Results 41 to 50 of about 344,893 (256)
The Role of Formins in Endothelial Adherens Junction Regulation
, 2016 Adherens junctions are cadherin-dependent structures that mediate intercellular\ud signaling and structural integrity of the endothelial barrier. Formins are a highly\ud conserved family of cytoskeletal remodeling proteins whose activity has been ...
Mumal, Iqra
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Contribution of JAM-1 to epithelial differentiation and tight-junction biogenesis in the mouse preimplantation embryo [PDF]
, 2004 We have investigated the contribution of the tight junction (TJ) transmembrane protein junction-adhesion-molecule 1 (JAM-1) to trophectoderm epithelial differentiation in the mouse embryo.
Fay C. Thomas +11 more
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Signaling from the Adherens Junction [PDF]
, 2012 The cadherin/catenin complex organizes to form a structural Velcro that joins the cytoskeletal networks of adjacent cells. Functional loss of this complex arrests the development of normal tissue organization, and years of research have gone into teasing out how the physical structure of adhesions conveys information to the cell interior. Evidence that
Abbye E, McEwen +2 more
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Endothelial adherens junctions at a glance
Journal of Cell Science, 2013 Adherens junctions have an important role in the control of vascular permeability. These structures are located at cell-to-cell contacts, mediate cell adhesion and transfer intracellular signals. Adhesion is mediated by cadherins, which interact homophilically in trans and form lateral interactions in cis.
E. Dejana, F. Orsenigo
openaire +3 more sources
Adherens Junctions: Guardians of Cortical Development
Frontiers in Cell and Developmental Biology, 2020 Apical radial glia comprise the pseudostratified neuroepithelium lining the embryonic lateral ventricles and give rise to the extensive repertoire of pyramidal neuronal subtypes of the neocortex. The establishment of a highly apicobasally polarized radial glial morphology is a mandatory prerequisite for cortical development as it governs neurogenesis ...
Veeraval, Lenin +2 more
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Interplay between tight junctions & adherens junctions [PDF]
Experimental Cell Research, 2017 Cell-cell adhesions are critical for the development and maintenance of tissues. Present at sites of cell-cell contact are the adherens junctions and tight junctions. The adherens junctions mediate cell-cell adhesion via the actions of nectins and cadherins.
Hannah K, Campbell +2 more
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Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart [PDF]
, 1996 Plakoglobin (gamma-catenin), a member of the armadillo family of proteins, is a constituent of the cytoplasmic plaque of desmosomes as well as of other adhering cell junctions, and is involved in anchorage of cytoskeletal filaments to specific cadherins.
C Birchmeier +23 more
core +1 more source
International Journal of Endocrinology, 2013 In the present study we evaluated in vivo and in vitro effects of 4-tert-octylphenol (OP) on the expression and distribution of adherens and gap junction proteins, N-cadherin, β-catenin, and connexin 43 (Cx43), in testes of seasonally breeding rodents ...
Anna Hejmej +5 more
doaj +1 more source
Junction (Gap, Tight, Adherens) Pathways Mechanistic Genes.
, 2012 Junction (Gap, Tight, Adherens) Pathways Mechanistic Genes.
Sangeeta Khare (141487) +11 more
core +1 more source
Journal of Ophthalmic & Vision Research, 2018 Purpose: Adherens junctions and polarity markers play an important role in maintaining epithelial phenotype but get altered during the epithelial-mesenchymal transition (EMT). Alterations of these markers during EMT of lens epithelial cell (LEC) can lead
Darshini A Ganatra +4 more
doaj +1 more source