Results 1 to 10 of about 4,619 (182)

Prediction of extracellular proteases of the human pathogen Helicobacter pylori reveals proteolytic activity of the Hp1018/19 protein HtrA.

PLoS ONE, 2008
Exported proteases of Helicobacter pylori (H. pylori) are potentially involved in pathogen-associated disorders leading to gastric inflammation and neoplasia. By comprehensive sequence screening of the H. pylori proteome for predicted secreted proteases,
Martin Löwer, Christiane Weydig, Dirk Metzler, Andreas Reuter, Anna Starzinski-Powitz, Silja Wessler, Gisbert Schneider   +6 more
doaj   +1 more source

Thrombolytic protease characterization from leaves and fruit flesh of the jernang rattan plant (Daemonorops draco)

Indonesian Journal of Biotechnology, 2023
Thrombolytic agents are used for thrombolytic therapy to dissolve blood clots that form in a blood vessel. All currently used thrombolytic agents have unfavorable shortcomings, such as gastrointestinal bleeding, allergic reactions, and thrombolytic agent
Urbanus Yustus Lebuan, Roga Florida Kembaren, Merry Meryam Martgrita, Cut Rizlani Kholibrina   +3 more
doaj   +1 more source

Specific Activation of K-RasG12D Allele in the Bladder Urothelium Results in Lung Alveolar and Vascular Defects [PDF]

, 2014
K-ras is essential for embryogenesis and its mutations are involved in human developmental syndromes and cancer. To determine the consequences of K-ras activation in urothelium, we used uroplakin-II (UPK II) promoter driven Cre recombinase mice and ...
Ayala de la Peña, Francisco, Kalluri, Raghu, Kanasaki, Keizo, Kanasaki, Megumi, Rovira, Carlota, Vong, Sylvia   +5 more
core   +10 more sources

Proteomic Analysis of Chloroplast-to-Chromoplast Transition in Tomato Reveals Metabolic Shifts Coupled with Disrupted Thylakoid Biogenesis Machinery and Elevated Energy-Production Components [PDF]

, 2012
A comparative proteomic approach was performed to identify differentially expressed proteins in plastids at three stages of tomato(Solanum lycopersicum) fruit ripening (mature-green, breaker, red). Stringent curation and processing of the data from three
Alba, Aldridge, Altschul, Andersson, Andon, Armbruster, Asano, Baginsky, Balmer, Bannai, Barry, Barsan, Benjamini, Benning, Bian, Birtić, Blanke, Booth, Botella-Pavía, Bouvier, Bouyssié, Bramley, Bräutigam, Cai, Camara, Chen, Chen, Cho, Deborde, Delmar, Delmar, Demartini, Dieterle, Egea, Egea, Emanuelsson, Emes, Fan, Faurobert, Ferro, Fischer, Harris, Heazlewood, Heazlewood, Hetherington, Huang, Issaq, Jebanathirajah, Jeong, Jimenez, Kahlau, Kato, Kato, Kleffmann, Krech, Lee, Li, Li, Liu, Liu, Liu, Ljubesić, Lopez-Juez, Lundquist, Lytovchenko, Maple, Maple, Marano, McAndrew, Millar, Moing, Neta-Sharir, Niewiadomski, Onishi, Osorio, Palma, Paoletti, Pech, Peng, Pierleoni, Pirrello, Plücken, Ren, Richly, Rocco, Rutschow, Schauer, Seigneurin-Berny, Shipman-Roston, Siddique, Simkin, Small, Smith, Spurr, Su, Sun, Suzuki, Thelen, Thimm, Thomson, Tiwari, Torgrip, van Wijk, Vitha, von Zychlinski, Waters, Yakir-Tamang, Zeng, Zhang, Zhu, Zybailov   +110 more
core   +1 more source

Proteolytic and anti-proteolytic activity in the seminal plasma of Eurasian perch (Perca fluviatilis L.) during the spawning period

Czech Journal of Animal Science, 2011
The aim of this study was to describe possible changes in protease and anti-protease activity in the seminal plasma of European perch (Perca fluviatilis L.) during the spawning time.
J. Król, R. Kowalski, K. Demska-Zakęś, P. Hliwa, J. Glogowski   +4 more
doaj   +1 more source

Effect of oxidation, pH, and ionic strength on calpastatin inhibition of μ- and m-calpain [PDF]

, 2006
The objective of this study was to evaluate the effect of oxidation on μ- and m-calpain activity at varying pH and ionic strength conditions in the presence of calpastatin. In 2 separate experiments, purified porcine skeletal muscle μ- or m-calpain (0.45
Huff-Lonergan, Elisabeth, Huff-Lonergan, Elisabeth, Lonergan, Steven, Lonergan, Steven, Maddock Carlin, K., Rowe, L.   +5 more
core   +2 more sources

Caseinolytic mitochondrial matrix peptidase X is essential for homologous chromosome synapsis and recombination during meiosis of male mouse germ cells

Asian Journal of Andrology
Meiosis is the process of producing haploid gametes through a series of complex chromosomal events and the coordinated action of various proteins. The mitochondrial protease complex (ClpXP), which consists of caseinolytic mitochondrial matrix peptidase X
Hai-Wei Feng, Yu Zhao, Yan-Ling Gao, Dong-Teng Liu, Li-Jun Huo   +4 more
doaj   +1 more source

Novel Fibrinolytic Protease Producing Streptomyces radiopugnans VITSD8 from Marine Sponges

Marine Drugs, 2019
Fibrinolytic enzymes have received more attention due to their medicinal potential for thrombolytic diseases. The aim of this study is to characterize the in vitro fibrinolytic nature of purified protease producing Streptomyces radiopugnans VITSD8 from ...
Dhamodharan D, Jemimah Naine S, Merlyn Keziah S, Subathra Devi C   +3 more
doaj   +1 more source

Protease activity increases in plasma, peritoneal fluid, and vital organs after hemorrhagic shock in rats. [PDF]

PLoS ONE, 2012
Hemorrhagic shock (HS) is associated with high mortality. A severe decrease in blood pressure causes the intestine, a major site of digestive enzymes, to become permeable - possibly releasing those enzymes into the circulation and peritoneal space, where
Angelina E Altshuler, Alexander H Penn, Jessica A Yang, Ga-Ram Kim, Geert W Schmid-Schönbein   +4 more
doaj   +1 more source

Acyldepsipeptide Analogues: A Future Generation Antibiotics for Tuberculosis Treatment

Pharmaceutics, 2022
Acyldepsipeptides (ADEPs) are a new class of emerging antimicrobial peptides (AMPs), which are currently explored for treatment of pathogenic infections, including tuberculosis (TB). These cyclic hydrophobic peptides have a unique bacterial target to the
Sinazo Z. Z. Cobongela, Maya M. Makatini, Phumlane S. Mdluli, Nicole R. S. Sibuyi   +3 more
doaj   +1 more source