Results 151 to 160 of about 51,811 (246)
Abstract INTRODUCTION The relationship between peripheral vascular health, including endothelia, cognitive decline, and Alzheimer's disease (AD) dementia risk is unclear. METHODS In this study, 2844 dementia‐free Framingham Offspring participants (mean age 60.6 years, 53.2% women) had baseline brachial artery flow‐mediated dilation (FMD%) and reactive ...
Qiushan Tao +15 more
wiley +1 more source
The complex of Fas-associated factor 1 with Hsp70 stabilizes the adherens junction integrity by suppressing RhoA activation. [PDF]
Song S +9 more
europepmc +1 more source
This study investigated airway epithelial barrier dysfunction persistence in ex‐smokers with COPD and underlying mechanisms using single‐cell RNA and ATAC sequencing. Epigenetic NKX2‐1/SPDEF dysregulation maintains goblet cell hyperplasia and barrier dysfunction despite long‐term smoking cessation.
Ayaka Shiota +17 more
wiley +1 more source
Letter by Horowitz Regarding Article, Protein Interactions at Endothelial Junctions and Signaling Mechanisms Regulating Endothelial Permeability . [PDF]
Horowitz, Arie
core +2 more sources
Adherens Junction Integrity Is a Critical Determinant of Sodium Iodide Symporter Residency at the Plasma Membrane of Thyroid Cells. [PDF]
Faria M +5 more
europepmc +1 more source
This study establishes a GeLC‐MS/MS‐based serum proteomics workflow for canine oral oncology to differentiate malignancies from non‐malignant conditions. Comprehensive protein profiling, pathway analysis and protein–drug interaction mapping reveal candidate biomarkers and insights into the pathogenesis of canine oral cancers.
Sekkarin Ploypetch +4 more
wiley +1 more source
Arvcf Dependent Adherens Junction Stability is Required to Prevent Age-Related Cortical Cataracts. [PDF]
Martin JB +5 more
europepmc +1 more source
ABSTRACT Spiders are renowned for their ecological versatility and silk‐based innovations in materials science, yet marine environments remain virtually uncolonized by this predominantly terrestrial lineage. A striking exception is the obligate intertidal spider genus Desis, whose members have evolved extraordinary physiological and behavioural ...
Fan Li +11 more
wiley +1 more source
Polychaetoid/ZO-1 strengthens cell junctions under tension while localizing differently than core adherens junction proteins. [PDF]
Schmidt A +8 more
europepmc +1 more source
Beyond the Barrier: Epithelial Cells as Immune Sentinels in the Female Genital Tract
ABSTRACT Epithelial cells (ECs) of the female genital tract (FGT) serve as an essential barrier and the first line of defense against sexually transmitted pathogens. Beyond providing a physical barrier, these cells actively contribute to immune responses through pathogen recognition, cytokine release, and modulation of adaptive immune responses ...
Lauren Jirik +3 more
wiley +1 more source

