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Endothelial Adherens Junctions [PDF]
Journal of Investigative Dermatology Symposium Proceedings, 2000 The principle of the molecular organization of adherens junctions follows a uniform pattern, which is found in epithelial, muscular, neuroneal as well as in endothelial cells and is highly conserved among species. Transmembrane molecules of the cadherin family link to catenins, which anchor the adhesion plaque to the cytoskeleton.
Petzelbauer, Peter +2 more
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Endothelial adherens junctions at a glance
Journal of Cell Science, 2013 Adherens junctions have an important role in the control of vascular permeability. These structures are located at cell-to-cell contacts, mediate cell adhesion and transfer intracellular signals. Adhesion is mediated by cadherins, which interact homophilically in trans and form lateral interactions in cis.
E. Dejana, F. Orsenigo
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Adherens Junctions: Demonstration in Human Epidermis [PDF]
Journal of Investigative Dermatology, 1993 Adherens junctions are intercellular and cell-matrix junctions that, like desmosomes and hemidesmosomes, mediate adhesion of cells to each other or to matrix structures. These junctions have been detected recently in cultured human keratinocytes, indicating that they may be of importance in epidermis.
Kaiser, Hans W. +5 more
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Tight Junctions/Adherens Junctions: Basic Structure and Function [PDF]
Journal of Investigative Dermatology, 2007 Adherens and tight junctions are intercellular junctions crucial for epithelial adhesion and barrier function in a wide variety of tissues and organisms. In stratifying epithelia, such as the epidermis, the role of adherens and tight junctions was considered less important owing to the abundance of desmosomes, mediating firm mechanical stability ...
Carien M. Niessen, Niessen, Carien M.
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Adherens junctions modifications in endothelial barrier function.
, 2004 Adherens junctions modifications in endothelial barrier ...
Maria. Konstantoulaki (7972580)
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Nectin stabilization at adherens junctions is counteracted by Rab5a-dependent endocytosis
European Journal of Cell Biology, 2021 Cell-cell junctions undergo constant remodeling, which is crucial for the control of vascular integrity. Indeed, transport of junctional components such as cadherins is understood in increasing depth.
Pasquale Cervero +4 more
doaj +1 more source
Role of spectraplakin in Drosophila photoreceptor morphogenesis. [PDF]
PLoS ONE, 2011 BACKGROUND:Crumbs (Crb), a cell polarity gene, has been shown to provide a positional cue for the apical membrane domain and adherens junction during Drosophila photoreceptor morphogenesis.
Uyen Ngoc Mui +2 more
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Mushroom bodies tiny regulates Sidekick localization to tricellular adherens junctions. [PDF]
DevelopmentThe Drosophila cell-adhesion molecule Sidekick is a key component of tricellular adherens junctions in epithelia and localizes to specific synaptic layers in the optic lobes.
Gandhi D +7 more
europepmc +2 more sources
FRAP analysis reveals stabilization of adhesion structures in the epidermis compared to cultured keratinocytes. [PDF]
PLoS ONE, 2013 Proper development and tissue maintenance requires cell-cell adhesion structures, which serve diverse and crucial roles in tissue morphogenesis. Epithelial tissues have three main types of cell-cell junctions: tight junctions, which play a major role in ...
Henry P Foote +2 more
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p120ctn and P-cadherin but not E-cadherin regulate cell motility and invasion of DU145 prostate cancer cells. [PDF]
PLoS ONE, 2010 Adherens junctions consist of transmembrane cadherins, which interact intracellularly with p120ctn, beta-catenin and alpha-catenin. p120ctn is known to regulate cell-cell adhesion by increasing cadherin stability, but the effects of other adherens ...
Sandra Kümper, Anne J Ridley
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