Results 21 to 30 of about 32,930 (178)

Molecular anatomy of interendothelial junctions in human blood-brain barrier microvessels.

Folia Histochemica et Cytobiologica, 2004
Immunogold cytochemical procedure was used to study the localization at the ultrastructural level of interendothelial junction-associated protein molecules in the human brain blood microvessels, representing the anatomic site of the blood-brain barrier ...
Andrzej W Vorbrodt, Danuta H Dobrogowska
doaj   +1 more source

Alteration of cell junctions during viral infection

Thoracic Cancer, 2020
Cell junctions serve as a protective barrier for cells and provide an important channel for information transmission between cells and the surrounding environment.
Dan Dong, Wei Xie, Min Liu
doaj   +1 more source

A role for the retinoblastoma protein as a regulator of mouse osteoblast cell adhesion: implications for osteogenesis and osteosarcoma formation.

PLoS ONE, 2010
The retinoblastoma protein (pRb) is a cell cycle regulator inactivated in most human cancers. Loss of pRb function results from mutations in the gene coding for pRb or for any of its upstream regulators.
Bernadette Sosa-García, Volkan Gunduz, Viviana Vázquez-Rivera, W Douglas Cress, Gabriela Wright, Haikuo Bian, Philip W Hinds, Pedro G Santiago-Cardona   +7 more
doaj   +1 more source

Minocycline improves the recovery of nerve function and alleviates blood-brain barrier damage by inhibiting endoplasmic reticulum in traumatic brain injury mice model

European Journal of Inflammation, 2021
Traumatic brain injury (TBI) is a clinical emergency with a very high incidence, disability, and fatality rate. Minocycline, a widely used semisynthetic second-generation tetracycline antibiotic, has anti-inflammatory and bactericidal effects.
Bingbin Wang, Wendong Lin, Haiping Zhu
doaj   +1 more source

Long-term exposure to low concentrations of MC-LR induces blood-testis barrier damage through the RhoA/ROCK pathway

Ecotoxicology and Environmental Safety, 2022
Microcystin-leucine arginine (MC-LR), an emerging water pollutant, produced by cyanobacteria, has an acute testicular toxicity. However, little is known about the chronic toxic effects of MC-LR exposure on the testis at environmental concentrations and ...
Haohao Liu, Xin Zeng, Ya Ma, Xinghai Chen, Michael D. Losiewicz, Xingde Du, Zhihui Tian, Shiyu Zhang, Linjia Shi, Huizhen Zhang, Fei Yang   +10 more
doaj   +1 more source

RETRACTED ARTICLE: Protective role of p120-catenin in maintaining the integrity of adherens and tight junctions in ventilator-induced lung injury

Respiratory Research, 2015
Background Ventilator-induced lung injury (VILI) is one of the most common complications for patients with acute lung injury (ALI) or acute respiratory distress syndrome (ARDS).
Changping Gu, Mengjie Liu, Tao Zhao, Dong Wang, Yuelan Wang   +4 more
doaj   +1 more source

Adherens junction formation inhibits lentivirus entry and gene transfer. [PDF]

PLoS ONE, 2013
Although cellular signaling pathways that affect lentivirus infection have been investigated, the role of cell-cell interactions in lentiviral gene delivery remains elusive.
Roshan Padmashali, Hui You, Nikhila Karnik, Pedro Lei, Stelios T Andreadis   +4 more
doaj   +1 more source

The multifarious regulation of the apical junctional complex [PDF]

Open Biology, 2020
Epithelial cells form highly organized polarized sheets with characteristic cell morphologies and tissue architecture. Cell–cell adhesion and intercellular communication are prerequisites of such cohesive sheets of cells, and cell connectivity is ...
Alexandra D. Rusu, Marios Georgiou
doaj   +1 more source

Photoperiod-Dependent Effects of 4-tert-Octylphenol on Adherens and Gap Junction Proteins in Bank Vole Seminiferous Tubules

International Journal of Endocrinology, 2013
In the present study we evaluated in vivo and in vitro effects of 4-tert-octylphenol (OP) on the expression and distribution of adherens and gap junction proteins, N-cadherin, β-catenin, and connexin 43 (Cx43), in testes of seasonally breeding rodents ...
Anna Hejmej, Malgorzata Kotula-Balak, Katarzyna Chojnacka, Paulina Kuras, Marta Lydka-Zarzycka, Barbara Bilinska   +5 more
doaj   +1 more source

Trichostatin a restores expression of adherens and tight junction proteins during transforming growth factor β-mediated epithelial-to-mesenchymal transition

Journal of Ophthalmic & Vision Research, 2018
Purpose: Adherens junctions and polarity markers play an important role in maintaining epithelial phenotype but get altered during the epithelial-mesenchymal transition (EMT). Alterations of these markers during EMT of lens epithelial cell (LEC) can lead
Darshini A Ganatra, Abhay R Vasavada, Nair G Vidya, Devarshi U Gajjar, Sankaranarayanan Rajkumar   +4 more
doaj   +1 more source