Results 191 to 200 of about 30,483 (217)
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α-catenin mechanosensing for adherens junctions
Nature Cell Biology, 2010The balance of cohesion and remodelling is essential for the integrity and morphogenesis of epithelia. This requires adhesion and transmission of actomyosin tension, both of which are mediated by E-cadherin. The finding that actomyosin tension reinforces mechanical coupling of actin to E-cadherin through alpha-catenin reveals similarities with integrin
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Cadherin–actin interactions at adherens junctions
Current Opinion in Cell Biology, 2011The adherens junction (AJ) is a major cell-cell junction that mediates cell recognition, adhesion, morphogenesis, and tissue integrity. Although AJs transmit forces generated by actomyosin from one cell to another, AJs have long been considered as an area where signal transduction from cadherin ligation takes place through cell adhesion.
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Adherens junctions as molecular regulators of emergent tissue mechanics
Nature Reviews Molecular Cell Biology, 2023Ivar Noordstra +2 more
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Adherens Junctions During Cell Migration
2012Migration is a key cellular process, involved during morphogenetic movements as well as in the adult where it participates in immune cell trafficking, wound healing or tumour invasion. As they migrate, cells interact with a microenvironment composed of extracellular matrix and neighbouring cells.
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Dynamic contacts: rearranging adherens junctions to drive epithelial remodelling
Nature Reviews Molecular Cell Biology, 2014Masatoshi Takeichi, Takeichi Masatoshi
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Differential positioning of adherens junctions is associated with initiation of epithelial folding
Nature, 2012Eric Wieschaus +2 more
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A non-canonical Notch complex regulates adherens junctions and vascular barrier function
Nature, 2017Karen Hirschi +2 more
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