Results 11 to 20 of about 1,156,649 (199)

Bacterial adhesins in host-microbe interactions. [PDF]

open access: yesCell Host & Microbe, 2009
Most commensal and pathogenic bacteria interacting with eukaryotic hosts express adhesive molecules on their surfaces that promote interaction with host cell receptors or with soluble macromolecules. Even though bacterial attachment to epithelial cells may be beneficial for bacterial colonization, adhesion may come at a cost because bacterial ...
K. Kline   +4 more
semanticscholar   +3 more sources

Structural biology of gram‐positive bacterial adhesins [PDF]

open access: yesProtein Science, 2011
AbstractThe structural biology of Gram‐positive cell surface adhesins is an emerging field of research, whereas Gram‐negative pilus assembly and anchoring have been extensively investigated and are well understood. Gram‐positive surface proteins known as MSCRAMMs (microbial surface components recognizing adhesive matrix molecules) and individual ...
K. Vengadesan, S. Narayana
semanticscholar   +3 more sources

Role of hydration in collagen recognition by bacterial adhesins. [PDF]

open access: yesBiophysical Journal, 2011
Protein-protein recognition regulates the vast majority of physiological or pathological processes. We investigated the role of hydration in collagen recognition by bacterial adhesin CNA by means of first principle molecular-dynamics samplings. Our characterization of the hydration properties of the isolated partners highlights dewetting-prone areas on
L. Vitagliano   +2 more
semanticscholar   +5 more sources

FaaPred: a SVM-based prediction method for fungal adhesins and adhesin-like proteins. [PDF]

open access: yesPLoS ONE, 2010
Adhesion constitutes one of the initial stages of infection in microbial diseases and is mediated by adhesins. Hence, identification and comprehensive knowledge of adhesins and adhesin-like proteins is essential to understand adhesin mediated ...
Jayashree Ramana, Dinesh Gupta
doaj   +1 more source

Escherichia coli Aggregates Mediated by Native or Synthetic Adhesins Exhibit Both Core and Adhesin-Specific Transcriptional Responses

open access: yesMicrobiology Spectrum, 2023
Bacteria can rapidly tune their physiology and metabolism to adapt to environmental fluctuations. In particular, they can adapt their lifestyle to the close proximity of other bacteria or the presence of different surfaces.
Yankel Chekli   +5 more
doaj   +1 more source

Immunoglobulin-fold containing bacterial adhesins: Molecular and structural perspectives in host tissue colonization and infection.

open access: yesFEMS Microbiology Letters, 2020
Immunoglobulin (Ig) domains are one of the most widespread protein domains encoded by the human genome and are present in a large array of proteins with diverse biological functions.
S. Chatterjee   +4 more
semanticscholar   +1 more source

The Mammalian Membrane Microenvironment Regulates the Sequential Attachment of Bacteria to Host Cells

open access: yesmBio, 2021
Pathogen attachment to host tissue is critical in the progress of many infections. Bacteria use adhesion in vivo to stabilize colonization and subsequently regulate the deployment of contact-dependent virulence traits.
Xavier Pierrat   +3 more
doaj   +1 more source

Evolution of host-microbe cell adherence by receptor domain shuffling

open access: yeseLife, 2022
Stable adherence to epithelial surfaces is required for colonization by diverse host-associated microbes. Successful attachment of pathogenic microbes to host cells via adhesin molecules is also the first step in many devastating infections.
EmilyClare P Baker   +6 more
doaj   +1 more source

Identification of cell-binding adhesins of Leptospira interrogans. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2014
Leptospirosis is a globally distributed bacterial infectious disease caused by pathogenic members of the genus Leptospira. Infection can lead to illness ranging from mild and non-specific to severe, with jaundice, kidney and liver dysfunction, and ...
Karen V Evangelista   +5 more
doaj   +1 more source

Capsule Shields the Function of Short Bacterial Adhesins [PDF]

open access: yesJournal of Bacteriology, 2004
ABSTRACT Bacterial surface structures such as capsules and adhesins are generally regarded as important virulence factors. Here we demonstrate that capsules block the function of the self-recognizing protein antigen 43 through physical shielding.
M. Schembri, D. Dalsgaard, P. Klemm
semanticscholar   +4 more sources

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