Results 41 to 50 of about 34,097 (250)

Inter-dependent apical microtubule and actin dynamics orchestrate centrosome retention and neuronal delamination

open access: yeseLife, 2017
Detachment of newborn neurons from the neuroepithelium is required for correct neuronal architecture and functional circuitry. This process, also known as delamination, involves adherens-junction disassembly and acto-myosin-mediated abscission, during ...
Ioannis Kasioulis   +2 more
doaj   +1 more source

Sensing Actin Dynamics through Adherens Junctions

open access: yesCell Reports, 2020
Summary: We study punctate adherens junctions (pAJs) to determine how short-lived cadherin clusters and relatively stable actin bundles interact despite differences in dynamics.
Indrajyoti Indra   +4 more
doaj   +1 more source

Signaling from the Adherens Junction [PDF]

open access: yes, 2012
The cadherin/catenin complex organizes to form a structural Velcro that joins the cytoskeletal networks of adjacent cells. Functional loss of this complex arrests the development of normal tissue organization, and years of research have gone into teasing out how the physical structure of adhesions conveys information to the cell interior. Evidence that
Abbye E, McEwen   +2 more
openaire   +2 more sources

Diverse cell junctions with unique molecular composition in tissues of a sponge (Porifera)

open access: yesEvoDevo, 2019
The integrity and organization of animal tissues depend upon specialized protein complexes that mediate adhesion between cells with each other (cadherin-based adherens junctions), and with the extracellular matrix (integrin-based focal adhesions ...
Jennyfer M. Mitchell, Scott A. Nichols
doaj   +1 more source

Untersuchungen zur Lokalisation und Funktion von Armadillo-Proteinen in Adherens junctions [PDF]

open access: yes, 2020
Adherens junctions sind Zellkontakte, welche den Zellzusammenhalt ermöglichen. Der Aufbau besteht aus transmembranären Proteinen der Cadherin-Familie und intrazellulären Proteinen der p120-Catenine. Die Proteine der p120-Catenine sind multifunktional mit
Frommann, Babett
core   +1 more source

Molecular components of the adherens junction

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 2008
Adherens junctions serve to couple individual cells into various arrangements required for tissue structure and function. The central structural components of adherens junctions are transmembrane adhesion receptors, and their associated actin-binding/regulatory proteins.
Niessen, Carien M., Gottardi, Cara J.
openaire   +2 more sources

Calcium-induced assembly of adherens junctions in keratinocytes. [PDF]

open access: yes, 1987
Extracellular calcium concentration has been shown to control the stratification of cultured keratinocytes, presumably by regulation of formation of desmosomes. Previous studies have shown that keratinocytes cultured in medium containing 0.1 mM Ca++ form
Briggaman, R. A.   +5 more
core   +1 more source

Tissue‐Stimulator Platform for Electrically Stimulating Pancreatic β‐Cells for Long‐Term Functional Regulation

open access: yesAdvanced Functional Materials, EarlyView.
We present a tissue‐stimulator platform for seamless electrode integration with pancreatic tissue, applying uniform electrical stimulation through optimized design with biohybrid 3D printing. Advantageous effects of electrical stimulation on β‐cell function were observed, including enhanced calcium signaling, islet morphology, and maturation.
Jihwan Kim   +7 more
wiley   +1 more source

Mammalian Diaphanous 1 Mediates a Pathway for E-cadherin to Stabilize Epithelial Barriers through Junctional Contractility

open access: yesCell Reports, 2017
Formins are a diverse class of actin regulators that influence filament dynamics and organization. Several formins have been identified at epithelial adherens junctions, but their functional impact remains incompletely understood.
Bipul R. Acharya   +7 more
doaj   +1 more source

Adherens Junction: Molecular Architecture and Regulation [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2009
The adherens junction (AJ) is an element of the cell-cell junction in which cadherin receptors bridge the neighboring plasma membranes via their homophilic interactions. Cadherins associate with cytoplasmic proteins, called catenins, which in turn bind to cytoskeletal components, such as actin filaments and microtubules.
Wenxiang, Meng, Masatoshi, Takeichi
openaire   +2 more sources

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