Results 1 to 10 of about 1,819,567 (281)
Nature CommunicationsTalin regulates crucial cellular functions, including cell adhesion and motility, and affects human diseases. Triggered by mechanical forces, talin plays crucial roles in facilitating the formation of focal adhesions and recruiting essential focal ...
Erumbi S. Rangarajan +3 more
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Junctional Adhesion Molecules (JAMs): The JAM-Integrin Connection
Cells, 2018 Junctional adhesion molecules (JAMs) are cell surface adhesion receptors of the immunoglobulin superfamily. JAMs are involved in a variety of biological processes both in the adult organism but also during development.
Daniel Kummer, Klaus Ebnet
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Macromolecular Materials and EngineeringAs environmental problems increase, disposable products are being replaced and recommended with materials with a low environmental load when it discarded. So the demand for bioplastics for building a sustainable society is increasing.
Ji‐Hyun Cho +2 more
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Scientific Reports, 2017 Mutations in the X-linked gene Protocadherin-19 (Pcdh19) cause female-limited epilepsy and mental retardation in humans. Although Pcdh19 is known to be a homophilic cell-cell adhesion molecule, how its mutations bring about female-specific disorders ...
Shuichi Hayashi +6 more
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Taiwanese Journal of Obstetrics and GynecologyIntrauterine adhesions (IUA) occurred in the reproductive-age women are a big economic and health problem, resulting in severe impairment of social, psychological and physical function of the female genital organs. IUA-related symptoms or signs are varied greatly from free of symptoms or ambiguous symptoms (an incidental finding during the intervention)
Peng-Hui Wang +5 more
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Thrombomodulin: A Bifunctional Modulator of Inflammation and Coagulation in Sepsis
Critical Care Research and Practice, 2012 Deregulated interplay between inflammation and coagulation plays a pivotal role in the pathogenesis of sepsis. Therapeutic approaches that simultaneously target both inflammation and coagulation hold great promise for the treatment of sepsis ...
Takayuki Okamoto +3 more
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The Rac3 GTPase in Neuronal Development, Neurodevelopmental Disorders, and Cancer
Cells, 2019 Rho family small guanosine triphosphatases (GTPases) are important regulators of the cytoskeleton, and are critical in many aspects of cellular and developmental biology, as well as in pathological processes such as intellectual disability and cancer. Of
Ivan de Curtis
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Dual specificity kinase DYRK3 regulates cell migration by influencing the stability of protrusions
iScienceSummary: Plasma membrane-associated platforms (PMAPs) form at specific sites of plasma membrane by scaffolds including ERC1 and Liprin-α1. We identify a mechanism regulating PMAPs assembly, with consequences on motility/invasion. Silencing Ser/Thr kinase
Martina Ramella +8 more
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Applied Sciences, 2018 As a result of industrialization and environmental pollution, increasing importance is being given to eco-friendly materials and technology. In particular, eco-friendly biocomposites using polylactic acid (PLA) have attracted great interest. In this work,
Taek-Jun Chung +6 more
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