Results 51 to 60 of about 52,241 (196)
Adherens Junction: Molecular Architecture and Regulation [PDF]
Cold Spring Harbor Perspectives in Biology, 2009 The adherens junction (AJ) is an element of the cell-cell junction in which cadherin receptors bridge the neighboring plasma membranes via their homophilic interactions. Cadherins associate with cytoplasmic proteins, called catenins, which in turn bind to cytoskeletal components, such as actin filaments and microtubules.
Wenxiang, Meng, Masatoshi, Takeichi
openaire +2 more sources
Hydraulic fracturing in cells and tissues: fracking meets cell biology [PDF]
, 2017 The animal body is fundamentally made of water. A small fraction of this water is freely flowing in blood and lymph, but most of it is trapped in hydrogels such as the extracellular matrix (ECM), the cytoskeleton, and chromatin.
Arroyo Balaguer, Marino +1 more
core +4 more sources
Signaling from the Adherens Junction [PDF]
, 2012 The cadherin/catenin complex organizes to form a structural Velcro that joins the cytoskeletal networks of adjacent cells. Functional loss of this complex arrests the development of normal tissue organization, and years of research have gone into teasing out how the physical structure of adhesions conveys information to the cell interior. Evidence that
Abbye E, McEwen +2 more
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Afadin orients cell division to position the tubule lumen in developing renal tubules [PDF]
, 2017 In many types of tubules, continuity of the lumen is paramount to tubular function, yet how tubules generate lumen continuity in vivo is not known. We recently found the F-actin binding protein Afadin is required for lumen continuity in developing renal ...
Brakeman, Paul R. +9 more
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Cell Reports, 2017 Formins are a diverse class of actin regulators that influence filament dynamics and organization. Several formins have been identified at epithelial adherens junctions, but their functional impact remains incompletely understood.
Bipul R. Acharya +7 more
doaj +1 more source
BMC Medicine, 2023 Background Microvascular complications are associated with an overtly increased risk of adverse outcomes in patients with diabetes including coronary microvascular injury which manifested as disruption of adherens junctions between cardiac microvascular ...
Xuebin Zhang +11 more
doaj +1 more source
CDC42 and Rac1 control different actin-dependent processes in the Drosophila wing disc epithelium. [PDF]
, 1995 Cdc42 and Rac1 are members of the rho family of small guanosinetriphosphatases and are required for a diverse set of cytoskeleton-membrane interactions in different cell types.
Auvinen, P +4 more
core
Interactions between Type III receptor tyrosine phosphatases and growth factor receptor tyrosine kinases regulate tracheal tube formation in Drosophila [PDF]
, 2012 The respiratory (tracheal) system of the Drosophila melanogaster larva is an intricate branched network of air-filled tubes. Its developmental logic is similar in some ways to that of the vertebrate vascular system.
Jeon, Mili, Scott, Matthew P., Zinn, Kai
core +3 more sources
Mechanisms of Intestinal Epithelial Barrier Dysfunction by Adherent-Invasive Escherichia coli. [PDF]
, 2016 Pathobiont expansion, such as that of adherent-invasive Escherichia coli (AIEC), is an emerging factor associated with inflammatory bowel disease. The intestinal epithelial barrier is the first line of defense against these pathogens.
McCole, Declan F, Shawki, Ali
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Subcellular localisations of the CPTI collection of YFP-tagged proteins in Drosophila embryos. [PDF]
, 2014 A key challenge in the post-genomic area is to identify the function of the genes discovered, with many still uncharacterised in all metazoans. A first step is transcription pattern characterisation, for which we now have near whole-genome coverage in ...
core +1 more source