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Armadillo is required for adherens junction assembly, cell polarity, and morphogenesis during Drosophila embryogenesis. [PDF]

open access: yesJournal of Cell Biology, 1996
Morphological and biochemical analyses have identified a set of proteins which together form a structure known as the adherens junction. Elegant experiments in tissue culture support the idea that adherens junctions play a key role in cell-cell adhesion ...
Cox, R. T.
exaly   +2 more sources
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Adherens junctions of the human detrusor

BJU International, 2005
OBJECTIVE To immunohistochemically identify the protein composition of adherens junctions, which couple smooth muscle cells mechanically, and to confirm their decrease in different bladder dysfunctions, as studies in geriatric bladder dysfunction show fewer such junctions in patients with detrusor overactivity ...
Nina, Wagener   +8 more
openaire   +2 more sources

The Wnt Signalling Cascade and the Adherens Junction Complex in Craniopharyngioma Tumorigenesis

open access: yesEndocrine Pathology, 2014
Craniopharyngiomas are epithelial, sellar tumours with adamantinomatous (aCP) and papillary (pCP) subtypes. The aCP type usually occurs during childhood and pCP in middle-aged adults; aCPs often contain mutations in CTNNB1, encoding β-catenin, a ...
Veronica Preda   +2 more
exaly   +2 more sources

Adherens Junction Dynamics in the Testis and Spermatogenesis

Journal of Andrology, 2003
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Lee, WM, Lui, WY, Cheng, CY, Mruk, DD
openaire   +4 more sources

Adherens Junctions and Pathogen Entry

2012
Epithelia are highly organised structures protecting underlying tissues against microbial pathogens. Epithelial morphogenesis and maintenance is mediated by cell-cell adhesion molecules organised in junctional complexes, such as the adherens junctions.
Georgios, Nikitas, Pascale, Cossart
openaire   +2 more sources

Adherens Junctions and Cancer

2012
Cadherins and catenins are the central cell-cell adhesion molecules in adherens junctions (AJs). This chapter reviews the knowledge concerning the role of cadherins and catenins in epithelial cancer and examines the published literature demonstrating the changes in the expression and function of these proteins in human cancer and the association of ...
openaire   +2 more sources

Molecular architecture of adherens junctions

Current Opinion in Cell Biology, 2001
Adherens junctions are composed of a cadherin-catenin complex and its associated proteins. Recently, an increasing number of novel members of adherens junctions, including membrane and PDZ proteins, have been reported. Interactions among these components in adherens junctions seem to be dynamically regulated during the formation of adherens junction ...
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Associated proteins of lens adherens junction

Journal of Cellular Biochemistry, 2002
AbstractCytoplasmic proteins associated with adherens junctions were identified in the chicken ocular lens. The catenins, α, β, and γ, were present in epithelial and fiber cells, although their pattern of distribution changed with fiber cell differentiation. The sharp decline in α‐catenin with fiber cell formation and the increasing Triton‐insolubility
M, Bagchi, M, Katar, J, Lewis, H, Maisel
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Adherens junctions in Drosophila retinal morphogenesis

Trends in Cell Biology, 2007
Adherens junctions and their core molecular components, classic cadherins, make major contributions to animal morphogenesis. Although the significance of cadherins in development is generally accepted, the mechanisms regulating adherens junction function during morphogenesis remain a subject of intense research.
Ulrich, Tepass, Kathryn P, Harris
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Formin' adherens junctions

Nature Cell Biology, 2004
Epithelial cells are joined by adherens junctions, which consist of homotypic interactions between extracellular domains of E-cadherins. Inside the cell, the tails of E-cadherins bind actin cables through β-catenin and α-catenin. Formin1 is critically important for the formation of actin cables; it binds directly to α-catenin and can even bypass the ...
openaire   +1 more source

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