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Adherens junctions: from molecules to morphogenesis
Nature Reviews Molecular Cell Biology, 2010How adhesive interactions between cells generate and maintain animal tissue structure remains one of the most challenging and long-standing questions in cell and developmental biology. Adherens junctions (AJs) and the cadherin-catenin complexes at their core are therefore the subjects of intense research.
Tony J C Harris +2 more
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Cross-Talk between Adherens Junctions and Desmosomes Depends on Plakoglobin
Journal of Cell Biology, 1997 Squamous epithelial cells have both adherens junctions and desmosomes. The ability of these cells to organize the desmosomal proteins into a functional structure depends upon their ability first to organize an adherens junction.
James K Wahl +2 more
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Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis
Biochimica Et Biophysica Acta - Biomembranes, 2008 International audienceEndothelial cells lining the vessel wall are connected by adherens, tight and gap junctions. These junctional complexes are related to those found at epithelial junctions but with notable changes in terms of specific molecules and ...
Philippe Huber
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Adherens junctions of the human detrusor
BJU International, 2005OBJECTIVE To immunohistochemically identify the protein composition of adherens junctions, which couple smooth muscle cells mechanically, and to confirm their decrease in different bladder dysfunctions, as studies in geriatric bladder dysfunction show fewer such junctions in patients with detrusor overactivity ...
Nina, Wagener +8 more
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Adherens Junction Dynamics in the Testis and Spermatogenesis
Journal of Andrology, 2003link_to_OA_fulltext
Lee, WM, Lui, WY, Cheng, CY, Mruk, DD
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Adherens Junctions and Pathogen Entry
2012Epithelia are highly organised structures protecting underlying tissues against microbial pathogens. Epithelial morphogenesis and maintenance is mediated by cell-cell adhesion molecules organised in junctional complexes, such as the adherens junctions.
Georgios, Nikitas, Pascale, Cossart
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2012
Cadherins and catenins are the central cell-cell adhesion molecules in adherens junctions (AJs). This chapter reviews the knowledge concerning the role of cadherins and catenins in epithelial cancer and examines the published literature demonstrating the changes in the expression and function of these proteins in human cancer and the association of ...
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Cadherins and catenins are the central cell-cell adhesion molecules in adherens junctions (AJs). This chapter reviews the knowledge concerning the role of cadherins and catenins in epithelial cancer and examines the published literature demonstrating the changes in the expression and function of these proteins in human cancer and the association of ...
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Associated proteins of lens adherens junction
Journal of Cellular Biochemistry, 2002AbstractCytoplasmic proteins associated with adherens junctions were identified in the chicken ocular lens. The catenins, α, β, and γ, were present in epithelial and fiber cells, although their pattern of distribution changed with fiber cell differentiation. The sharp decline in α‐catenin with fiber cell formation and the increasing Triton‐insolubility
M, Bagchi, M, Katar, J, Lewis, H, Maisel
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Immunoglobulin Superfamily Receptors and Adherens Junctions
2012The immunogroblin (Ig) superfamily proteins characterized by the presence of Ig-like domains are involved in various cellular functions. The properties of the Ig-like domains to form rod-like structures and to bind specifically to other proteins make them ideal for cell surface receptors and cell adhesion molecules (CAMs).
Yohei, Shimono +4 more
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Trends in Cell Biology, 2002
E-cadherin-based adherens junctions are required for proper adhesion and orientation of epithelial cells within a sheet, as well as playing a role in asymmetric cell division. Although a lot is known – about how E-cadherin-based junctions link to the cytoskeleton, much less is known – about how their localization in the cell is controlled.
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E-cadherin-based adherens junctions are required for proper adhesion and orientation of epithelial cells within a sheet, as well as playing a role in asymmetric cell division. Although a lot is known – about how E-cadherin-based junctions link to the cytoskeleton, much less is known – about how their localization in the cell is controlled.
openaire +1 more source