Results 51 to 60 of about 289,808 (311)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Otolaryngology Workforce Projections in the United States, 2021–2036

Laryngoscope Investigative Otolaryngology
Objective To analyze projections of otolaryngology workforce supply and demand in the U.S. from 2021 to 2036. Methods Otolaryngology workforce projection data from the Bureau of Health Workforce (BHW), Health Resources and Services Administration's (HRSA)
Lorik Berisha, Aman M. Patel, Alan Nguyen, Roshan V. Patel, Sapan M. Patel, Hassaam S. Choudhry, Rohini Bahethi, David W. Wassef, Paul T. Cowan, Ghayoour S. Mir, Andrey Filimonov   +10 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

國民中學適足教育經費：臺灣偏遠與非偏遠地區學校的比較 Estimating Adequate Funding to Meet Performance Standards for Junior High School Students: Adequate Funding Comparisons Between Rural and Non-Rural Schools in Taiwan

Journal of Research in Education Sciences, 2016
臺灣學生近年來在國際大型測驗表現亮眼，但如進一步檢視學校所處地區，即可明顯看出臺灣存在巨大的城鄉差距問題：偏遠地區與大城市相比，不僅數學表現較差，且出現各校數學差距相對較大的情況。不足的教育經費可能是導致此差距的原因之一，本研究因此以成本函數法來估算偏遠與非偏遠地區學校達成預期學生學業成就所需的適足經費，並以國中基測數學基礎級、平均數、精熟級來作為適足分數，以估算不同程度所需的適足經費，結果發現，無論何種適足分數，偏遠地區所需的每生適足經費皆比非偏遠地區為高，且超過半數以上的偏遠學校未達適足經費水準 ...
張良丞 Liang-Cheng Zhang, 許添明 Tian-Ming Sheu , 吳新傑Hsin-Chieh Wu   +2 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

On the Requirements of Legal Justice of the Administrative Law Enforcement Activity

Сибирское юридическое обозрение, 2020
The article considers issues of understanding by the administrative-legal science of legal justice of the law-enforcement activity of executive authorities, other public administration bodies.
S. V. Yarkovoy
doaj  

Estado nutricional e adequação da ingestão de energia e nutrientes em pacientes com insuficiência cardíaca Estado nutricional y adecuación de la ingesta de energía y nutrientes en pacientes con insuficiencia cardiaca Nutritional status and adequacy of energy and nutrient intakes among heart failure patients

Arquivos Brasileiros de Cardiologia, 2009
FUNDAMENTO: Maior conhecimento sobre o estado nutricional e a ingestão de energia e nutrientes é necessário para auxiliar no tratamento de pacientes com insuficiência cardíaca (IC).
Bárbara Hatzlhoffer Lourenço, Lis Proença Vieira, Alessandra Macedo, Miyoko Nakasato, Maria de Fátima Nunes Marucci, Edimar Alcides Bocchi   +5 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Influential predictors for financial adequacy among Malaysian public sector employees [PDF]

, 2015
Financially well employees are presumed to be portraying good work attitude and may result in good work performance. This will benefit their employer and organization. Knowing the adequateness level of their finances and what influence it is important as
Othman, Mohd Amim, Md Jusoh, Zuroni, Abdul Rahim @ Abdul Wahab, Husniyah, Sabri, Mohamad Fazli   +3 more
core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source