Identification of cell-binding adhesins of Leptospira interrogans. [PDF]
PLoS Neglected Tropical Diseases, 2014 Leptospirosis is a globally distributed bacterial infectious disease caused by pathogenic members of the genus Leptospira. Infection can lead to illness ranging from mild and non-specific to severe, with jaundice, kidney and liver dysfunction, and ...
Karen V Evangelista +5 more
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Yersinia pseudotuberculosis-derived adhesins
Инфекция и иммунитет, 2019 Around fifteen surface components referred to adhesins have been identified in Yersinia pseudotuberculosis combining primarily microbiological, molecular and genetic, as well as immunochemical and biophysical methods. Y.
A. A. Byvalov, I. V. Konyshev
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Identification of novel adhesins of M. tuberculosis H37Rv using integrated approach of multiple computational algorithms and experimental analysis. [PDF]
PLoS ONE, 2013 Pathogenic bacteria interacting with eukaryotic host express adhesins on their surface. These adhesins aid in bacterial attachment to the host cell receptors during colonization.
Sanjiv Kumar +4 more
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Anti-virulence therapeutic strategies against bacterial infections: recent advances.
GERMS, 2022 The emergence and increasing prevalence of multidrug-resistant pathogens has become a major global healthcare problem. According to the World Health Organization if these trends continue, mortality from infection in 2050 will be higher than that from ...
R. Dehbanipour, Z. Ghalavand
semanticscholar +1 more source
Whatever makes them stick - Adhesins of avian pathogenic Escherichia coli.
Veterinary Microbiology, 2021 Avian pathogenic Escherichia coli (APEC) is associated with extraintestinal infections and the development of colibacillosis, causing high mortality in farm birds and extensive losses in the poultry industry worldwide.
Adrianna Aleksandrowicz +4 more
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Adhesins as Targets for Vaccine Development
Emerging Infectious Diseases, 1999 Blocking the primary stages of infection, namely bacterial attachment to host cell receptors and colonization of the mucosal surface, may be the most effective strategy to prevent bacterial infections. Bacterial attachment usually involves an interaction
Theresa M. Wizemann +2 more
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Semiprocessive Hyperglycosylation of Adhesin by Bacterial Protein N -Glycosyltransferases [PDF]
ACS Chemical Biology, 2021 Processivity is an important feature of enzyme families such as DNA polymerases, polysaccharide synthases, and protein kinases, to ensure high fidelity in biopolymer synthesis and modification. Here, we reveal processive character in the family of cytoplasmic protein N-glycosyltransferases (NGTs).
Liubov Yakovlieva +3 more
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Adhesins and host serum factors drive Yop translocation by yersinia into professional phagocytes during animal infection. [PDF]
PLoS Pathogens, 2013 Yersinia delivers Yops into numerous types of cultured cells, but predominantly into professional phagocytes and B cells during animal infection. The basis for this cellular tropism during animal infection is not understood.
Francisco J Maldonado-Arocho +4 more
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mBio, 2021 Bacterial adhesins are key virulence factors that are essential for the pathogen-host interaction and biofilm formation that cause most infections. Many of the adhesin-driven cell-cell interactions are mediated by lectins.
Shuaiqi Guo +7 more
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Beyond Risk: Bacterial Biofilms and Their Regulating Approaches
Frontiers in Microbiology, 2020 Bacterial biofilms are complex surface attached communities of bacteria held together by self-produced polymer matrixs mainly composed of polysaccharides, secreted proteins, and extracellular DNAs. Bacterial biofilm formation is a complex process and can
Musa Hassan Muhammad +8 more
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