Results 21 to 30 of about 344,893 (256)

Effects of acute and chronic disease on cell junctions in mouse liver

open access: yesEXCLI Journal : Experimental and Clinical Sciences, 2023
Cell junctions, including anchoring, occluding and communicating junctions, play an indispensable role in tissue architecture and homeostasis. Consequently, malfunctioning of cell junctions is linked with a wide range of disorders, including in liver ...
Raf Van Campenhout   +2 more
doaj   +1 more source

p120ctn and P-cadherin but not E-cadherin regulate cell motility and invasion of DU145 prostate cancer cells. [PDF]

open access: yesPLoS ONE, 2010
Adherens junctions consist of transmembrane cadherins, which interact intracellularly with p120ctn, beta-catenin and alpha-catenin. p120ctn is known to regulate cell-cell adhesion by increasing cadherin stability, but the effects of other adherens ...
Sandra Kümper, Anne J Ridley
doaj   +1 more source

Endothelial Adherens Junctions [PDF]

open access: yesJournal of Investigative Dermatology Symposium Proceedings, 2000
The principle of the molecular organization of adherens junctions follows a uniform pattern, which is found in epithelial, muscular, neuroneal as well as in endothelial cells and is highly conserved among species. Transmembrane molecules of the cadherin family link to catenins, which anchor the adhesion plaque to the cytoskeleton.
Petzelbauer, Peter   +2 more
openaire   +2 more sources

Role of spectraplakin in Drosophila photoreceptor morphogenesis. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND:Crumbs (Crb), a cell polarity gene, has been shown to provide a positional cue for the apical membrane domain and adherens junction during Drosophila photoreceptor morphogenesis.
Uyen Ngoc Mui   +2 more
doaj   +1 more source

Scattering of MCF7 cells by heregulin ß-1 depends on the MEK and p38 MAP kinase pathway. [PDF]

open access: yesPLoS ONE, 2013
Heregulin (HRG) β1 signaling promotes scattering of MCF7 cells by inducing breakdown of adherens and tight junctions. Here, we show that stimulation with HRG-β1 causes the F-actin backbone of junctions to destabilize prior to the loss of adherent ...
Rintaro Okoshi   +3 more
doaj   +1 more source

Sorbin and SH3 domain-containing protein 2 (SORBS2) is a component of the acto-myosin ring at the apical junctional complex in epithelial cells. [PDF]

open access: yesPLoS ONE, 2017
SORBS2 is a scaffolding protein associated with Abl/Arg non-receptor tyrosine kinase pathways and is known to interact with actin and several other cytoskeletal proteins in various cell types.
Karin Fredriksson-Lidman   +3 more
doaj   +1 more source

FRAP analysis reveals stabilization of adhesion structures in the epidermis compared to cultured keratinocytes. [PDF]

open access: yesPLoS ONE, 2013
Proper development and tissue maintenance requires cell-cell adhesion structures, which serve diverse and crucial roles in tissue morphogenesis. Epithelial tissues have three main types of cell-cell junctions: tight junctions, which play a major role in ...
Henry P Foote   +2 more
doaj   +1 more source

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