Results 111 to 120 of about 34,097 (250)

Correction to: Disruption of endothelial adherens junctions by high glucose is mediated by protein kinase C-β–dependent vascular endothelial cadherin tyrosine phosphorylation

Cardiovascular Diabetology, 2017
This article was unintentionally published twice in this journal, by the same authors. The following should be considered the version of record and used for citation purposes: “Mehran Haidari, Wei Zhang, James T Willerson and Richard AF Dixon, Disruption
Mehran Haidari, Wei Zhang, James T. Willerson, Richard A. F. Dixon   +3 more
doaj   +1 more source

Beyond the Kidney and Lung: Cutaneous and Mucosal Clues to Human Hantavirus Disease

International Journal of Dermatology, EarlyView.
Rodent exposure and aerosolized excreta can lead to hantavirus infection with systemic endothelial injury and capillary leak, resulting in thrombocytopenia and syndromes such as HPS/HCPS and HFRS/NE. Early dermatologic and mucosal findings, including flushing, conjunctival injection, petechiae/purpura, and mucosal bleeding, may provide important clues ...
Giuseppe Gallo, Pietro Quaglino, Simone Ribero   +2 more
wiley   +1 more source

Darier disease—A review highlighting new insights from the Darier Disease International Task Force

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review provides a global, clinically focused overview of DD, detailing cutaneous and extracutaneous manifestations, disease classification and severity scoring. It emphasizes early recognition, multidisciplinary management and practical guidance for dermatologists to apply evidence‐based care in diverse skin phototypes. Abstract Darier disease (DD)
Sofia Labbouz, Alain Hovnanian, Grace Xiong, Dedee Frances Murrell, Simon M. Mueller, Khaled Ezzedine, Nessa Aghazadeh Mohandesi, Ahmed Salem Aldhaheri, Nissim Asayag, Eulalia Baselga, Chen Nadler, Keith Choate, Chia‐Yu Chu, John Robert Edminister, Emmanuella Guenova, Melis Gönülal, Antoni Gostynski, Ankan Gupta, Lalit Kumar Gupta, Juliette Mazereeuw‐Hautier, Wolfram Hoetzenecker, Peter Itin, Marek Jankowski, Akiharu Kubo, Haur Yueh Lee, Julia Scott Lehman, Anfisa Lepekhova, Márta Medvecz, Jemima E. Mellerio, Verena Moosbrugger‐Martinz, Amy S. Paller, Dóra Plázár, Amadeu José Rodrigues Queiróz, Josep Riera‐Monroig, Ralph Rosa, Matthias Schmuth, Maella Severino Freire, Itzhak Shabat, Jonathan Shapiro, Cory L. Simpson, Diego Soto‐García, Alexander J. Stratigos, Gianluca Abel Tadini, Takuya Takeichi, Kaushal K. Verma, Jakob D. Wikström, Alexander Zink, Michael Ziv, Alexander Navarini, Roni Pircha Dodiuk‐Gad   +49 more
wiley   +1 more source

Adherens junctions and beta-catenin-mediated cell signalling in a non-metazoan organism

, 2000
Mechanical forces between cells have a principal role in the organization of animal tissues. Adherens junctions are an important component of these tissues, connecting cells through their actin cytoskeleton and allowing the assembly of tensile structures.
Shipman, M, Juliet C. Coates, Richard L. Blanton, Adrian J. Harwood, Harwood, A J, Grimson, M J, Reynolds, J P, Jonathan P. Reynolds, Coates, J C, Mark J. Grimson, Blanton, R L, Mark Shipman   +11 more
core   +1 more source

Role of airway epithelial barrier dysfunction in pathogenesis of asthma

Allergology International, 2018
Bronchial asthma is characterized by persistent cough, increased sputum, and repeated wheezing. The pathophysiology underlying these symptoms is the hyper-responsiveness of the airway along with chronic airway inflammation.
Yasuhiro Gon, Shu Hashimoto
doaj   +1 more source

A novel, PCP‐dependent tissue organising principle coordinating morphogenesis between embryonic skin epidermal layers

Journal of Anatomy, EarlyView.
‘Outside‐in’ expression of Fz6 across multiple layers of mouse embryo epidermis is connected to Fz6 asymmetry in the basal layer plane. Fz6 loss‐of‐function correlated with failure to: coordinate axial bias of cell long axis orientation across epidermal layers, switch axial cell long axis orientation during suprabasal layer development and establish ...
C. J. Formstone
wiley   +1 more source

TRIP6 inhibits the Hippo signaling pathway in response to tension at adherens junctions

, 2017
The transcriptional co-activator YAP controls cell proliferation, survival, and tissue regeneration in response to changes in the mechanical environment.
Ishani Dasgupta, Heather Cirka, Kris Billiar, Dannel McCollum, Murugan Paramasivam, Sebastian Mana-Capelli, Shubham Dutta   +6 more
core   +1 more source

Rab7a is required to degrade select blood-brain barrier junctional proteins after ischemic stroke

Acta Neuropathologica Communications
The integrity of adherens and tight junctions is critical for blood-brain barrier (BBB) function in the healthy brain. Disassembly of cell junctions due to degradation of adherens and tight junction-associated proteins leads to acute BBB dysfunction ...
Azzurra Cottarelli, Danny Jamoul, Mary Claire Tuohy, Sanjid Shahriar, Michael Glendinning, Grace Prochilo, Aimee L. Edinger, Ahmet Arac, Dritan Agalliu   +8 more
doaj   +1 more source

Reconstruction of native cellular microanatomy in a novel bioengineered full thickness human nasal mucosal construct

Journal of Anatomy, EarlyView.
Bioengineered tissue constructs are vital technologies employed in in vitro testing of both fundamental biological principles and industrial screening practices. Current approaches to modelling the nasal mucosa in vitro are not representative and are associated with limitations that impact their reliability and predictive value.
Steven Bradbury, Bethany Dickson, Nicola Curtis, David Bunton, Kirsty Goncalves, Stefan Przyborski   +5 more
wiley   +1 more source

The T-type voltage-gated Ca2+ channel CaV3.1 involves in the disruption of respiratory epithelial barrier induced by Pasteurella multocida toxin

Virulence
Pasteurella multocida toxin (PMT) is an exotoxin produced by several members of the zoonotic respiratory pathogen P. multocida. The role of PMT in disrupting the mammalian respiratory barrier remains to be elucidated.
Haixin Bi, Fei Wang, Lin Lin, Dajun Zhang, Menghan Chen, Yuyao Shang, Lin Hua, Huanchun Chen, Bin Wu, Zhong Peng   +9 more
doaj   +1 more source