Results 121 to 130 of about 1,357,755 (309)

Recombinant Human Soluble Thrombomodulin Suppresses Monocyte Adhesion by Reducing Lipopolysaccharide-Induced Endothelial Cellular Stiffening

open access: yes, 2020
Endothelial cellular stiffening has been observed not only in inflamed cultured endothelial cells but also in the endothelium of atherosclerotic regions, which is an underlying cause of monocyte adhesion and accumulation.
OKAMOTO, Takayuki   +17 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

INVESTIGATION OF THE EFFECTS OF THE SURFACE QUALITY ON THE MECHANICAL PROPERTIES OF ADHESION

open access: yes, 2022
The reason I have choosen the topic ,,Investigation of the effects of the surface quality on the mechanical properties of adhesion” is because there are more and more different kind of adhesive technologies and in opinion it is important to give them ...
Karakuş, Göksu
core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Carbamylated low-density lipoprotein and adhesion molecules

open access: yes, 2016
Carbamylated LDL (cLDL), the most abundant modifi ed LDL isoform in human blood, has been recently implicated in causing atherosclerosis-prone injuries to endothelial cells in vitro and atherosclerosis in patients with chronic kidney disease.
Basnakian A.G.   +3 more
core  

Mechanics of Adhesion in MEMS-a Review

open access: yes, 2003
A review is presented of the mechanics of microscale adhesion in microelectromechanical systems (MEMS). Some governing dimensionless numbers such as Tabor number, adhesion parameter and peel number for microscale elastic adhesion contact are discussed in
赵亚溥, 余同希, 王立森
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Adhesion molecules in dementia

open access: yes, 2016
During the past decade it has become evident that immunological, infl ammatory and vascular processes play an important role in the etiology and pathogenesis of various neuro-degenerative diseases.
Jianping, Jia,   +3 more
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

The Effects of Roughness on Adhesion Hysteresis

open access: yes, 2010
Adhesion hysteresis is defined as the difference between the work needed to separate two surfaces and that originally gained on bringing them together. Adhesion hysteresis is a common phenomenon in most surface/interface interactions.
魏征, He MF, Zhao YP, 赵亚溥
core   +1 more source

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