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Regulation of Endothelial Adherens Junctions by Tyrosine Phosphorylation [PDF]
Endothelial cells form a semipermeable, regulated barrier that limits the passage of fluid, small molecules, and leukocytes between the bloodstream and the surrounding tissues.
Alejandro Pablo Adam
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Molecular anatomy of interendothelial junctions in human blood-brain barrier microvessels.
Immunogold cytochemical procedure was used to study the localization at the ultrastructural level of interendothelial junction-associated protein molecules in the human brain blood microvessels, representing the anatomic site of the blood-brain barrier ...
Andrzej W Vorbrodt, Danuta H Dobrogowska
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A New Perspective on Intercalated Disc Organization: Implications for Heart Disease
Adherens junctions and desmosomes are intercellular adhesive junctions and essential for the morphogenesis, differentiation, and maintenance of tissues that are subjected to high mechanical stress, including heart and skin.
Jifen Li, Glenn L. Radice
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Alteration of cell junctions during viral infection
Cell junctions serve as a protective barrier for cells and provide an important channel for information transmission between cells and the surrounding environment.
Dan Dong, Wei Xie, Min Liu
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Traumatic brain injury (TBI) is a clinical emergency with a very high incidence, disability, and fatality rate. Minocycline, a widely used semisynthetic second-generation tetracycline antibiotic, has anti-inflammatory and bactericidal effects.
Bingbin Wang, Wendong Lin, Haiping Zhu
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The retinoblastoma protein (pRb) is a cell cycle regulator inactivated in most human cancers. Loss of pRb function results from mutations in the gene coding for pRb or for any of its upstream regulators.
Bernadette Sosa-García +7 more
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Microcystin-leucine arginine (MC-LR), an emerging water pollutant, produced by cyanobacteria, has an acute testicular toxicity. However, little is known about the chronic toxic effects of MC-LR exposure on the testis at environmental concentrations and ...
Haohao Liu +10 more
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Background Ventilator-induced lung injury (VILI) is one of the most common complications for patients with acute lung injury (ALI) or acute respiratory distress syndrome (ARDS).
Changping Gu +4 more
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Adherens junction formation inhibits lentivirus entry and gene transfer. [PDF]
Although cellular signaling pathways that affect lentivirus infection have been investigated, the role of cell-cell interactions in lentiviral gene delivery remains elusive.
Roshan Padmashali +4 more
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The multifarious regulation of the apical junctional complex [PDF]
Epithelial cells form highly organized polarized sheets with characteristic cell morphologies and tissue architecture. Cell–cell adhesion and intercellular communication are prerequisites of such cohesive sheets of cells, and cell connectivity is ...
Alexandra D. Rusu, Marios Georgiou
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