Results 1 to 10 of about 929,251 (155)

An investigation of gecko attachment on wet and rough substrates leads to the application of surface roughness power spectral density analysis

Scientific Reports, 2022
The roughness and wettability of surfaces exploited by free-ranging geckos can be highly variable and attachment to these substrates is context dependent (e.g., presence or absence of surface water). Although previous studies focus on the effect of these
Amanda M. Palecek, Austin M. Garner, Mena R. Klittich, Alyssa Y. Stark, Jacob D. Scherger, Craig Bernard, Peter H. Niewiarowski, Ali Dhinojwala   +7 more
doaj   +1 more source

Distinct inter-domain interactions of dimeric versus monomeric α-catenin link cell junctions to filaments

Communications Biology, 2023
CryoEM structures capture the initial α-catenin interaction with F-actin before the sensing of force.
Erumbi S. Rangarajan, Emmanuel W. Smith, Tina Izard   +2 more
doaj   +1 more source

Probing mechanical interaction of immune receptors and cytoskeleton by membrane nanotube extraction

Scientific Reports, 2023
The role of force application in immune cell recognition is now well established, the force being transmitted between the actin cytoskeleton to the anchoring ligands through receptors such as integrins. In this chain, the mechanics of the cytoskeleton to
Fabio Manca, Gautier Eich, Omar N’Dao, Lucie Normand, Kheya Sengupta, Laurent Limozin, Pierre-Henri Puech   +6 more
doaj   +1 more source

Controlling T cells spreading, mechanics and activation by micropatterning

Scientific Reports, 2021
We designed a strategy, based on a careful examination of the activation capabilities of proteins and antibodies used as substrates for adhering T cells, coupled to protein microstamping to control at the same time the position, shape, spreading ...
Anaïs Sadoun, Martine Biarnes-Pelicot, Laura Ghesquiere-Dierickx, Ambroise Wu, Olivier Théodoly, Laurent Limozin, Yannick Hamon, Pierre-Henri Puech   +7 more
doaj   +1 more source

miRNA-200c-3p targets talin-1 to regulate integrin-mediated cell adhesion

Scientific Reports, 2021
The ability of integrins on the cell surface to mediate cell adhesion to the extracellular matrix ligands is regulated by intracellular signaling cascades.
Gideon Obeng, Eun Jeong Park, Michael G. Appiah, Eiji Kawamoto, Arong Gaowa, Motomu Shimaoka   +5 more
doaj   +1 more source

EpCAM promotes endosomal modulation of the cortical RhoA zone for epithelial organization

Nature Communications, 2021
The organization and force-generating property of actomyosin dictate the plasticity and behaviour of cells but the spatio-temporal regulation of this network is unclear.
Cécile Gaston, Simon De Beco, Bryant Doss, Meng Pan, Estelle Gauquelin, Joseph D’Alessandro, Chwee Teck Lim, Benoit Ladoux, Delphine Delacour   +8 more
doaj   +1 more source

Potential Roles of Muscle-Derived Extracellular Vesicles in Remodeling Cellular Microenvironment: Proposed Implications of the Exercise-Induced Myokine, Irisin

Frontiers in Cell and Developmental Biology, 2021
Extracellular vesicles (EVs) have emerged as key players of intercellular communication and mediate crosstalk between tissues. Metastatic tumors release tumorigenic EVs, capable of pre-conditioning distal sites for organotropic metastasis.
Samuel Darkwah, Eun Jeong Park, Phyoe Kyawe Myint, Atsushi Ito, Atsushi Ito, Michael G. Appiah, Gideon Obeng, Eiji Kawamoto, Eiji Kawamoto, Motomu Shimaoka   +9 more
doaj   +1 more source

The Spike Glycoprotein of SARS-CoV-2 Binds to β1 Integrins Expressed on the Surface of Lung Epithelial Cells

Viruses, 2021
The spike glycoprotein attached to the envelope of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to and exploits angiotensin-converting enzyme 2 (ACE2) as an entry receptor to infect pulmonary epithelial cells.
Eun Jeong Park, Phyoe Kyawe Myint, Michael Gyasi Appiah, Samuel Darkwah, Siqingaowa Caidengbate, Atsushi Ito, Eri Matsuo, Eiji Kawamoto, Arong Gaowa, Motomu Shimaoka   +9 more
doaj   +1 more source

Adhesion and Adhesives [PDF]

SHINKU, 1966
Adhesion and Adhesives Edited by Dr. R. Houwink and Dr. G. Salomon. Vol. 1: Adhesives. Second, completely revised edition. Pp. xvi + 548. (Amsterdam, London and New York: Elsevier Publishing Company, 1965.) 135s.
openaire   +4 more sources

Targeted remodeling of breast cancer and immune cell homing niches by exosomal integrins

Diagnostic Pathology, 2020
Exosomes represent an important subset of extracellular vesicles involved in inter-cellular communications in health and diseases. Exosomes secreted from cancer and immune cells travel to the specific tissues containing homing niches.
Phyoe Kyawe Myint, Eun Jeong Park, Arong Gaowa, Eiji Kawamoto, Motomu Shimaoka   +4 more
doaj   +1 more source