Force-dependent intercellular adhesion strengthening underlies asymmetric adherens junction contraction. [PDF]
Cavanaugh KE +7 more
europepmc +1 more source
Anaerobe‐Driven Inflammation and Epithelial Barrier Disruption in Genital HIV Acquisition
ABSTRACT Background Genital microbiome dysbiosis is an important risk factor for the sexual acquisition of human immunodeficiency virus (HIV) in both the male and female genital tracts. The vaginal, penile and urethral mucosae are distinct microenvironments with characteristic microbiome compositions.
Shirley Constable +6 more
wiley +1 more source
Multivalent interactions make adherens junction-cytoskeletal linkage robust during morphogenesis. [PDF]
Perez-Vale KZ +6 more
europepmc +1 more source
Graphical abstract illustrating the barrier defense–tolerance framework of reproductive innate immunity. Across the female and male reproductive tracts and the maternal–fetal interface, epithelial barriers, innate sensors, immune cells, and microbial signals are integrated to preserve reproductive homeostasis.
Xianlin Rao +3 more
wiley +1 more source
Adherens junction engagement regulates functional patterning of the cardiac pacemaker cell lineage. [PDF]
Thomas K +6 more
europepmc +1 more source
The Multifaceted Legacy of Thalidomide: Chemistry and Biology Driving Modern Drug Design
Thalidomide serves as a molecular nexus linking chemistry and biology: advances in synthesis and structural understanding enable protein degradation technologies, while its immunomodulatory activity underpins anti‐inflammatory and anticancer therapies.
Konstantina Nikovia +4 more
wiley +1 more source
Lasp1 regulates adherens junction dynamics and fibroblast transformation in destructive arthritis. [PDF]
Beckmann D +36 more
europepmc +1 more source
Paxillin promotes breast tumor collective cell invasion through maintenance of adherens junction integrity. [PDF]
Xu W, Alpha KM, Zehrbach NM, Turner CE.
europepmc +1 more source
Tissue fluidity mediated by adherens junction dynamics promotes planar cell polarity-driven ommatidial rotation. [PDF]
Founounou N +5 more
europepmc +1 more source
Beyond cell-cell adhesion: Emerging roles of the tight junction scaffold ZO-2 [PDF]
Gehwolf, R. +6 more
core +1 more source

