Results 1 to 10 of about 13,032 (201)
Mitochondrial Protease ClpP: Cancer Marker and Drug Target
PharmaceuticalsBackground: The human mitochondrial ClpP is a serine protease located in the mitochondrial matrix responsible for degrading short lived regulatory proteins as well as misfolded or damaged proteins, thereby maintaining cellular homeostasis.
Savina Ferorelli +2 more
exaly +6 more sources
Effects of ClpP protease on biofilm formation of Enterococcus faecalis [PDF]
Journal of Applied Oral Science, 2021 Enterococcus faecalis (E. faecalis), one of the main pathogens responsible for refractory periapical periodontitis and nosocomial infections, exhibits markedly higher pathogenicity in biofilms. Objectives Studies have shown that caseinolytic protease P
Ying FENG +4 more
doaj +7 more sources
Mitochondrial Stress Response Gene Clpp Is Not Required for Granulosa Cell Function
Antioxidants, 2020 Mitochondrial unfolded protein response (UPRmt) is a highly conserved mechanism, which is activated upon cellular or metabolic stress and aims to help cells maintain homeostasis.
Ecem Esencan +3 more
doaj +2 more sources
Virulence, 2022 The resistance of Staphylococcus aureus (S. aureus) to various antibiotics has increased dramatically due to the misuse of antibiotics, and thus the development of new anti-infective drugs with new targets is urgently needed to combat resistance ...
Shisong Jing +12 more
doaj +2 more sources
Bacterial ClpP Protease Is a Potential Target for Methyl Gallate [PDF]
Frontiers in Microbiology, 2021 Methyl gallate (MG) is an effective microbicide with great potential application in the integrated management of plant diseases and an important potential drug for clinical application. However, its target remains unknown.
Dehong Zheng +4 more
doaj +3 more sources
ClpP regulates breast cancer cell proliferation, invasion and apoptosis by modulating the Src/PI3K/Akt signaling pathway [PDF]
PeerJ, 2020 Background Caseinolytic protease P (ClpP), which is located on the inner mitochondrial membrane, degrades mitochondrial proteins damaged by oxidative stress. The role of ClpP varies among tumor types.
Juan Luo +4 more
doaj +3 more sources
The ClpP protease is required for the stress tolerance and biofilm formation in Actinobacillus pleuropneumoniae. [PDF]
PLoS ONE, 2013 In the respiratory tract and lung tissue, a balanced physiological response is essential for Actinobacillus pleuropneumoniae to survive various types of challenges.
Fang Xie +5 more
doaj +2 more sources
Modeling and Simulation of Dissemination of Cultivated Land Protection Policies in China
Land, 2021 Cultivated land protection is the top priority of the national economy in China and the livelihood of people. Cultivated land protection policies (CLPP) play an important role in the protection of cultivated land. However, the process of dissemination of
Xinhai Lu, Yanwei Zhang, Handong Tang
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Soil Microbial Activity and Diversity in Response to Soil Chemical Factors in Agricultural Soils
Journal of Tropical Soils, 2019 The role of microbial communities in maintaining soil health is mostly influenced by chemical condition of soil. Microbial communities vary in response to soil chemical factors.
Lily Ishak, Philip Hugh Brown
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Ecological Indicators, 2021 The evaluation of the effects of cultivated land protection policies (CLPP) is an important issue in China’s food security and land policy regulation. This article first analyzes the historical evolution of CLPP in China and divides it into five stages ...
Xinhai Lu, Yanwei Zhang, Yucheng Zou
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