Results 131 to 140 of about 34,097 (250)

Adherens junction protein expression is associated with poor response to neoadjuvant FLOT chemotherapy and pro‐inflammatory tumor microenvironment in esophageal adenocarcinoma

International Journal of Cancer, Volume 159, Issue 2, Page 501-515, 15 July 2026.
What's new? Esophageal adenocarcinoma (EAC) is an aggressive cancer with poor survival and variable response to perioperative chemotherapy. Although histopathological features correlate with outcomes, the relationship specifically between adherens junction (AJ) protein expression and treatment response in EAC remains uncertain.
Bastian Grothey, Heike Löser, Tillmann Bedau, Wolfgang Schröder, Christiane J. Bruns, Thomas Zander, Max Krämer, Reinhard Büttner, Alexander Quaas   +8 more
wiley   +1 more source

Intercellular mechanotransduction through adherens junctions in fibroblasts

, 2002
Cells in mechanically active environments form extensive intercellular junctions that are important in tissue remodeling and differentiation. Currently, it is unknown how cells transmit mechanically-induced signals through intercellular junctions.
Ko, Kevin S
core  

Cytoskeletal components of the adherens junctions between the photoreceptors and the supportive müller cells

, 1990
The outer limiting “membrane” (OLM) of the vertebrate retina comprises a series of heterotypic adherens junctions between the photoreceptors and the supportive Müller cells. These junctions appear to support the photoreceptors, which in teleosts, anurans,
PAALLYSAHO, Taru, ARIKAWA, Kentaro, WILLIAMS, David S, 蟻川, 謙太郎   +3 more
core   +1 more source

Actin filament association at adherens junctions

The Journal of Medical Investigation, 2017
The adherens junction (AJ) is a cadherin-based and actin filament associated cell-to-cell junction. AJs can contribute to tissue morphogenesis and homeostasis and their association with actin filaments is crucial for the functions. There are three types of AJs in terms of the mode of actin filament/AJ association.
openaire   +3 more sources

Epigenetic‐Based Evidence for Distinct Effects of Age, Sex, and Experience in Developmental Critical Period Learning

Developmental Neurobiology, Volume 86, Issue 3, July 2026.
ABSTRACT Although much is known about the encoding of experience, how the brain organizes neural circuits capable of learning and memory formation is largely unstudied. Canonical critical periods emerge from a convergence of maturation‐ and experience‐dependent processes.
Grant W. Kunzelman, Alice Batistuzzo, Sarah E. London   +2 more
wiley   +1 more source

LET-413 is a basolateral protein required for the assembly of adherens junctions in Caenorhabditis elegans

, 2000
Epithelial cells are polarized, with apical and basal compartments demarcated by tight and adherens junctions. Proper establishment of these subapical junctions is critical for normal development and histogenesis.
Baillie, David L., David L. Baillie, Gansmuller, Anne, Michel Labouesse, Legouis, Renaud, Anne Gansmuller, Labouesse, Michel, Satis Sookhareea, Renaud Legouis, Sookhareea, Satis, Bosher, Julia M., Julia M. Bosher   +11 more
core   +1 more source

De Novo Genome Assemblies of Four Rainbow Trout Genetic Lines Reveal Structural Variants in Pursuit of a Pangenome Reference

Molecular Ecology Resources, Volume 26, Issue 5, July 2026.
ABSTRACT Rainbow trout (Oncorhynchus mykiss) exhibit extensive genomic diversity shaped by domestication, life history and geographic origin. To advance the development of a comprehensive pangenome reference, we present new de novo genome assemblies of two genetically and ecologically distinct lines: Whale Rock (WR; wild, landlocked, Central California)
Ali Ali, Geoffrey C. Waldbieser, Ramey C. Youngblood, Paul A. Wheeler, Brian E. Scheffler, Stuart Willis, Shawn R. Narum, Gary H. Thorgaard, Mohamed Salem, Yniv Palti   +9 more
wiley   +1 more source

ZO-1 recruitment to  -catenin - a novel mechanism for coupling the assembly of tight junctions to adherens junctions

, 2013
The formation of a barrier between epithelial cells is a fundamental determinant of cellular homeostasis, protecting underlying cells against pathogens, dehydration and damage.
Maiers, Jessica L., Fanning, Alan S., Peng, Xiao, DeMali, Kris A.   +3 more
core   +1 more source

Autoantibodies in Patients With Arrhythmogenic Cardiomyopathy Activate GSK‐3β, Resulting in a Loss of Cardiomyocyte Cohesion

Acta Physiologica, Volume 242, Issue 7, July 2026.
ABSTRACT Background Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiac desmosome disease, as more than 50% of affected patients carry pathogenic variants in desmosome protein‐coding genes. In this study, we focused on the role and mechanisms of pathogenic and non‐pathogenic autoantibodies against intercalated disc (ICD) proteins such as ...
Soumyata Pathak, Konstanze Stangner, Ellen Kempf, Sina Moztarzadeh, Matthias Hiermaier, Stephanie Wider, Marlene Rauschmayer, Tatjana Williams, Andreas Stengl, Brenda Gerull, Ruth Biller, Sebastian Clauss, Stefan Kääb, Tomo Šarić, Sunil Yeruva, Jens Waschke   +15 more
wiley   +1 more source

Fluid Forces Control Structural Remodeling of Blind‐Ended Lymphatic Microvessels

Advanced Healthcare Materials, Volume 15, Issue 21, 5 June 2026.
Using innovative microfluidic biofabrication with fluid mechanical insights, we recapitulated the blind‐ended microanatomy and physiological drainage properties of capillary lymphatics. Our results reveal the interrelationship between intra‐ and extraluminal regions of lymphatic vessels due to flow‐induced sprouting and morphological changes that ...
Jacob C. Holter, Shashwat S. Agarwal, Joseph W. Tinapple, Joseph M. Barlage, Travis H. Jones, Jonathan W. Song   +5 more
wiley   +1 more source