Results 51 to 60 of about 839,688 (290)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

THE STUDY OF SOLUBLE ADHESION MOL¬ECULES (SICAM-1, SVCAM-1, SELAM-1) IN SE¬RUM AND MEMBRANE FORM OF ADHESION MOLECULES (VCAM-1, ICAM-1) ON THE MONO¬CYTES IN DIABETIC SUBJECTS TYPE 1

Iranian Journal of Allergy, Asthma and Immunology, 2000
The adhesion molecules are involved in adhesion of leukocytes to endothelial cells and other immune cells. Not only adhesion molecules have membrane form, but they also have soluble form.
K. Bahman Sufiani, Sh. Shar Gasimpour, A.R. Salek Mogaddam,   K. Entezami, A. Rajab   +4 more
doaj  

Immunohistochemical study of adhesion molecules in irritable bowel syndrome: A comparison to inflammatory bowel diseases

Advanced Biomedical Research, 2021
Background: The surface of endothelial cells is covered with cell adhesion molecules including E-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule 1 (VCAM-1) that mediate the adhesion and extravasation of ...
Antigony Mitselou, Vasileios Grammeniatis, Anna Varouktsi, Stamatis S Papadatos, Antonios Klaroudas, Konstantinos Katsanos, Vasiliki Galani   +6 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Neural cell adhesion molecules

The Turkish Journal of Pediatrics, 1991
Adhesion molecules are expressed on the surface of various cells and establish cell-cell interaction, playing important roles in development, inflammatory reaction, immune response, and tissue regeneration.
B Anlar
doaj  

Cadherin Cell Adhesion System in Canine Mammary Cancer: A Review

Veterinary Medicine International, 2012
Cadherin-catenin adhesion complexes play important roles by providing cell-cell adhesion and communication in different organ systems. Abnormal expression of cadherin adhesion molecules constitutes a common phenomenon in canine mammary cancer and has ...
Adelina Gama, Fernando Schmitt
doaj   +1 more source

Junctional Adhesion Molecules (JAMs): The JAM-Integrin Connection

Cells, 2018
Junctional adhesion molecules (JAMs) are cell surface adhesion receptors of the immunoglobulin superfamily. JAMs are involved in a variety of biological processes both in the adult organism but also during development.
Daniel Kummer, Klaus Ebnet
doaj   +1 more source

Perinatal Inflammation: Could Partial Blocking of Cell Adhesion Molecule Function Be a Solution?

Children, 2021
In spite of the great advances made in recent years in prenatal and perinatal medicine, inflammation can still frequently result in injury to vital organs and often constitutes a major cause of morbidity.
Nikolaos Vrachnis, Dimitrios Zygouris, Dionysios Vrachnis, Nikolaos Roussos, Nikolaos Loukas, Nikolaos Antonakopoulos, Georgios Paltoglou, Stavroula Barbounaki, Georgios Valsamakis, Zoi Iliodromiti   +9 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Ligand-Receptor Interactions

, 2008
The formation and dissociation of specific noncovalent interactions between a variety of macromolecules play a crucial role in the function of biological systems.
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core   +1 more source