Results 11 to 20 of about 1,307,359 (192)

Role of hydration in collagen recognition by bacterial adhesins. [PDF]

open access: yesBiophysical Journal, 2011
Protein-protein recognition regulates the vast majority of physiological or pathological processes. We investigated the role of hydration in collagen recognition by bacterial adhesin CNA by means of first principle molecular-dynamics samplings. Our characterization of the hydration properties of the isolated partners highlights dewetting-prone areas on
L. Vitagliano   +2 more
semanticscholar   +5 more sources

Capsule Shields the Function of Short Bacterial Adhesins [PDF]

open access: yesJournal of Bacteriology, 2004
ABSTRACT Bacterial surface structures such as capsules and adhesins are generally regarded as important virulence factors. Here we demonstrate that capsules block the function of the self-recognizing protein antigen 43 through physical shielding.
M. Schembri, D. Dalsgaard, P. Klemm
semanticscholar   +4 more sources

Bacterial adhesins: function and structure.

open access: yesInternational Journal of Medical Microbiology, 2000
Specific adhesion to host tissue cells is an essential virulence factor of most bacterial pathogens. The fundamental processes that determine bacterial attachment to host tissue surfaces are mediated by microbial adhesins. Host specificity and tissue tropism are characteristics exhibited by different bacteria and are determined (at least in part) by ...
P. Klemm, M. Schembri
semanticscholar   +3 more sources

Helicobacter pylori infection: An overview of bacterial virulence factors and pathogenesis

open access: yesBiomedical Journal, 2016
Helicobacter pylori pathogenesis and disease outcomes are mediated by a complex interplay between bacterial virulence factors, host, and environmental factors. After H.
Cheng-Yen Kao   +2 more
doaj   +2 more sources

FaaPred: a SVM-based prediction method for fungal adhesins and adhesin-like proteins. [PDF]

open access: yesPLoS ONE, 2010
Adhesion constitutes one of the initial stages of infection in microbial diseases and is mediated by adhesins. Hence, identification and comprehensive knowledge of adhesins and adhesin-like proteins is essential to understand adhesin mediated ...
Jayashree Ramana, Dinesh Gupta
doaj   +1 more source

Escherichia coli Aggregates Mediated by Native or Synthetic Adhesins Exhibit Both Core and Adhesin-Specific Transcriptional Responses

open access: yesMicrobiology Spectrum, 2023
Bacteria can rapidly tune their physiology and metabolism to adapt to environmental fluctuations. In particular, they can adapt their lifestyle to the close proximity of other bacteria or the presence of different surfaces.
Yankel Chekli   +5 more
doaj   +1 more source

RTX Adhesins are Key Bacterial Surface Megaproteins in the Formation of Biofilms.

open access: yesTrends in Microbiology, 2019
Gram-negative bacteria produce repeats-in-toxin adhesion proteins (RTX adhesins) to facilitate microbial adhesion. These large, multidomain proteins share a common architecture comprised of four regions. First to emerge from the bacterium, C terminal end
Shuaiqi Guo   +4 more
semanticscholar   +2 more sources

Immunoglobulin-fold containing bacterial adhesins: Molecular and structural perspectives in host tissue colonization and infection.

open access: yesFEMS Microbiology Letters, 2020
Immunoglobulin (Ig) domains are one of the most widespread protein domains encoded by the human genome and are present in a large array of proteins with diverse biological functions.
S. Chatterjee   +4 more
semanticscholar   +1 more source

The Mammalian Membrane Microenvironment Regulates the Sequential Attachment of Bacteria to Host Cells

open access: yesmBio, 2021
Pathogen attachment to host tissue is critical in the progress of many infections. Bacteria use adhesion in vivo to stabilize colonization and subsequently regulate the deployment of contact-dependent virulence traits.
Xavier Pierrat   +3 more
doaj   +1 more source

Evolution of host-microbe cell adherence by receptor domain shuffling

open access: yeseLife, 2022
Stable adherence to epithelial surfaces is required for colonization by diverse host-associated microbes. Successful attachment of pathogenic microbes to host cells via adhesin molecules is also the first step in many devastating infections.
EmilyClare P Baker   +6 more
doaj   +1 more source

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