Results 41 to 50 of about 1,307,359 (192)

CEACAM1 recognition by bacterial pathogens is species-specific

BMC Microbiology, 2010
Background Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), an immunoglobulin (Ig)-related glycoprotein, serves as cellular receptor for a variety of Gram-negative bacterial pathogens associated with the human mucosa.
Kammerer Robert, Bachmann Verena, Voges Maike, Gophna Uri, Hauck Christof R   +4 more
doaj   +1 more source

The Transmembrane Mucin MUC1 Facilitates β1-Integrin-Mediated Bacterial Invasion

mBio, 2021
Bacteria can exploit membrane receptor integrins for cellular invasion, either by direct binding of bacterial adhesins or utilizing extracellular matrix components.
Xinyue Li, Richard W. Wubbolts, Nancy M. C. Bleumink-Pluym, Jos P. M. van Putten, Karin Strijbis   +4 more
doaj   +1 more source

How bacteria hack the matrix and dodge the bullets of immunity

European Respiratory Review, 2018
Haemophilus influenzae, Moraxella catarrhalis and Pseudomonas aeruginosa are common Gram-negative pathogens associated with an array of pulmonary diseases. All three species have multiple adhesins in their outer membrane, i.e.
Magnus Paulsson, Kristian Riesbeck
doaj   +1 more source

An internal thioester in a pathogen surface protein mediates covalent host binding

eLife, 2015
To cause disease and persist in a host, pathogenic and commensal microbes must adhere to tissues. Colonization and infection depend on specific molecular interactions at the host-microbe interface that involve microbial surface proteins, or adhesins.
Miriam Walden, John M Edwards, Aleksandra M Dziewulska, Rene Bergmann, Gerhard Saalbach, Su-Yin Kan, Ona K Miller, Miriam Weckener, Rosemary J Jackson, Sally L Shirran, Catherine H Botting, Gordon J Florence, Manfred Rohde, Mark J Banfield, Ulrich Schwarz-Linek   +14 more
doaj   +1 more source

Structure and Conservation of Amyloid Spines From the Candida albicans Als5 Adhesin

Frontiers in Molecular Biosciences, 2022
Candida Als family adhesins mediate adhesion to biological and abiotic substrates, as well as fungal cell aggregation, fungal-bacterial co-aggregation and biofilm formation.
Nimrod Golan, Sergei Schwartz-Perov, Meytal Landau, Meytal Landau, Peter N. Lipke   +4 more
doaj   +1 more source

Lectin-Glycan Interaction Network-Based Identification of Host Receptors of Microbial Pathogenic Adhesins

mBio, 2016
The first step in the infection of humans by microbial pathogens is their adherence to host tissue cells, which is frequently based on the binding of carbohydrate-binding proteins (lectin-like adhesins) to human cell receptors that expose glycans.
Francesco S. Ielasi, Mitchel Alioscha-Perez, Dagmara Donohue, Sandra Claes, Hichem Sahli, Dominique Schols, Ronnie G. Willaert   +6 more
doaj   +1 more source

Inhibitory effect of natural flavone luteolin on Streptococcus mutans biofilm formation

Microbiology Spectrum, 2023
Streptococcus mutans is one of the key pathogens responsible for dental caries, which is known to be one of the most prevalent biofilm-associated diseases worldwide. S.
Lucille Rudin, Noelle Roth, Julien Kneubühler, Badri Nath Dubey, Michael M. Bornstein, Viktoriya Shyp   +5 more
doaj   +1 more source

Staphylococcus aureus Cell Wall Biosynthesis Modulates Bone Invasion and Osteomyelitis Pathogenesis

Frontiers in Microbiology, 2021
Staphylococcus aureus invasion of the osteocyte lacuno-canalicular network (OLCN) is a novel mechanism of bacterial persistence and immune evasion in chronic osteomyelitis. Previous work highlighted S.
Elysia A. Masters, Elysia A. Masters, Gowrishankar Muthukrishnan, Gowrishankar Muthukrishnan, Lananh Ho, Lananh Ho, Ann Lindley Gill, Karen L. de Mesy Bentley, Karen L. de Mesy Bentley, Karen L. de Mesy Bentley, Chad A. Galloway, Chad A. Galloway, James L. McGrath, Hani A. Awad, Hani A. Awad, Steven R. Gill, Edward M. Schwarz, Edward M. Schwarz, Edward M. Schwarz, Edward M. Schwarz   +19 more
doaj   +1 more source

Sensing and adhesion are adaptive functions in the plant pathogenic xanthomonads

BMC Evolutionary Biology, 2011
Background Bacterial plant pathogens belonging to the Xanthomonas genus are tightly adapted to their host plants and are not known to colonise other environments. The host range of each strain is usually restricted to a few host plant species.
Manceau Charles, Barbe Valérie, Fouteau Stéphanie, Durand Karine, Pigné Sandrine, Darrasse Armelle, Mhedbi-Hajri Nadia, Lemaire Christophe, Jacques Marie-Agnès   +8 more
doaj   +1 more source

In-Silico Analysis Highlights the Existence in Members of Burkholderia cepacia Complex of a New Class of Adhesins Possessing Collagen-like Domains

Microorganisms, 2023
Burkholderia cenocepacia is a multi-drug-resistant lung pathogen. This species synthesizes various virulence factors, among which cell-surface components (adhesins) are critical for establishing the contact with host cells.
Ricardo Estevens, Dalila Mil-Homens, Arsenio M. Fialho   +2 more
doaj   +1 more source