Results 41 to 50 of about 147,909 (161)

Structural insights into the inactive subunit of the apicoplast-localized caseinolytic protease complex of Plasmodium falciparum. [PDF]

J Biol Chem, 2013
The ATP-dependent caseinolytic protease, ClpP, is highly conserved in bacteria and in the organelles of different organisms. In cyanobacteria, plant plastids, and the apicoplast of the genus Plasmodium, a noncatalytic paralog of ClpP, termed ClpR, has been identified. ClpRs are found to form heterocomplexes with ClpP resulting in a ClpRP tetradecameric
El Bakkouri M, Rathore S, Calmettes C, Wernimont AK, Liu K, Sinha D, Asad M, Jung P, Hui R, Mohmmed A, Houry WA.   +10 more
europepmc   +4 more sources

The plastid caseinolytic protease complex as a model for cytonuclear coevolution

, 2021
Coevolution, or evolution in response to reciprocal selective pressures, is important to biological function and the persistence of populations. Competition or mutualisms between organisms can drive coevolution, as can predatory or parasitic relationships.
Williams, Alissa Marie, author, Sloan, Daniel, advisor, Bedinger, Patricia, committee member, Mueller, Rachel, committee member, Pilon, Marinus, committee member, Stenglein, Mark, committee member   +5 more
openaire   +1 more source

Bacterial caseinolytic proteases as novel targets for antibacterial treatment

International Journal of Medical Microbiology, 2014
Bacterial Clp proteases are important for protein turnover and homeostasis in order to maintain vital cellular functions particularly under stress conditions. Apart from their crucial role in general protein quality control by degrading abnormally folded or otherwise aberrant or malfunctioning proteins, their temporally and spatially precise ...
Heike, Brötz-Oesterhelt, Peter, Sass
openaire   +2 more sources

ClpB is an essential stress regulator of Mycobacterium tuberculosis and endows survival advantage to dormant bacilli

International Journal of Medical Microbiology, 2020
The ability to tolerate multiple host derived stresses, resist eradication and persist within the infected individuals is central to the pathogenicity of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB).
Prajna Tripathi, Lalit K. Singh, Sujata Kumari, Owais R. Hakiem, Janendra K. Batra   +4 more
doaj   +1 more source

Purification and physico-chemical properties of Bacillus atrophaeus protease with elastolytic and fibrinogenolytic activity [PDF]

The Ukrainian Biochemical Journal
Microbial proteases, among which proteases capable of cleaving elastin, fibrin, fibrinogen, and collagen, have been a matter of interest to researchers due to their significant biotechnological potential along with low production cost.
O. V. Gudzenko, L. D. Varbanets, V. O. Chernyshenko, Y. M. Stohnii, A. M. Ostapchuk, V. O. Ivanytsia   +5 more
doaj   +1 more source

Plasma and peritoneal fluid caseinolytic activity.

, 2013
Caseinolytic activity with and without addition of a serine protease inhibitor, 1 mM PMSF, of (A) plasma and (B) peritoneal fluid pre/post shock with saline or ANGD pre-treatment in the intestinal lumen.
Angelina E. Altshuler (328350), Alexander H. Penn (328351), Geert W. Schmid-Schönbein (317657), Jessica A. Yang (328352), Ga-Ram Kim (328353)   +4 more
core   +1 more source

Thrombolytic protease characterization from leaves and fruit flesh of the jernang rattan plant (Daemonorops draco)

Indonesian Journal of Biotechnology, 2023
Thrombolytic agents are used for thrombolytic therapy to dissolve blood clots that form in a blood vessel. All currently used thrombolytic agents have unfavorable shortcomings, such as gastrointestinal bleeding, allergic reactions, and thrombolytic agent
Urbanus Yustus Lebuan, Roga Florida Kembaren, Merry Meryam Martgrita, Cut Rizlani Kholibrina   +3 more
doaj   +1 more source

Proteolytic and anti-proteolytic activity in the seminal plasma of Eurasian perch (Perca fluviatilis L.) during the spawning period

Czech Journal of Animal Science, 2011
The aim of this study was to describe possible changes in protease and anti-protease activity in the seminal plasma of European perch (Perca fluviatilis L.) during the spawning time.
J. Król, R. Kowalski, K. Demska-Zakęś, P. Hliwa, J. Glogowski   +4 more
doaj   +1 more source

Caseinolytic mitochondrial matrix peptidase X is essential for homologous chromosome synapsis and recombination during meiosis of male mouse germ cells

Asian Journal of Andrology
Meiosis is the process of producing haploid gametes through a series of complex chromosomal events and the coordinated action of various proteins. The mitochondrial protease complex (ClpXP), which consists of caseinolytic mitochondrial matrix peptidase X
Hai-Wei Feng, Yu Zhao, Yan-Ling Gao, Dong-Teng Liu, Li-Jun Huo   +4 more
doaj   +1 more source

Protease activity increases in plasma, peritoneal fluid, and vital organs after hemorrhagic shock in rats. [PDF]

PLoS ONE, 2012
Hemorrhagic shock (HS) is associated with high mortality. A severe decrease in blood pressure causes the intestine, a major site of digestive enzymes, to become permeable - possibly releasing those enzymes into the circulation and peritoneal space, where
Angelina E Altshuler, Alexander H Penn, Jessica A Yang, Ga-Ram Kim, Geert W Schmid-Schönbein   +4 more
doaj   +1 more source