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Dual implication of endothelial adhesion molecules in tumor progression and cancer immunity [PDF]
Cell Adhesion & MigrationAdhesion molecules are proteins expressed at the surface of various cell types. Their main contribution to immunity is to allow the infiltration of immune cells in an inflamed site.
Louis-Emmanuel Chriqui +2 more
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Citrus flavonoids and adhesion molecules: Potential role in the management of atherosclerosis [PDF]
Heliyon, 2023 Atherosclerosis as a chronic inflammatory disorder is accompanied with oxidative stress which causes a high morbidity and mortality. Adhesion molecules, including intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), P ...
Farnaz Ebrahimi +3 more
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Circulating cell adhesion molecules in systemic sclerosis: a systematic review and meta-analysis [PDF]
Frontiers in ImmunologyIntroductionPatients with systemic sclerosis (SSc) have an increased risk of endothelial dysfunction, atherosclerosis, and cardiovascular events compared to the general population.
Arduino A. Mangoni +2 more
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Circulating LPS from gut microbiota leverages stenosis-induced deep vein thrombosis in mice
Thrombosis Journal, 2023 Objective and design An accumulating body of evidence has shown that gut microbiota is involved in regulating inflammation; however, it remains undetermined if and how gut microbiota plays an important role in modulating deep venous thrombosis (DVT ...
Cheng Liu +9 more
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Adhesion molecules: a way to understand lupus
Rheumatology, 2022 Systemic lupus erythematosus is a connective disease in which all vitally important organs may be affected. The etiology of the disease is largely unknown and almost all immunological mechanisms have been proposed as the pathophysiological background of ...
Karolina Nowak +2 more
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Cell Adhesion Molecules in Fibrotic Diseases
Biomedicines, 2023 Mechanisms underlying the pathogenesis of tissue fibrosis remain incompletely understood. Emerging evidence suggests that cell adhesion molecules (CAMs) are critical in fibrotic progression in many organs, including lung, kidney, skin, and liver.
Qianjiang Hu +5 more
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Sharpin suppresses β1-integrin activation by complexing with the β1 tail and kindlin-1
Cell Communication and Signaling, 2019 Background Previously sharpin has been identified as an endogenous inhibitor of β1-integrin activation by directly binding to a conserved region in the cytoplasmic tails (CTs) of the integrin β1-associated α subunits. Methods Here we employed biochemical
Juan Gao +12 more
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Circulating adhesion molecules and arterial stiffness [PDF]
, 2015 Aim: VCAM-1 and ICAM-1 are two important members of the immunoglobulin gene superfamily of adhesion molecules, and their potential role as biomarkers of diagnosis, severity and prognosis of cardiovascular disease has been investigated in a number of ...
Alihanoglu, Y.I. +6 more
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Animal lectins as cell adhesion molecules [PDF]
, 1998 Protein-carbohydrate interaction is exploited in cell adhesion mechanisms besides the recognition of peptide motifs. The sugar code thus significantly contributes to the intriguing specificity of cellular selection of binding partners.
Kaltner, H., Stierstorfer, B.
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VCAM-1 and ICAM-1 serum levels as markers of relapse in visceral leishmaniasis
Mediterranean Journal of Hematology and Infectious Diseases, 2017 Objectives-Methods. Visceral leishmaniasis (VL) is characterized by chronicity and relapses despite efficacious treatment. Acute and chronic inflammatory processes and concomitant disturbances in cell adhesion characterize the pathogenesis of the disease.
Alexandros Makis +5 more
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