Results 21 to 30 of about 1,156,649 (199)

Yersinia pseudotuberculosis-derived adhesins

Инфекция и иммунитет, 2019
Around fifteen surface components referred to adhesins have been identified in Yersinia pseudotuberculosis combining primarily microbiological, molecular and genetic, as well as immunochemical and biophysical methods. Y.
A. A. Byvalov, I. V. Konyshev
doaj   +1 more source

Identification of novel adhesins of M. tuberculosis H37Rv using integrated approach of multiple computational algorithms and experimental analysis. [PDF]

PLoS ONE, 2013
Pathogenic bacteria interacting with eukaryotic host express adhesins on their surface. These adhesins aid in bacterial attachment to the host cell receptors during colonization.
Sanjiv Kumar, Bhanwar Lal Puniya, Shahila Parween, Pradip Nahar, Srinivasan Ramachandran   +4 more
doaj   +1 more source

Anti-virulence therapeutic strategies against bacterial infections: recent advances.

GERMS, 2022
The emergence and increasing prevalence of multidrug-resistant pathogens has become a major global healthcare problem. According to the World Health Organization if these trends continue, mortality from infection in 2050 will be higher than that from ...
R. Dehbanipour, Z. Ghalavand
semanticscholar   +1 more source

Bacterial adhesins: function and structure

International Journal of Medical Microbiology, 2000
Specific adhesion to host tissue cells is an essential virulence factor of most bacterial pathogens. The fundamental processes that determine bacterial attachment to host tissue surfaces are mediated by microbial adhesins. Host specificity and tissue tropism are characteristics exhibited by different bacteria and are determined (at least in part) by ...
Klemm, Per, Schembri, Mark A.
openaire   +2 more sources

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

Periodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra, Hélène Rangé, Giuseppina Caligiuri, Philippe Bouchard   +3 more
wiley   +1 more source

Adhesins as Targets for Vaccine Development

Emerging Infectious Diseases, 1999
Blocking the primary stages of infection, namely bacterial attachment to host cell receptors and colonization of the mucosal surface, may be the most effective strategy to prevent bacterial infections. Bacterial attachment usually involves an interaction
Theresa M. Wizemann, John E. Adamou, Solomon Langermann   +2 more
doaj   +1 more source

Semiprocessive Hyperglycosylation of Adhesin by Bacterial Protein N -Glycosyltransferases [PDF]

ACS Chemical Biology, 2021
Processivity is an important feature of enzyme families such as DNA polymerases, polysaccharide synthases, and protein kinases, to ensure high fidelity in biopolymer synthesis and modification. Here, we reveal processive character in the family of cytoplasmic protein N-glycosyltransferases (NGTs).
Liubov Yakovlieva, Carlos Ramírez-Palacios, Siewert J. Marrink, Marthe T. C. Walvoort   +3 more
openaire   +2 more sources

Adhesins and host serum factors drive Yop translocation by yersinia into professional phagocytes during animal infection. [PDF]

PLoS Pathogens, 2013
Yersinia delivers Yops into numerous types of cultured cells, but predominantly into professional phagocytes and B cells during animal infection. The basis for this cellular tropism during animal infection is not understood.
Francisco J Maldonado-Arocho, Carlos Green, Michael L Fisher, Michelle K Paczosa, Joan Mecsas   +4 more
doaj   +1 more source

Structural Basis of Ligand Selectivity by a Bacterial Adhesin Lectin Involved in Multispecies Biofilm Formation

mBio, 2021
Bacterial adhesins are key virulence factors that are essential for the pathogen-host interaction and biofilm formation that cause most infections. Many of the adhesin-driven cell-cell interactions are mediated by lectins.
Shuaiqi Guo, Tyler D. R. Vance, Hossein Zahiri, Robert Eves, Corey Stevens, Jan-Hendrik Hehemann, Silvia Vidal-Melgosa, Peter L. Davies   +7 more
doaj   +1 more source

pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion

Journal of Experimental Medicine, 2017
Streptococcus pneumoniae is the main cause of bacterial meningitis, a life-threating disease with a high case fatality rate despite treatment with antibiotics.
F. Iovino, Joo-Yeon Engelen-Lee, M. Brouwer, D. van de Beek, A. van der Ende, M. Valls Seron, P. Mellroth, S. Muschiol, Jan Bergstrand, J. Widengren, B. Henriques‐Normark   +10 more
semanticscholar   +1 more source