Results 91 to 100 of about 733,023 (334)

The use of clamping grips and friction pads by tree frogs for climbing curved surfaces [PDF]

open access: yes, 2017
Most studies on the adhesive mechanisms of climbing animals have addressed attachment against flat surfaces, yet many animals can climb highly curved surfaces, like twigs and small branches.
Barnes, W. Jon P.   +7 more
core   +2 more sources

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Lysozyme, anti-lysozyme, hemolytic and adhesive activity in serration cultures isolated from dairy products [PDF]

open access: yesBIO Web of Conferences
Federal state budgetary educational institution of higher education “Chechen state University. Isolation of pathogenic or opportunistic bacteria from surrounding environment, food products, animals and humans requires establishing their potential ...
Gairabekov R.Kh.   +2 more
doaj   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Some fundamentals of adhesion in synthetic adhesives [PDF]

open access: yesBiofouling, 2003
Various adhesion mechanisms that have been understood in the field of synthetic adhesives are described and these are linked with situations relevant to fouling issues. The review mainly deals with mechanical aspects of adhesion phenomena, with an emphasis on the role of the elasticity of the bodies, called substrata, attached by adhesive.
openaire   +4 more sources

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

An embedding theorem for adhesive categories

open access: yes, 2011
Adhesive categories are categories which have pushouts with one leg a monomorphism, all pullbacks, and certain exactness conditions relating these pushouts and pullbacks. We give a new proof of the fact that every topos is adhesive.
Lack, Stephen
core   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

Nondestructive testing of adhesive bonds by nuclear quadrupole resonance method [PDF]

open access: yes, 1971
Inert, strain sensitive tracer, cuprous oxide, added to polymeric adhesive ensures sufficiently large signal to noise ratio in NQR system output. Method is successful, provided that RF-transparent structural materials are used between modified adhesive ...
Hewitt, R. R.
core   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

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