Results 121 to 130 of about 30,483 (217)

The cytoplasmic domain of adherens‐type junctions [PDF]

Cell Motility, 1991
B, Geiger, D, Ginsberg
openaire   +2 more sources

Coronary Microvascular Dysfunction: Epidemiology, Pathophysiology, Diagnosis, and Treatment

MedComm, Volume 7, Issue 8, August 2026.
This visual summary illustrates the key aspects of coronary microvascular dysfunction (CMD) in angina with nonobstructive coronary artery disease (NOCAD), including epidemiology, pathophysiology (microvascular remodeling and endothelial dysfunction), the protective NRG‐1/ErbB signaling pathway, diagnostic methods, and both Western and traditional ...
Zhao Ge, MaoZe Zhang, Xujin Ning, Yijia Du, Lishuo Su, Xudong Wu, Jingyi Zhang, Tongzuo Liu, Xianliang Wang   +8 more
wiley   +1 more source

AP‐1B Controls Several Levels of Cell Proliferation and Differentiation in Mouse Enteroids

Biology of the Cell, Volume 118, Issue 8, August 2026.
We show that in mouse intestinal organoids, AP‐1B is implicated in apical polarity, differentiation in the secretory lineage and proliferation. In particular, we propose that proliferation is controlled by AP‐1B via the mTOR and YAP pathways. Arrows show the functional links that were elucidated in this study, and dotted lines show putative downstream ...
Maela Duclos, Anne Bourdais, Ophélie Nicolle, Alexandre Helpiquet, Grégoire Michaux, Aurélien Bidaud‐Meynard   +5 more
wiley   +1 more source

Epithelial YPEL3 Modulates CD8+ T‐Cell Infiltration and Tumor Progression Through CREB1–CXCL16 Signaling in HNSCC

Cancer Science, Volume 117, Issue 8, Page 2132-2151, August 2026.
YPEL3 functions as a tumor suppressor in HNSCC by inhibiting tumor progression and promoting apoptosis. Mechanistically, it enhances epithelial–immune crosstalk through the CREB1‐mediated CXCL16–CXCR6 axis, facilitating CD8+ T‐cell infiltration and highlighting its potential as a prognostic biomarker and immunotherapy target.
Yalun Li, Yumei Li, Caiyu Sun, Congxian Lu, Gang Chen, Tianshu Zhou, Bei Zhang, Xicheng Song   +7 more
wiley   +1 more source

Application of Systems Genetics to Investigate Molecular Pathology of Early‐Onset Colorectal Cancer

Chemical Biology &Drug Design, Volume 108, Issue 2, August 2026.
Early‐onset colorectal cancer (EOCRC) presents a complex molecular landscape that requires integrated multi‐omics approaches. This article reviews current applications of systems genetics in EOCRC research and provides a step‐by‐step protocol for network‐based analyses featuring PIK3CA to demonstrate practical application for researchers of all levels.
Minjae J. Kim, Sydney L. Carr, Vishnutheertha Kulkarni, Mary‐Louise Manchadi   +3 more
wiley   +1 more source

Regulation of tension-dependent localization of LATS1 and LATS2 to adherens junctions. [PDF]

PLoS One
De Silva C, Kelch BA, McCollum D.
europepmc   +1 more source

THY1 (CD90) Maintains the Adherens Junctions in Nasopharyngeal Carcinoma via Inhibition of SRC Activation. [PDF]

Cancers (Basel), 2023
Chen L, Chau WY, Yuen HT, Liu XH, Qi RZ, Lung ML, Lung HL.   +6 more
europepmc   +1 more source

Establishment of Human Formative Pluripotent Stem Cell‐Like Cells Exhibiting Amniotic Differentiation Potentials

Cell Proliferation, Volume 59, Issue 8, August 2026.
The hfPSC‐LCs could be established from naïve hESCs, conventional hESCs, hiPSCs, and human blastocysts. The hfPSC‐LCs hold robust capacity for three germ layers, hPGCLCs, and hALPCs. ABSTRACT Human embryos undergo pivotal morphogenetic remodelling shortly after implantation. The understanding of this crucial stage is severely impeded by the scarcity of
Xiaoxiao Wang, Qizhi Wang, Yu Wu, Chen Gu, Mingfei Li, Yong Fan, Xiangjin Kang, Lei Li, Zheng Gao, Mingyan Hei, Jianqiao Liu, Lei Li   +11 more
wiley   +1 more source

VE-cadherin interaction proteomics identifies ARVCF as stabilizer of endothelial adherens junctions. [PDF]

iScience
Schoon RM, van Krimpen-Malinova TS, de Heer I, Hoogendijk AJ, van Alphen FPJ, de Haan A, van Stalborch AD, Tol S, van Buul JD, van den Biggelaar M, Huveneers S.   +10 more
europepmc   +1 more source

Ubiquitin ligase CHFR mediated degradation of VE-cadherin through ubiquitylation disrupts endothelial adherens junctions. [PDF]

Nat Commun, 2023
Tiruppathi C, Wang DM, Ansari MO, Bano S, Tsukasaki Y, Mukhopadhyay A, Joshi JC, Loch C, Niessen HWM, Malik AB.   +9 more
europepmc   +1 more source