contraction of mouse urinary bladder was investigated. CGA (30–300 μg/ml)
Takeharu Kaneda +3 more
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Stimulatory effects of adenosine on prolactin secretion in the pituitary gland of the rat
Brazilian Journal of Medical and Biological Research, 2002 We investigated the effects of adenosine on prolactin (PRL) secretion from rat anterior pituitaries incubated in vitro. The administration of 5-N-methylcarboxamidoadenosine (MECA), an analog agonist that preferentially activates A2 receptors, induced a ...
D.L.W. Picanço-Diniz +3 more
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Toxins, 2019 Myeloid phagocytes have evolved to rapidly recognize invading pathogens and clear them through opsonophagocytic killing. The adenylate cyclase toxin (CyaA) of Bordetella pertussis and the edema toxin (ET) of Bacillus anthracis are both calmodulin ...
Shakir Hasan +3 more
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Induction of RAGE shedding by activation of G protein-coupled receptors. [PDF]
PLoS ONE, 2012 The multiligand Receptor for Advanced Glycation End products (RAGE) is involved in various pathophysiological processes, including diabetic inflammatory conditions and Alzheimers disease.
Verena V Metz +3 more
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Journal of Pharmacological Sciences, 2004 We previously reported that sphingosine 1-phosphate (S1P) induces inhibition of adenylyl cyclase and activation of phospholipase C via independent G protein-coupled receptors in adult rat hepatocytes.
Dong-Soon Im +4 more
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Bicarbonate Stimulated Adenylyl Cyclases [PDF]
IUBMB Life, 2004 AbstractBicarbonate ion is fundamental to the biology of all living organisms. HCO3‐ is vital to such diverse physiological processes as carbon fixation, cellular homeostasis, sperm maturation, and nucleotide synthesis. A defined subset of adenylyl cyclases identified in eukaryotes and prokaryotes are directly activated by HCO3‐.
openaire +2 more sources
Dop1 enhances conspecific olfactory attraction by inhibiting miR-9a maturation in locusts
Nature Communications, 2018 Migratory locusts shift between aggregating together during gregarious phases and living individually during solitary phases. Here, the authors find that the D1-like dopamine receptor regulates the olfactory attraction underlying this behavioral switch ...
Xiaojiao Guo +7 more
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Soluble adenylyl cyclase in the eye
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2014 Adenylyl cyclases (ACs) are a family of enzymes which convert ATP to cAMP, an essential intermediate in many signal transduction pathways. Of the 10 AC genes in man, 9 fall into the category of transmembrane ACs (tmACs), which associate with G-protein coupled receptors (GPCRs) and are activated by forskolin.
Lee, Yong S. +2 more
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PLoS ONE, 2019 PurposeWe previously reported that inhibitory G protein (Gi) exerts intrinsic receptor-independent inhibitory activity upon adenylyl cyclase (AC) that regulates contractile force in rat ventricle. The two major subtypes of AC in the heart are AC5 and AC6.
Caroline Bull Melsom +9 more
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