Results 171 to 180 of about 344,893 (256)

Protocol for fixation and staining of Drosophila melanogaster embryos optimized for DNA-PAINT nanoscopy of adherens junction proteins. [PDF]

STAR Protoc
Sharma N, Häring M, Richens JH, St Johnston D, Großhans J, Kong D.   +5 more
europepmc   +1 more source

DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy

MedComm, Volume 7, Issue 9, September 2026.
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu, Yuqin Jin, Baochao Li, Jie Deng, Yiwen Zhou, Jinglun Zhang, Huang Li   +6 more
wiley   +1 more source

Paths to stability - actin regulation of adherens junction mechanics. [PDF]

J Cell Sci
James J, Winn LBA, Mottram-Epson P, Köster D.   +3 more
europepmc   +1 more source

Paxillin promotes breast tumor collective cell invasion through maintenance of adherens junction integrity. [PDF]

Mol Biol Cell, 2022
Xu W, Alpha KM, Zehrbach NM, Turner CE.
europepmc   +1 more source

Adherens junction proteins in tumour progression

The loss of epithelial differentiation in carcinomas, which is accompanied by higher mobility and invasiveness of the tumour cells, is often a consequence of reduced intercellular adhesion.
Birchmeier, W., Behrens, J., Huelsken, J.   +2 more
core  

Immunoglobulin Kappa Light Chain Produced by Cardiomyocytes and Participates in Maintaining Intercalated Disc Integrity

MedComm, Volume 7, Issue 9, September 2026.
This study identifies Igκ expression in cardiomyocytes, with predominant localization at ICDs. Cardiomyocyte‐specific Igκ knockout induces cardiac dysfunction and ICDs structural disorganization. Mechanistically, Igκ stabilizes plectin to facilitate desmin‒actin network assembly and anchor desmin to DSP, which is critical for maintaining ICDs ...
Zhu Zhu, Yixuan Sheng, Yun Chang, Yuan Chang, Miaomiao Xu, Wenjing Zhou, Wenxiu Wang, Qingyuan Liao, Zhan Shi, Meng Zhang, Feng Lan, Jiangping Song, Xiaoyan Qiu   +12 more
wiley   +1 more source

NCKAP1 coordinates focal adhesion and adherens junction dynamics in endothelial barrier maintenance and angiogenesis. [PDF]

iScience
Xiao Y, Mendez PL, Hiepen C, Jatzlau J, Knaus P.   +4 more
europepmc   +1 more source

Tissue fluidity mediated by adherens junction dynamics promotes planar cell polarity-driven ommatidial rotation. [PDF]

Nat Commun, 2021
Founounou N, Farhadifar R, Collu GM, Weber U, Shelley MJ, Mlodzik M.   +5 more
europepmc   +1 more source

A simple probabilistic AlphaFold interaction score

Protein Science, Volume 35, Issue 9, September 2026.
Abstract AlphaFold has enabled large‐scale prediction of protein–protein and protein–nucleic acid complexes, but ranking and assessing the quality of predicted models remain challenging. Existing confidence scores are often highly parametrized and provide limited interpretability.
Mihaly Badonyi, Agnes Toth‐Petroczy
wiley   +1 more source

Adherens junction protein expression is associated with poor response to neoadjuvant FLOT chemotherapy and pro-inflammatory tumor microenvironment in esophageal adenocarcinoma. [PDF]

Int J Cancer
Grothey B, Löser H, Bedau T, Schröder W, Bruns CJ, Zander T, Krämer M, Büttner R, Quaas A.   +8 more
europepmc   +1 more source