Results 171 to 180 of about 52,251 (235)
ABSTRACT Intervertebral disc degeneration (IDD) can contribute to lower back and neck pain. In IDD, the most affected component of the intervertebral disc is the nucleus pulposus (NP). Derived from the notochord, where cells are organized into a tandem configuration, young NP cells cluster in three‐dimensional (3D) networks embedded in a gelatinous ...
Xiangyun Wei, Nam Vo, Gwendolyn A. Sowa
wiley +1 more source
Ageing causes actin cytoskeleton disorganization, a reduction in cellular components associated with the actin cytoskeleton and focal adhesions, and a reduction in skin firmness. Galactomyces ferment filtrate boosts actin stability, increases expression of anchoring junction proteins, including focal adhesions and protects against loss of firmness ...
Steph Crabtree +12 more
wiley +1 more source
The Subgingival Host–Microbial Landscape in Mothers With Periodontitis and Their At‐Risk Offspring
ABSTRACT Aim To evaluate the subgingival proteome and microbiome of mothers with periodontitis and their offspring, thereby assessing signatures of periodontal diseases. Methods Forty participants in four groups were included: mothers with periodontitis and their offspring, as well as periodontally healthy mothers and their offspring.
Hélvis E. S. Paz +8 more
wiley +1 more source
Sirt3 Maintains Microvascular Endothelial Adherens Junction Integrity to Alleviate Sepsis-Induced Lung Inflammation by Modulating the Interaction of VE-Cadherin and β-Catenin. [PDF]
Chen DQ +8 more
europepmc +1 more source
ABSTRACT The choroid plexus (CP) contributes to cerebrospinal fluid (CSF) production and regulation of circadian rhythm. Recently, many neuroimaging studies have reported enlarged CP volumes in patients with neurodegenerative diseases, including Alzheimer's disease (AD).
Ryuta Murakami +8 more
wiley +1 more source
3D cancer models provide a more reliable representation of drug responses compared to 2D cell culture owing to their 3D architecture and facilitation of cell‐extracellular matrix interactions. In this study, we engineered dense compartmentalized 3D tumoroids composed of breast tumor mass and a surrounding stromal compartment replicating either breast ...
Salma T. Rafik +3 more
wiley +1 more source
Paths to stability - actin regulation of adherens junction mechanics. [PDF]
James J +3 more
europepmc +1 more source
A conformational change in α-catenin's actin-binding domain governs adherens junction maturation. [PDF]
Windgasse L, Grashoff C.
europepmc +1 more source
Signaling from adherens-type junctions
Noam, Erez +2 more
openaire +2 more sources

