Results 81 to 90 of about 52,251 (235)
Intestinal Barrier Function in Gluten-Related Disorders [PDF]
, 2019 Gluten-related disorders include distinct disease entities, namely celiac disease, wheat-associated allergy and non-celiac gluten/wheat sensitivity. Despite having in common the contact of the gastrointestinal mucosa with components of wheat and other ...
Branchi, Federica +6 more
core +2 more sources
Adherens Junctions and Stem Cells [PDF]
, 2012 The specification, maintenance, division and differentiation of stem cells are integral to the development and homeostasis of many tissues. These stem cells often live in specialized anatomical areas, called niches. While niches can be complex, most involve cell-cell interactions that are mediated by adherens junctions.
openaire +2 more sources
Advanced Science, EarlyView.This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang +7 more
wiley +1 more source
eLife, 2017 Detachment of newborn neurons from the neuroepithelium is required for correct neuronal architecture and functional circuitry. This process, also known as delamination, involves adherens-junction disassembly and acto-myosin-mediated abscission, during ...
Ioannis Kasioulis +2 more
doaj +1 more source
Afadin orients cell division to position the tubule lumen in developing renal tubules [PDF]
, 2017 In many types of tubules, continuity of the lumen is paramount to tubular function, yet how tubules generate lumen continuity in vivo is not known. We recently found the F-actin binding protein Afadin is required for lumen continuity in developing renal ...
Brakeman, Paul R. +9 more
core +2 more sources
The Journal of Cell Biology, 2005 The textbook model of adherens junctions has been exploded, or severed, by Bill Weis, Soichiro Yamada, Frauke Drees, Sabine Pokutta, and W. James Nelson (Stanford University School of Medicine, Stanford, CA). There is no direct link, they say, between cadherin, via β- and α-catenin, to actin.
openaire +2 more sources
Advanced Science, EarlyView.Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha +12 more
wiley +1 more source
Subcellular localisations of the CPTI collection of YFP-tagged proteins in Drosophila embryos. [PDF]
, 2014 A key challenge in the post-genomic area is to identify the function of the genes discovered, with many still uncharacterised in all metazoans. A first step is transcription pattern characterisation, for which we now have near whole-genome coverage in ...
core +1 more source
Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family [PDF]
, 2009 Background: Tight junctions are an intercellular adhesion complex of epithelial and endothelial cells, and form a paracellular barrier that restricts the diffusion of solutes on the basis of size and charge.
Balda, M.S. +3 more
core +3 more sources
Plasmalogen mediates integration of adherens junction
The Journal of Biochemistry, 2019 AbstractEther glycerolipids, plasmalogens are found in various mammalian cells and tissues. However, physiological role of plasmalogens in epithelial cells remains unknown. We herein show that synthesis of ethanolamine-containing plasmalogens, plasmenylethanolamine (PlsEtn), is deficient in MCF7 cells, an epithelial cell line, with severely reduced ...
Takanori Takahashi +3 more
openaire +2 more sources