Results 41 to 50 of about 5,329 (178)

A Biofunctional Hydrogel/Nanofiber Bilayer Scaffold Delivering EGF and TGFβ3 for Advanced Nasal Tissue Reconstruction

open access: yesMacromolecular Materials and Engineering, Volume 310, Issue 12, December 2025.
This study develops a biomimetic bilayer scaffold based on gelatin methacryloyl‐ciprofloxacin/polycaprolactone‐collagen (GelMA‐CIP/PCL‐COL), designed to release EGF and TGFβ3 in a controlled manner. The GelMA‐CIP@PVA‐EGF/PCL‐COL@PVA‐TGFβ3 scaffold currently demonstrates sustained delivery of growth factors for 28 days, mechanical properties similar to ...
Hilal Yilmaz   +11 more
wiley   +1 more source

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

open access: yesMolecular Oncology, Volume 19, Issue 9, Page 2557-2573, September 2025.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo   +11 more
wiley   +1 more source

Sol-gel synthesis of zirconia-based nanoparticles from the side product of tin mining [PDF]

open access: yesE3S Web of Conferences
Indonesia has been one of the world’s primary source of tin since the early of 19th century. Bangka island has the largest tin abundant with a side product is zircon sand (ZrSiO4).
Kristiani Anis   +9 more
doaj   +1 more source

Ultrathin (<10 nm) Electrochemical Random‐Access Memory that Overcomes the Tradeoff between Robust Weight Update and Speed in Neuromorphic Systems

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 8, August 2025.
To address the tradeoff between synaptic linearity and operating speed, a Cu ion‐based ultrathin electrochemical random‐access memory is engineered using a 1.2 nm AlOx liner and 5 nm HfOx layer. The device exhibits fast and uniform weight updates under 50 μs pulses, along with long retention and high endurance, paving the way for robust synaptic units ...
Seonuk Jeon   +3 more
wiley   +1 more source

Mechanistic Insights and Pharmacological Approaches for Nitrogen and Sulfur Mustards and Their Implications as Therapeutic Agents

open access: yesJournal of Applied Toxicology, Volume 45, Issue 8, Page 1417-1425, August 2025.
ABSTRACT Nitrogen and sulfur mustards, often acting as vesicants, have significant consequences for public health. Skin is a common site for exposure to these vesicants that can result in considerable morbidity and mortality. Given that the treatment options are limited, new insights into the mechanisms for the toxicity of these vesicants that can be ...
Madison Owens   +3 more
wiley   +1 more source

Itinéraire du paysan notaire de Bechir Madet ou l’écriture de l’autobiographie par procuration

open access: yesAkofena
Résumé : Cet article s’appuie sur la poétique autobiographique de Philippe Lejeune et met à l’épreuve les critères énumérés et théorisés dans Le pacte autobiographique (1975).
Emmanuel KALPET, MOURSAL MAKAYE & Félix ASGUET MAH
doaj   +1 more source

Toward a Deterministic Model of Planetary Formation IV: Effects of Type-I Migration

open access: yes, 2007
In a further development of a deterministic planet-formation model (Ida & Lin 2004), we consider the effect of type-I migration of protoplanetary embryos due to their tidal interaction with their nascent disks.
D. N. C. Lin   +6 more
core   +2 more sources

Zinc Chalcogenide Based Shell Layers for Colloidal Quantum Wells

open access: yesAdvanced Materials Interfaces, Volume 12, Issue 12, June 23, 2025.
A new synthetic route is developed for the synthesis of CdSe/ZnSe/ZnS multi‐shell nanoplatelets (NPLs) with emissions between 615 and 630 nm and photoluminescence quantum yields up to 90%. Control over the lateral size of the starting CdSe core enabled the narrowing of the emission linewidth to 20 nm.
Cagatay Han Aldemir   +5 more
wiley   +1 more source

La première valeur propre de l'opérateur de Dirac sur les variétés kählériennes compactes [PDF]

open access: yes, 1995
International audienceK.D. Kirchberg gave a lower bound for the first eigenvalue of the Dirac operator on a spin compact Kähler manifoldM of odd complex dimension with positive scalar curvature.
Moroianu, Andrei
core   +2 more sources

Identification of a phenyl ester covalent inhibitor of caseinolytic protease and analysis of the ClpP1P2 inhibition in mycobacteria

open access: yesmLife, Volume 4, Issue 2, Page 155-168, April 2025.
Abstract The caseinolytic protease complex ClpP1P2 is crucial for protein homeostasis in mycobacteria and stress response and virulence of the pathogens. Its role as a potential drug target for combating tuberculosis (TB) has just begun to be substantiated in drug discovery research.
Genhui Xiao   +12 more
wiley   +1 more source

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