Results 71 to 80 of about 344,893 (256)
PLoS ONE, 2012 BackgroundThe fibroblast growth factor (FGF) system plays a critical role in the maintenance of vascular integrity via enhancing the stability of VE-cadherin at adherens junctions. However, the precise molecular mechanism is not well understood.
Kunihiko Hatanaka +3 more
doaj +1 more source
Advanced Science, EarlyView.Sepsis‑induced pediatric acute respiratory distress syndrome suppresses FOXF1 in lung endothelial cells which causes life‐threatening lung damage. To counter this, researchers developed nanoparticles that specifically target these cells and deliver FOXF1 mRNA.
Zicheng Deng +14 more
wiley +1 more source
Adherens Junctions and Stem Cells [PDF]
, 2012 The specification, maintenance, division and differentiation of stem cells are integral to the development and homeostasis of many tissues. These stem cells often live in specialized anatomical areas, called niches. While niches can be complex, most involve cell-cell interactions that are mediated by adherens junctions.
openaire +2 more sources
An examination of VEGF, its receptors and the adherens junction component, β-catenin in the development of primary varicose veins [PDF]
, 2010 Vascular endothelial growth factor (VEGF-A) plays a central role in the maintenance of vascular reactivity and its aberrant control/function is implicated in the development of varicose veins (VVs).
Powell, G.L.
core
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Scirrhous gastric cancer, characterized by diffuse infiltration and a high propensity for peritoneal dissemination, remains one of the most aggressive subtypes of gastric cancer. Despite a relatively high incidence of splenic hilar lymph node (No. 10) metastasis, the oncologic benefit of splenectomy remains controversial, while its association
Tsutomu Hayashi, Takaki Yoshikawa
wiley +1 more source
Adherens junction distribution mechanisms during cell-cell contact elongation in Drosophila. [PDF]
PLoS ONE, 2013 During Drosophila gastrulation, amnioserosa (AS) cells flatten and spread as an epithelial sheet. We used AS morphogenesis as a model to investigate how adherens junctions (AJs) distribute along elongating cell-cell contacts in vivo.
Gabrielle Goldenberg, Tony J C Harris
doaj +1 more source
Establishment and characterization of mouse lymph node fibrosis models
Animal Models and Experimental Medicine, EarlyView.The design of the entire paper. Schematic illustration of four strategies for establishing mouse lymph node (LN) fibrosis models. The study further compares their fibrotic remodeling patterns and immune alterations. Abstract Background Lymph node (LN) fibrosis occurs in a variety of pathological conditions, including HIV infection, obesity, cancer, and
Yaru Niu +8 more
wiley +1 more source
eLife, 2017 Detachment of newborn neurons from the neuroepithelium is required for correct neuronal architecture and functional circuitry. This process, also known as delamination, involves adherens-junction disassembly and acto-myosin-mediated abscission, during ...
Ioannis Kasioulis +2 more
doaj +1 more source
Animal Models and Experimental Medicine, EarlyView.The pathogenesis of hypoxic pulmonary hypertension (HPH) remains unclear. In this study, we explored its key regulatory mechanisms using animal models, RNA sequencing, and cellular assays. We found that lncRNA‐92467 functions as a ceRNA, binding miR‐205‐5p, and thereby upregulating PTPRM, inhibiting abnormal proliferation and migration of endothelial ...
Yan‐Ying Shen +7 more
wiley +1 more source
Adherens junction patterns in wild-type and mutant intestines.
, 2016 The images show adherens junctions (white) in the intestines of embryos with the indicated genotypes; the embryos are about 1–2 hours before hatching. The adherens junctions were stained with mAbMH27; the region shown corresponds to the int1-int5 rings ...
Alparsan Asan (2585941) +2 more
core +1 more source