Results 31 to 40 of about 30,483 (217)

Interplay between tight junctions & adherens junctions [PDF]

open access: yesExperimental Cell Research, 2017
Cell-cell adhesions are critical for the development and maintenance of tissues. Present at sites of cell-cell contact are the adherens junctions and tight junctions. The adherens junctions mediate cell-cell adhesion via the actions of nectins and cadherins.
Hannah K, Campbell   +2 more
openaire   +2 more sources

Inter-dependent apical microtubule and actin dynamics orchestrate centrosome retention and neuronal delamination

open access: yeseLife, 2017
Detachment of newborn neurons from the neuroepithelium is required for correct neuronal architecture and functional circuitry. This process, also known as delamination, involves adherens-junction disassembly and acto-myosin-mediated abscission, during ...
Ioannis Kasioulis   +2 more
doaj   +1 more source

Sensing Actin Dynamics through Adherens Junctions

open access: yesCell Reports, 2020
Summary: We study punctate adherens junctions (pAJs) to determine how short-lived cadherin clusters and relatively stable actin bundles interact despite differences in dynamics.
Indrajyoti Indra   +4 more
doaj   +1 more source

Loss of Endothelial Barrier Function in the Inflammatory Setting: Indication for a Cytokine-Mediated Post-Transcriptional Mechanism by Virtue of Upregulation of miRNAs miR-29a-3p, miR-29b-3p, and miR-155-5p

open access: yesCells, 2021
Dysfunction of the endothelial barrier plays a central role in the pathogenesis of both acute and chronic inflammatory processes such as sepsis or atherosclerosis.
Daniel Maucher   +2 more
doaj   +1 more source

Endothelial adherens junctions at a glance

open access: yesJournal of Cell Science, 2013
Adherens junctions have an important role in the control of vascular permeability. These structures are located at cell-to-cell contacts, mediate cell adhesion and transfer intracellular signals. Adhesion is mediated by cadherins, which interact homophilically in trans and form lateral interactions in cis.
E. Dejana, F. Orsenigo
openaire   +3 more sources

Signaling from the Adherens Junction [PDF]

open access: yes, 2012
The cadherin/catenin complex organizes to form a structural Velcro that joins the cytoskeletal networks of adjacent cells. Functional loss of this complex arrests the development of normal tissue organization, and years of research have gone into teasing out how the physical structure of adhesions conveys information to the cell interior. Evidence that
Abbye E, McEwen   +2 more
openaire   +2 more sources

Diverse cell junctions with unique molecular composition in tissues of a sponge (Porifera)

open access: yesEvoDevo, 2019
The integrity and organization of animal tissues depend upon specialized protein complexes that mediate adhesion between cells with each other (cadherin-based adherens junctions), and with the extracellular matrix (integrin-based focal adhesions ...
Jennyfer M. Mitchell, Scott A. Nichols
doaj   +1 more source

Molecular components of the adherens junction

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 2008
Adherens junctions serve to couple individual cells into various arrangements required for tissue structure and function. The central structural components of adherens junctions are transmembrane adhesion receptors, and their associated actin-binding/regulatory proteins.
Niessen, Carien M., Gottardi, Cara J.
openaire   +2 more sources

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

open access: yesAdvanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez   +8 more
wiley   +1 more source

Adherens Junction: Molecular Architecture and Regulation [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2009
The adherens junction (AJ) is an element of the cell-cell junction in which cadherin receptors bridge the neighboring plasma membranes via their homophilic interactions. Cadherins associate with cytoplasmic proteins, called catenins, which in turn bind to cytoskeletal components, such as actin filaments and microtubules.
Wenxiang, Meng, Masatoshi, Takeichi
openaire   +2 more sources

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